Disentangling Reward/Anti-reward Circuits in Opioid Users with Chronic Low Back Pain

Date Added
May 18th, 2021
PRO Number
Pro00106192
Researcher
Catherine Hubbard

List of Studies


Keywords
Brain, Drug Studies, Pain
Summary

This project uses advanced analytical approaches in functional magnetic resonance imaging, at the level of the individual, to expand our current understanding of the brain changes responsible for driving an individual's susceptibility or resistance toward prescription opioid misuse in patients with chronic low back pain.

Institution
MUSC
Recruitment Contact
Catherine Hubbard
843-792-9502
precisionimaginglab@musc.edu

Internet-delivered Management of Pain Among Cancer Treatment Survivors (IMPACTS)

Date Added
April 12th, 2021
PRO Number
Pro00109105
Researcher
Sarah Price

List of Studies


Keywords
Cancer, Pain
Summary

The study is being done to find out if this approach (8 sessions of the Internet-based program with education) is better or worse than the usual approach plus education only for cancer-related pain. The usual approach is defined as care most people get for cancer-related pain.

Institution
MUSC
Recruitment Contact
HCC Clinical Trials Office
(843) 792-9321
hcc-clinical-trials@musc.edu

Sex Differences in the Effects of Early Childhood Adversity on Laboratory-Induced Stress and Craving among Individuals with Opioid Use Disorder

Date Added
February 2nd, 2021
PRO Number
Pro00104087
Researcher
Delisa Brown

List of Studies


Keywords
Drug Studies, Pain, Psychiatry, Stress Disorders, Substance Use
Summary

This study will examine the effects of early childhood adversity on stress and craving among individuals with opioid use disorder. Study participants will complete a total of three visits, including a 1-month follow-up visit. Participants will be asked to complete questionnaires about thier mood, anxiety, drug use, craving and adverse childhood events. They will listen to personalized scripts about a stressful situation, a time when they used opioid and a relaxing situation and their heart rate, skin conductance and cortisol are measured.

Institution
MUSC
Recruitment Contact
Delisa Brown
843-792-2388
browdg@musc.edu

The effect of multi-modal minocycline and N-acetylcysteine for the treatment of fibromyalgia: a double-blind, randomized, crossover pilot study.

Date Added
January 19th, 2021
PRO Number
Pro00102425
Researcher
Michael Hillegass

List of Studies


Keywords
Fibromyalgia, Pain
Summary

The purpose of the research is to evaluate the effectiveness of using two common drugs together to reduce chronic pain specifically in patients with fibromyalgia. These two drugs are minocycline and N-acetylcysteine . Minocycline is an antibiotic, and N-acetylcysteine is a supplement that can reduce cell damage. Minocycline and N-acetylcysteine are not FDA approved for chronic pain but have been proven in animal studies to interact with important cells in the body that play a major role in the development of chronic pain.

Institution
MUSC
Recruitment Contact
Wanda Jones
843-792-1869
joneswr@musc.edu

Predictive Chronic Wound Monitor for Healing Assessment via Intelligent Sensor Fusion

Date Added
August 4th, 2020
PRO Number
Pro00100687
Researcher
Teresa Kelechi

List of Studies