Identification of a Proinflammatory Biomarker Differentiating Meniere's disease and Vestibular Migraine

Date Added
April 7th, 2020
PRO Number
Pro00097605
Researcher
Habib Rizk

List of Studies

Keywords
Ears, Hearing, Inflammation
Summary

Meniere's disease is a common cause of vertigo that becomes more common with age. Unfortunately, Meniere's disease and vestibular migraine have significant overlap and are sometimes difficult to diagnose. This is due to a lack of understanding of the true cause of Meniere's disease. Due to the lack of a biomarker (an objective test), the diagnosis of Meniere's disease has been based on clinical history and hearing loss. We are exploring ways to differentiate Meniere's disease and vestibular migraine, potentially through a lab test. In addition, identifying biomarkers may help early diagnosis and direct more personalized treatment strategies, especially early on before hearing loss occurs.

Institution
MUSC
Recruitment Contact
Habib Rizk
843 876-0112
rizkh@musc.edu

Comparison of Quality of Life and Functional Outcomes in Adult Cochlear Implant Recipients

Date Added
May 23rd, 2019
PRO Number
Pro00085904
Researcher
Theodore McRackan

List of Studies

Keywords
Hearing
Summary

The purpose of this study is to evaluate participants Quality of Life (QOL) with their Cochlear implant (CI) through a variety of questionnaires and hearing tests.

There will be a pre-surgical visit as well as 3, 6, and 12 month post-surgery visits. In this study, the participants will take surveys and hearing tests at each visit. He or she will complete surveys on the computer through REDCap and the hearing tests will be completed in sound-attenuating booth using headphones in the Walton Research building on MUSC's campus. The study participation is complete once the participant has completed all 4 study visits.

Institution
MUSC
Recruitment Contact
Cameron Thomas
843-876-7069
thomasca@musc.edu

Neural Determinants of Age-Related Change in Auditory-Visual Speech Processing

Date Added
September 24th, 2017
PRO Number
Pro00070971
Researcher
James Dias

List of Studies

Keywords
Aging, Brain, Central Nervous System, Ears, Healthy Volunteer Studies, Hearing, Language, Minorities, Vision/ Eye
Summary

Older adults typically have trouble identifying the speech they hear, especially in noisy environments. Fortunately, compared to younger adults, older adults are better able to compensate for difficulties identifying the speech they hear by recruiting the visual system. However, the extent to which older adults can benefit from visual input, and how this influence relates to age-related changes in brain structure and function, have not been thoroughly investigated. The general purpose of this study is to determine how age-related changes in brain structure and function affect how well people hear and see. This study seeks participants with normal hearing to mild hearing loss, who also have normal or corrected-to-normal vision.

Institution
MUSC
Recruitment Contact
James Dias
(843) 792-3921
diasj@musc.edu

Cochlear Implantation Quality of Life Measure Final Validation

Date Added
September 19th, 2017
PRO Number
Pro00070645
Researcher
Theodore McRackan

List of Studies

Keywords
Hearing, Surgery
Summary

In the first arm of this study (Pro00063109) we developed a list of questions that will be utilized in a new quality of life questionnaire for cochlear implant users. We developed a survey to be used in the clinical setting based on these questions. We would like to gather data from a large number of implant users in order to validate the questionnaire. In the survey subjects are asked how hearing loss and having a cochlear implant affects their life. Enrolled subjects will complete the combined experimental survey paired with the current gold standard quality of life measures at two time points two weeks apart, greater than a year after receiving cochlear implantation.

Institution
MUSC
Recruitment Contact
Joshua Fabie
7178017021
fabie@musc.edu

Understanding cognitive and neurobiological factors of age-related speech recognition declines

Date Added
May 31st, 2017
PRO Number
Pro00064829
Researcher
Kenneth Vaden

List of Studies

Keywords
Aging, Brain, Central Nervous System, Healthy Volunteer Studies, Hearing
Summary

As people get older, understanding speech with competing talkers can become more difficult. The MUSC Hearing Research Program is seeking healthy adults aged 50 to 89 years to participate in a research study investigating the connection between hearing and the brain. Payment is provided for participation, and scheduling is flexible. The study involves two to four visits. Participants must be able to complete an MRI. Please contact us if you would like to participate in this research or learn more about our study.

Institution
MUSC
Recruitment Contact
Brittany Glaze
843-792-5916
glaze@musc.edu



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