Mom Era, Reclaimed: Measuring Change in Stress, Wellbeing and Occupational Balance Among Student Moms

Date Added
September 3rd, 2026
PRO Number
Pro00152874
Researcher
Zesarae Bodie

List of Studies

Keywords
Women's Health
Summary

As a part of their 2nd year curriculum, OT students offer a virtual wellness program, for graduate students, aged 18+, who are parenting, and it is called Mom Era, Reclaimed. It is led by the students and facilitated by faculty. The program runs for 6 weeks and is designed to help student moms manage stress, feel more connected to themselves and others, and build daily routines that work better for their lives as both students and parents. This study seeks to learn whether this kind of program is helpful for student moms, so it can be improved and possibly offered to more students in the future.
Participating students will be surveyed at the beginning of the first session and then again at the end of the final session to measure change in their perceptions of their stress, wellbeing and occupational balance. Student moms do not have to participate in the survey to be a part of the the wellness group, the survey is optional and will not affect their participation in the larger group.

Institution
MUSC
Recruitment Contact
Zesarae Bodie
(843) 548-1036
bodiez@musc.edu

An Open Label Extension, Multi-Center Study to Evaluate the Safety of SD-101 Cream in Subjects with Epidermolysis Bullosa

Date Added
September 3rd, 2026
PRO Number
Pro00152287
Researcher
Lara Wine Lee

List of Studies


Keywords
Skin
Summary

Epidermolysis Bullosa is a genetic disorder manifesting typically at birth comprising several genetic subtypes that manifest as blistering or erosion of the skin in response to little or no apparent trauma. This clinical study is being conducted for research purposes. The cream being studied has allantoin as the active ingredient and the aim of this study is to assess the long-term safety of this cream when applied to the skin of participants with Epidermolysis Bullosa. This study is an open label extension to study SD-007. The study will be conducted by the study doctor, in other words, the physician responsible for the clinical study at your child's study site. Your child's participation in the clinical study is expected to last for approximately 12 months and approximately eighty (80) children will participate in this study. There will be a total of five (5) study visits over the course of one year. Study visits 1, 3 and 5 will be in person and visits 2 and 4 will be telephone visits.

Institution
MUSC
Recruitment Contact
Kennedy McLeod
843-792-4091
mcleodke@musc.edu

An Exploratory Study of the Potential for Rational Immune System Manipulation to Prevent Emergence of Synucleinopathy Manifestations in Persons with REM Sleep Behavior Disorder (RBD)

Date Added
September 3rd, 2026
PRO Number
Pro00151041
Researcher
Christine Cooper

List of Studies


Keywords
Parkinsons, Sleep Disorders
Summary

The purpose of this study is to determine if a drug called adalimumab can reduce or prevent emergence or progression of synuclein-related neurodegeneration, or nerve cell death, in people diagnosed with REM Sleep Behavior Disorder (RBD.) About 108 individuals, aged 50-80, will be enrolled in this study, half of whom will receive the active study drug and half of whom will receive placebo. Participants would receive 40 mg adalimumab, administered subcutaneously every 2 weeks or matching placebo for up to 2 years (96 weeks).

Institution
MUSC
Recruitment Contact
Sandra Wilson
8437924616
movementresearch@musc.edu

MOLGRAMOSTIM NEBULIZER SOLUTION EXPANDED ACCESS PROGRAM (EAP)

Date Added
September 3rd, 2026
PRO Number
Pro00150750
Researcher
Aravind Menon

List of Studies

Keywords
Pulmonary
Summary

Treating autoimmune pulmonary alveolar proteinosis (aPAP) patients with molgramostim nebulizer solution focuses on improving how the lungs function and defend against infection. In this condition, the lungs struggle to clear a natural substance called surfactant, which can make breathing harder. A protein in the body called granulocyte macophage colony-stimulating factor (GM‑CSF) helps activate immune cells that keep the lungs clean and healthy. These cells play an important role in removing buildup and protecting against germs. Increasing their activity can help the lungs work more efficiently. It also helps reduce lung damage by boosting the number of these helpful cells. In addition, this protein supports the formation of certain blood cells that are important for overall health. Molgramostim is a man-made version of this natural protein. It is delivered directly into the lungs using a nebulizer, allowing it to work where it is needed most. Research studies have shown that this treatment is generally safe, well tolerated, and can improve symptoms in people with autoimmune PAP.

Institution
MUSC
Recruitment Contact
Zerlinna Teague
(843) 792-0965
recruitment@musc.edu

Dynamic patterns of oral nicotine pouch use and transitions in cigarette and smokeless tobacco use: a fine-grained naturalistic cohort study

Date Added
September 2nd, 2026
PRO Number
Pro00152573
Researcher
Matthew Carpenter

List of Studies


Keywords
Smoking
Summary

This is a research study to understand patterns of nicotine pouch use over time among three separate groups of people who: 1) co-use nicotine pouches and cigarettes, 2) co-use nicotine pouches and conventional smokeless tobacco (including chewing tobacco, dip, moist snuff, or snus), or 3) exclusively use nicotine pouches. This is a naturalistic survey study; there is nothing required or requested of participants other than to complete our surveys. Participants do not need to quit or reduce their pouch/smoking/smokeless tobacco product use if they do not want to. They do not need to travel for this study; it is completely remote, and they can participate from their home.
Participation in the study will take place over a period of 12 months in the form of: 1) Monthly Surveys (13 total), 2) Daily Diaries for the first 90 days, and 3) Follow-Up Diaries in each of the 7 days leading up to each monthly follow-up survey.

