Clinical Feasibility of Low Intensity Focused Ultrasound Pulsation for the Treatment of Treatment Resistant Major Depressive Disorder

Date Added
September 5th, 2023
PRO Number
Pro00128763
Researcher
Charles Palmer

List of Studies

Keywords
Depression, Mental Health, Psychiatry
Summary

The purpose of this pilot study is to evaluate safety and efficacy of a novel treatment, low intensity focused ultrasound pulsation (LIFUP) for treatment resistant depression (TRD). The initial visit will involve consent and an MRI scan, followed by two more visits treatment visits over the course of one week. During the first treatment day, participants will receive either focused ultrasound or sham stimulation. On the second treatment day, all participants will receive focused ultrasound. Response and potential side effects will be monitored pre- and post- each treatment along with one week and one month follow-up assessments.

Institution
MUSC
Recruitment Contact
Charles Palmer
843-697-9989
palmecha@musc.edu

An Electrophysiological Predictor of SSRI Response in Veterans with PTSD

Date Added
April 4th, 2023
PRO Number
Pro00124873
Researcher
Zhewu Wang

List of Studies


Keywords
Mental Health, Military, Psychiatry
Summary

By doing this study, we hope to learn if a brief screening method can predict which people are most likely to show a positive response to selective serotonin reuptake inhibitor (SSRI) medications. This brief screening method involves using electrodes attached to your scalp via a cap, to measure electrical brain activity in response to a series of loud tones.
Your participation in this research will last about 17-21 weeks if you decide to stay for the whole study.

Institution
MUSC
Recruitment Contact
Erica Cortes
843-829-2110 xt 1011
erica.cortes@va.gov