Establishing face and content validity of the Cochlear Implant Quality of Life staging system

Date Added
May 16th, 2021
PRO Number
Pro00107776
Researcher
Theodore McRackan

List of Studies


Keywords
Hearing
Summary

This is a qualitative research study focused on refining the presentation of outcome scores from the CIQOL-35 instrument by performing key informant interviews. CIQOL-35 patient profiles will be used to develop a preliminary staging system to classify patient outcomes. Interview questions will be developed based on the language and phrasing of the staging system. Clinician and patient participants will be scheduled or recruited to participate in 10 to 25-minute interviews. Participants will consist of pre-implantation patients, post implantation patients, and clinicians that work with CI patients (doctors, audiologists, counselors and rehabilitation staff). Each group will consist of up to 50 subjects answering questions about how well the language and terminology of the CIQOL-35 items and staging system reflect their experiences. Results will be used to develop and refine the language used to describe CI-patient abilities and the CIQOL-35 staging system for describing clinical outcomes.

Institution
MUSC
Recruitment Contact
David Aamodt
843-876-7069
aamodt@musc.edu

Longitudinal Assessment of Cochlear Implant Outcomes in Adults

Date Added
December 4th, 2020
PRO Number
Pro00104076
Researcher
Theodore McRackan

List of Studies


Keywords
Hearing
Summary

Patient-reported outcome measures (PROMs) are crucial for understanding the impact of cochlear implants (CIs) on real-world functional abilities and quality of life (QOL) and for monitoring changes over time. However, CI clinical outcome measures traditionally focus solely on CI users' speech recognition ability to evaluate treatment success, which limits our understanding of CI's effects on patients' social isolation, emotional impact, and mental and listening effort related to severe hearing loss. Moreover, patient's speech recognition scores demonstrate low correlations with CI users' real-world communication experiences and QOL. Therefore, there is a critical gap in the measures commonly used to quantify patient outcomes after CI activation. To address this gap, we developed the Cochlear Implant Quality of Life (CIQOL)-35 Profile instrument, which provides a comprehensive, patient-centered assessment of CI-related functional abilities and QOL. However, difficultly in interpreting an individual patient's PROM score is a major barrier for PROM implementation and applications to clinical care. Therefore, additional work is critical for clinicians to appropriately interpret CIQOL-35 Profile scores for individual patients and apply those results to inform intervention decisions and monitor patient progress. In the current study we will longitudinally assess CI users CIQOL scores to help identify CI users with lower functional abilities who may benefit from increased support and allow clinicians to better track functional improvement after implantation for individual patients. This work will inform patient discussions regarding expected outcomes and timeframe for improvement.

Institution
MUSC
Recruitment Contact
Cheng Ma
1-843-876-7069
mache@musc.edu

Identification of a Proinflammatory Biomarker Differentiating Meniere's disease and Vestibular Migraine

Date Added
April 7th, 2020
PRO Number
Pro00097605
Researcher
Habib Rizk

List of Studies


Keywords
Ears, Hearing, Inflammation
Summary

Meniere's disease is a common cause of vertigo that becomes more common with age. Unfortunately, Meniere's disease and vestibular migraine have significant overlap and are sometimes difficult to diagnose. This is due to a lack of understanding of the true cause of Meniere's disease. Due to the lack of a biomarker (an objective test), the diagnosis of Meniere's disease has been based on clinical history and hearing loss. We are exploring ways to differentiate Meniere's disease and vestibular migraine, potentially through a lab test. In addition, identifying biomarkers may help early diagnosis and direct more personalized treatment strategies, especially early on before hearing loss occurs.

Institution
MUSC
Recruitment Contact
Habib Rizk
843 876-0112
rizkh@musc.edu

Comparison of Quality of Life and Functional Outcomes in Adult Cochlear Implant Recipients

Date Added
May 23rd, 2019
PRO Number
Pro00085904
Researcher
Theodore McRackan

List of Studies


Keywords
Hearing
Summary

The purpose of this study is to evaluate participants Quality of Life (QOL) with their Cochlear implant (CI) through a variety of questionnaires and hearing tests.

There will be a pre-surgical visit as well as 3, 6, and 12 month post-surgery visits. In this study, the participants will take surveys and hearing tests at each visit. He or she will complete surveys on the computer through REDCap and the hearing tests will be completed in sound-attenuating booth using headphones in the Walton Research building on MUSC's campus. The study participation is complete once the participant has completed all 4 study visits.

Institution
MUSC
Recruitment Contact
Cameron Thomas
843-876-7069
thomasca@musc.edu

Neural Determinants of Age-Related Change in Auditory-Visual Speech Processing

Date Added
September 24th, 2017
PRO Number
Pro00070971
Researcher
James Dias

List of Studies


Keywords
Aging, Brain, Central Nervous System, Ears, Healthy Volunteer Studies, Hearing, Language, Minorities, Vision/ Eye
Summary

Older adults typically have trouble identifying the speech they hear, especially in noisy environments. Fortunately, compared to younger adults, older adults are better able to compensate for difficulties identifying the speech they hear by recruiting the visual system. However, the extent to which older adults can benefit from visual input, and how this influence relates to age-related changes in brain structure and function, have not been thoroughly investigated. The general purpose of this study is to determine how age-related changes in brain structure and function affect how well people hear and see. This study seeks participants with normal hearing to mild hearing loss, who also have normal or corrected-to-normal vision.

Institution
MUSC
Recruitment Contact
James Dias
(843) 792-3921
diasj@musc.edu

Cochlear Implantation Quality of Life Measure Final Validation

Date Added
September 19th, 2017
PRO Number
Pro00070645
Researcher
Theodore McRackan

List of Studies


Keywords
Hearing, Surgery
Summary

In the first arm of this study (Pro00063109) we developed a list of questions that will be utilized in a new quality of life questionnaire for cochlear implant users. We developed a survey to be used in the clinical setting based on these questions. We would like to gather data from a large number of implant users in order to validate the questionnaire. In the survey subjects are asked how hearing loss and having a cochlear implant affects their life. Enrolled subjects will complete the combined experimental survey paired with the current gold standard quality of life measures at two time points two weeks apart, greater than a year after receiving cochlear implantation.

Institution
MUSC
Recruitment Contact
Joshua Fabie
7178017021
fabie@musc.edu

Understanding cognitive and neurobiological factors of age-related speech recognition declines

Date Added
May 31st, 2017
PRO Number
Pro00064829
Researcher
Kenneth Vaden

List of Studies


Keywords
Aging, Brain, Central Nervous System, Healthy Volunteer Studies, Hearing
Summary

As people get older, understanding speech with competing talkers can become more difficult. The MUSC Hearing Research Program is seeking healthy adults aged 50 to 89 years to participate in a research study investigating the connection between hearing and the brain. Payment is provided for participation, and scheduling is flexible. The study involves two to four visits. Participants must be able to complete an MRI. Please contact us if you would like to participate in this research or learn more about our study.

Institution
MUSC
Recruitment Contact
Brittany Glaze
843-792-5916
glaze@musc.edu



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