Institution
MUSC
Recruitment Contact
Avery Roberson
(843) 876-2441
robersav@musc.edu

A Virtual Mindfulness Program for Adults with Pulmonary Hypertension: Pilot Feasibility Testing and Implementation Strategy Development to Improve Quality of Life.

Date Added
September 1st, 2026
PRO Number
Pro00152432
Researcher
Tania Von Visger

List of Studies

Keywords
Education, Pulmonary Hypertension
Summary

This study aims to pilot test a virtual mindfulness meditation program for pulmonary hypertension (PH) in preparation for larger testing. Individuals living with PH will be invited to learn mindfulness practices via videos and the MMPH app for 8 weeks.

They will provide feedback via surveys at four time points: before and after the intervention (PAHSS, EmPHass-10, PHQ-8, PCL-5, CAMS-R), and again 1 month and 2 months after. They will be asked to wear a wrist actigraphy device before and after the intervention.

Participants will provide their feedback via an interview about their experience after the intervention is complete.

Institution
MUSC
Recruitment Contact
Tania Von Visger
6148226637
vonvisge@musc.edu

Improving Engagement in Post-Injury Mental Health Care Through Community Health Worker-Enhanced Trauma Recovery Services

Date Added
September 1st, 2026
PRO Number
Pro00152341
Researcher
Theresa Skojec

List of Studies

Keywords
Mental Health
Summary

This study is evaluating a program designed to support adults recovering from a traumatic injury, such as a motor vehicle crash, fall, or other serious injury. Recovery after an injury can be challenging, particularly for people who are experiencing emotional distress as well as difficulties with needs such as housing, food, transportation, or finances. The program, called TRRP+, combines mental health support with assistance from a Community Health Worker who can help participants identify needs, connect with available resources, and navigate services during their recovery. The study will include approximately 100 adults who have experienced a traumatic injury and report emotional distress and at least one unmet social need.
Researchers will examine whether TRRP+ is practical and helpful for patients and will gather feedback from participants, Community Health Workers, and trauma center staff about their experiences with the program. The information learned from this study will help researchers understand how programs like TRRP+ can better support patients' emotional, social, and practical needs as they recover from a traumatic injury.

Institution
MUSC
Recruitment Contact
Sarah German
843-792-0979
germansa@musc.edu

Development of a Multiple Health Behavior Change Intervention for Weight Loss and Smoking Cessation for Pre-Bariatric Surgery Patients

Date Added
September 1st, 2026
PRO Number
Pro00152089
Researcher
Caitlin Smith

List of Studies

Keywords
Obesity, Smoking
Summary

The purpose of this research study is to develop a multiple health behavior change intervention for weight loss and smoking cessation using medication (Naltrexone/Bupropion) and behavior therapy for adults considering bariatric surgery. All participants will receive the intervention (medication + behavior therapy) for four months. Participants will complete an interview at the end of treatment, which will be used to improve the intervention.

Institution
MUSC
Recruitment Contact
Caitlin Smith
843-876-0453
smithcai@musc.edu

Flavored ready-to-drink alcohol restriction in young adults: Behavioral and biomarker outcomes through a cancer prevention and biology collaborative

Date Added
September 1st, 2026
PRO Number
Pro00151811
Researcher
Roberta Freitas-Lemos

List of Studies

Keywords
Alcohol, Cancer/Other, Healthy Volunteer Studies, Substance Use
Summary

A research study at the Medical University of South Carolina is looking at young adults' experiences with alcohol and e-cigarette use during a 4-week study. The study is enrolling adults ages 21 to 29 who use flavored ready-to-drink alcoholic beverages and e-cigarettes. Participants will complete in-person study visits, brief daily electronic diaries, questionnaires, and provide blood and urine samples for research testing. Some participants will be asked to avoid flavored ready-to-drink alcoholic beverages for 2 weeks, while others will continue their usual use. The purpose of the study is to learn whether this type of short-term study procedure is feasible and acceptable, and to better understand patterns of alcohol and e-cigarette use among young adults.

Institution
MUSC
Recruitment Contact
Kaleigh Isgett
843-792-8357
carolinabovo@vt.edu

Olfaction and Neurodegenerative Disease

Date Added
September 1st, 2026
PRO Number
Pro00150356
Researcher
Rodney Schlosser

List of Studies


Keywords
Alzheimers, Dementia, Healthy Volunteer Studies, Non-interventional, Nose, Parkinsons
Summary

Smell loss has been found to be associated with mortality and neurodegenerative diseases. Unfortunately, there are no current biomarkers for olfactory loss and no specific mechanism to explain exactly how this association occurs. This study aims to uncover more about smell loss and its association with neurodegenerative disease such as Parkinson's disease, Alzheimer's disease, Multiple Sclerosis, and Mild Cognitive Impairment in the early/mild stages of those conditions. Study procedures involve questionnaires, a 40-item scratch and sniff smell test, assessment of cognitive function, blood sample, and nasal mucus and cell samples collected by a physician.

Institution
MUSC
Recruitment Contact
Mickey Lee
843-792-9496
sinus-research@musc.edu



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