RECOVERS – Realigning Emotion and COgnition Via prEcision Regulation networkS – Phase I Study: Multimodal Computational Modeling of Cognitive Flexibility and Emotion Regulation Networks

Date Added
July 5th, 2023
PRO Number
Pro00129566
Researcher
Lisa McTeague

List of Studies


Keywords
Healthy Volunteer Studies
Summary

In this research study, we are using examining how brain activity (electrical and blood flow) changes during tests of emotional processing and attention and memory in the magnetic resonance imaging (MRI) scanner. We are also using non-invasive brain stimulation to probe different parts of the brain and measuring brain activity (electrical and blood flow). This study includes healthy participants and researchers hope this will help us develop improved brain-based treatments for emotional difficulties like depression.

Institution
MUSC
Recruitment Contact
Sarah Huffman
8437925560
huffmans@musc.edu

Evaluating the effects of transcranial focused ultrasound (tFUS) on fronto-striatal resting state functional connectivity in healthy individuals

Date Added
April 4th, 2023
PRO Number
Pro00127562
Researcher
Bashar Badran

List of Studies


Keywords
Healthy Volunteer Studies
Summary

This study is a brain imaging and brain stimulation study that will test a new form of brain stimulation which uses sound. We plan to evaluate whether transcranial focused ultrasound (tFUS), will impact the way the brain communicates 10 healthy individuals. If successful, we will better understand how sound may change brain function.

Institution
MUSC
Recruitment Contact
Emeline Spake
843-792-9502
spake@musc.edu

MPFC Theta Burst Stimulation as a Tool to Affect Rational Decision Making

Date Added
March 7th, 2023
PRO Number
Pro00126644
Researcher
Lisa McTeague

List of Studies


Keywords
Brain, Healthy Volunteer Studies
Summary

This is a study to investigate if a device that temporarily changes brain activity (repetitive transcranial magnetic stimulation, rTMS) might be used to change how healthy participants make decisions. This study involves 2 visits to MUSC that will each take between 2-3 hours. This study is not a treatment study, but it could help inform studies investigating treatment in the future. Participants in this study will be compensated for their time.

Institution
MUSC
Recruitment Contact
Samantha LaPorta
8432592680
laporta@musc.edu

Probing mechanisms of procedural memory transformation with cross-frequency transcranial alternating current stimulation (cf-tACS) as an avenue to sculpt sensorimotor behavior

Date Added
March 7th, 2023
PRO Number
Pro00126392
Researcher
Kirstin-Friederike Heise

List of Studies

Keywords
Aging, Central Nervous System, Healthy Volunteer Studies, Memory Loss
Summary

Sometimes, it is necessary to re-learn a previously learned movement behavior, for example, a bad posture during the golf drive or while playing the piano. Unlearning or relearning an intensively trained behavior is particularly important if the behavior is hampering recovery, for example, in chronic pain or after a stroke. With this study, we experimentally test the brain mechanisms that control the change of pre-existing stable memories of a motor skill with electroencephalography (EEG). We will then use non-invasive brain stimulation to modulate these brain mechanisms and test if it is possible to change the pre-existing motor memory and the learning of a new motor skill.

Institution
MUSC
Recruitment Contact
Valerie Salisbury
843-792-6150
iNRLab@musc.onmicrosoft.com

PRagmatic EValuation of evENTs And Benefits of Lipid-lowering in oldEr adults (PREVENTABLE)

Date Added
March 6th, 2023
PRO Number
Pro00125689
Researcher
Leslie Lenert

List of Studies