A Prospective, Randomized, Comparative Effectiveness Study Comparing Direct Selective Laser Trabeculoplasty (DSLT) and Selective Laser Trabeculoplasty (SLT) in Reducing Intraocular Pressure in Open-Angle Glaucoma

Date Added
April 21st, 2026
PRO Number
Pro00150296
Researcher
Jella An

List of Studies

Keywords
Disease Prevention
Summary

This study compares two common laser treatments used to lower eye pressure in participants with glaucoma or high eye pressure. Both procedures, Selective Laser Trabeculoplasty (SLT) and Direct Selective Laser Trabeculoplasty (DSLT), are established standard-of-care medical treatments. Participants are randomly assigned by a computer to receive one of these two lasers to compare efficacy and safety. To maintain clinical consistency, both eyes of each participant receive the same assigned laser treatment during a single visit. There are no additional research-only appointments required beyond standard clinical care. The study team reviews medical records from the participants' standard 3, 6, and 12-month clinical follow-up visits. This research aims to help clinicians understand which treatment is more effective or efficient for future use. Participation is entirely voluntary and does not impact the quality of medical care provided at the institution.

Institution
MUSC
Recruitment Contact
Muhammad Abrar Irfan
8439260040
irfan@musc.edu

Longitudinal assessment of age-related swallowing changes and potential biological correlates

Date Added
April 7th, 2026
PRO Number
Pro00149182
Researcher
Janina Wilmskoetter

List of Studies


Keywords
Aging, Disease Prevention, Healthy Volunteer Studies
Summary

This study will examine the factors that contribute to changes in swallowing as people age. Over the next ten years, researchers will follow healthy adults (age 18 and older) to see if swallowing becomes more difficult with age. They will also look at whether changes in the brain, thinking skills, and body chemistry are connected to swallowing problems. The information from this study may help doctors find ways to address problems such as choking or aspiration pneumonia in older adults.

Participants can change their mind and stop participating at any time, for any reason. Leaving the study will not affect any benefits or care they are entitled to.

If you would like to learn more, please contact the study team.

Institution
MUSC
Recruitment Contact
Janina Wilmskoetter
843-548-1053
wilmskoe@musc.edu

Pilot Test of an Innovative Implementation Strategy to Improve Reach, Quality, and Equity in Child Maltreatment Prevention

Date Added
November 14th, 2024
PRO Number
Pro00141218
Researcher
Hannah Espeleta

List of Studies

Keywords
Disease Prevention, Healthy Volunteer Studies, Infant
Summary

Millions of children are victims of maltreatment each year in the United States. Research on home visiting programs show that child maltreatment can be prevented; however, these programs struggle to reach families in need and provide high quality care. SafeCare is a sustainable and effective home visiting child maltreatment prevention program, serving over 8,000 families each year. This study will examine the feasibility and implementation of a hybrid in-person/virtual delivery model for SafeCare with 12 home visiting providers and 40 caregivers to inform how home visiting programs are delivered to maximize reach to families, improve family outcomes, and decrease harm to children.

Institution
MUSC
Recruitment Contact
Gabriela Becerra
(843) 792-4202
becerra@musc.edu

Novel Magnetic Resonance Imaging Techniques For Quantitative Cardiac Parametric Mapping

Date Added
June 20th, 2014
PRO Number
Pro00035552
Researcher
Akos Varga-Szemes

List of Studies


Keywords
Cardiovascular, Disease Prevention, Heart
Summary

Heart disease can be detected in the hospital by Cardiac Magnetic Resonance (CMR)- a device that uses a large magnet. CMR is used to test how healthy the heart muscle is and how well the heart is pumping. We will test a new method to see how helpful it is to quickly get good pictures and if this is useful for testing the health of heart muscle in patients with heart disease.

Institution
MUSC
Recruitment Contact
Brett Harris
843 876 8497
harrisbs@musc.edu



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