CorEvitas Inflammatory Bowel Disease (IBD) Drug Safety and Effectiveness Registry

Date Added
June 8th, 2022
PRO Number
Pro00120887
Researcher
Erin Forster

List of Studies


Keywords
Crohn's Disease, Digestive System, Non-interventional
Summary

This is a prospective, observational research study for patients with IBD under the care of a gastroenterologist provider. The objective of the Corrona Inflammatory Bowel Diseases (IBD) Registry is to create a national cohort of patients with IBD.The diseases under study include Crohn's Disease (CD), Ulcerative Colitis (UC) and Indeterminate Colitis (IC). Data collected will be used to better characterize the natural history of the disease and to extensively evaluate the effectiveness and safety of medications approved for the treatment of IBD .Approximately 10,000 patients and 150 clinical sites in North America will be recruited to participate with no defined upper limit for either target. The Corrona IBD Registry is a long-term observational study; therefore, the duration of the registry has no pre-determined stop date.

Institution
MUSC
Recruitment Contact
Zerlinna Teague
(843) 792-1221
recruitment@musc.edu

EPH Septic Shock Observational Study (ESSOS)

Date Added
May 16th, 2022
PRO Number
Pro00119078
Researcher
Andrew Goodwin

List of Studies


Keywords
Genetics, Immune System, Inflammation, Non-interventional
Summary

This is a multicenter, prospective cohort study. This is an observational study with no intervention. The study will consist of data collection via patient/surrogate interview and medical record review and collection of blood during the first three days of septic shock treatment . Blood samples will undergo RNA sequencing, which will be used to classify patients into sepsis phenotypes. Written informed consent from the patient or legally authorized representative (LAR) will be obtained.

Data will be collected for up to 90 days after enrollment. For patients discharged from the hospital prior to Day 28, three post-discharge assessment will be made at Day 28, Day 60, and Day 90 to ascertain vital status.

Institution
MUSC
Recruitment Contact
Zerlinna Teague
(843) 792-0965
shannonz@musc.edu

Feasibility of a Cannabis Study in Peripartum Women

Date Added
April 19th, 2022
PRO Number
Pro00119473
Researcher
Constance Guille

List of Studies


Keywords
Mental Health, Non-interventional, Pregnancy, Psychiatry, Substance Use, Women's Health
Summary

The purpose of the study is to 1) determine the most practical study recruitment strategies for pregnant and postpartum women with marijuana use and 2) collect data to determine what types of studies pregnant and postpartum women are willing to take part in. Participation involves completing an online survey that takes about 10 minutes to complete.

Institution
MUSC
Recruitment Contact
Edie Douglas
843-792-5958
douglaed@musc.edu

Alpha-1 Antitrypsin Disease Cohort: Longitudinal Biomarker Study of Disease Consortium

Date Added
March 16th, 2022
PRO Number
Pro00117423
Researcher
Charlie Strange

List of Studies


Keywords
Autoimmune disease, Liver, Lung, Non-interventional, Pulmonary, Rare Diseases
Summary

The purpose of this study is to create a de-identified, public use,
repository of data of Chronic Obstructive Pulmonary Disease (COPD)
patients with by Alpha-1 antitrypsin deficiency (AATD), a rare genetic
condition that can cause COPD and emphysema.

Institution
MUSC
Recruitment Contact
Kristin Neff
843-792-1219
neffk@musc.edu

DeepView SnapShot Portable (DV-SSP): Device Training Study

Date Added
March 7th, 2022
PRO Number
Pro00116561
Researcher
Steven Kahn

List of Studies


Keywords
Non-interventional, Surgery
Summary

This study will optimize the DeepView SnapShot Portable device by imaging patients' burn wounds. These images contribute to the machine learning technology that will one day be used to aid burn clinicians in their treatment plans. Patients will be approached by the burn study team at the hospital when they initially come in for a burn wound treatment. Duration of the study for patients is 21 days.

Institution
MUSC
Recruitment Contact
Jason Hirsch
843-792-8824
hirschj@musc.edu

Assessment of cortical network connectivity in individuals with impaired walking coordination post-stroke

Date Added
July 6th, 2021
PRO Number
Pro00111026
Researcher
Steven Kautz

List of Studies


Keywords
Muscle, Non-interventional, Rehabilitation Studies, Stroke Recovery
Summary

Transcranial magnetic stimulation (TMS) is a non-invasive brain stimulation method often used to assess connectivity between the brain and specific muscles. This research study is aimed at finding the changes in the manner brain communicates with leg muscles post-stroke and its effects on movement coordination during walking.

Institution
MUSC
Recruitment Contact
Shraddha Srivastava
8437926165
srivasts@musc.edu

Olfactory Dysfunction in Aging Adults

Date Added
June 25th, 2021
PRO Number
Pro00111776
Researcher
Rodney Schlosser

List of Studies


Keywords
Aging, Non-interventional, Nose
Summary

Smell loss has been reported in more than 50% of older adults. Currently there are no validated methods for classifying patients with smell loss in aging based on either disease site or process. This study aims to better understand how age affects the sense of smell. This study will involve those 50 and older and will take up to 2 years, with 2 follow up annual visits.

Institution
MUSC
Recruitment Contact
Tina LaPointe
843-792-9496
storck@musc.edu