Evaluation of a Text Message-Based Approach to Depression Screening Among Cancer Survivors

Date Added
March 18th, 2025
PRO Number
Pro00142039
Researcher
Evan Graboyes

List of Studies


Keywords
Cancer, Depression
Summary

Depression is common among cancer survivors but current screening approaches are not adequate. To help develop better strategies to screen for depression among cancer survivors, we will conduct a pilot randomized controlled trial with cancer survivors to evaluate whether a text message based approach to depression screening is feasible, acceptable, and potentially more effective than existing standard of care approaches to depression screening among cancer survivors.

Institution
MUSC
Recruitment Contact
Abigail Drake
843-670-9395
abd300@musc.edu

Evaluation of a Text Message-Based Approach to Depression Screening Among Cancer Survivors

Date Added
March 18th, 2025
PRO Number
Pro00142039
Researcher
Evan Graboyes

List of Studies


Keywords
Cancer, Depression
Summary

Depression is common among cancer survivors but current screening approaches are not adequate. To help develop better strategies to screen for depression among cancer survivors, we will conduct a pilot randomized controlled trial with cancer survivors to evaluate whether a text message based approach to depression screening is feasible, acceptable, and potentially more effective than existing standard of care approaches to depression screening among cancer survivors.

Institution
MUSC Health Chester Medical Center
Recruitment Contact
Abigail Drake
843-670-9395
abd300@musc.edu

Evaluation of a Text Message-Based Approach to Depression Screening Among Cancer Survivors

Date Added
March 18th, 2025
PRO Number
Pro00142039
Researcher
Evan Graboyes

List of Studies


Keywords
Cancer, Depression
Summary

Depression is common among cancer survivors but current screening approaches are not adequate. To help develop better strategies to screen for depression among cancer survivors, we will conduct a pilot randomized controlled trial with cancer survivors to evaluate whether a text message based approach to depression screening is feasible, acceptable, and potentially more effective than existing standard of care approaches to depression screening among cancer survivors.

Institution
MUSC Health Florence Medical Center
Recruitment Contact
Abigail Drake
843-670-9395
abd300@musc.edu

Evaluation of a Text Message-Based Approach to Depression Screening Among Cancer Survivors

Date Added
March 18th, 2025
PRO Number
Pro00142039
Researcher
Evan Graboyes

List of Studies


Keywords
Cancer, Depression
Summary

Depression is common among cancer survivors but current screening approaches are not adequate. To help develop better strategies to screen for depression among cancer survivors, we will conduct a pilot randomized controlled trial with cancer survivors to evaluate whether a text message based approach to depression screening is feasible, acceptable, and potentially more effective than existing standard of care approaches to depression screening among cancer survivors.

Institution
MUSC Health Lancaster Medical Center
Recruitment Contact
Abigail Drake
843-670-9395
abd300@musc.edu

Evaluation of a Text Message-Based Approach to Depression Screening Among Cancer Survivors

Date Added
March 18th, 2025
PRO Number
Pro00142039
Researcher
Evan Graboyes

List of Studies


Keywords
Cancer, Depression
Summary

Depression is common among cancer survivors but current screening approaches are not adequate. To help develop better strategies to screen for depression among cancer survivors, we will conduct a pilot randomized controlled trial with cancer survivors to evaluate whether a text message based approach to depression screening is feasible, acceptable, and potentially more effective than existing standard of care approaches to depression screening among cancer survivors.

Institution
MUSC Health Marion Medical Center
Recruitment Contact
Abigail Drake
843-670-9395
abd300@musc.edu

Evaluation of a Text Message-Based Approach to Depression Screening Among Cancer Survivors

Date Added
March 18th, 2025
PRO Number
Pro00142039
Researcher
Evan Graboyes

List of Studies


Keywords
Cancer, Depression
Summary

Depression is common among cancer survivors but current screening approaches are not adequate. To help develop better strategies to screen for depression among cancer survivors, we will conduct a pilot randomized controlled trial with cancer survivors to evaluate whether a text message based approach to depression screening is feasible, acceptable, and potentially more effective than existing standard of care approaches to depression screening among cancer survivors.

Institution
MUSC Health Kershaw Medical Center
Recruitment Contact
Abigail Drake
843-670-9395
abd300@musc.edu

Evaluation of a Text Message-Based Approach to Depression Screening Among Cancer Survivors

Date Added
March 18th, 2025
PRO Number
Pro00142039
Researcher
Evan Graboyes

List of Studies


Keywords
Cancer, Depression
Summary

Depression is common among cancer survivors but current screening approaches are not adequate. To help develop better strategies to screen for depression among cancer survivors, we will conduct a pilot randomized controlled trial with cancer survivors to evaluate whether a text message based approach to depression screening is feasible, acceptable, and potentially more effective than existing standard of care approaches to depression screening among cancer survivors.

Institution
MUSC Health Columbia Medical Center
Recruitment Contact
Abigail Drake
843-670-9395
abd300@musc.edu

A Multicenter Randomized Trial of EBUS-TBNA versus Transbronchial Mediastinal Cryobiopsy for Adequacy of Next Generation Sequencing: FROSTBITE-3

Date Added
March 18th, 2025
PRO Number
Pro00140380
Researcher
Christopher Gilbert

List of Studies

Keywords
Cancer, Lung, Pulmonary
Summary

This study is for patients scheduled for a bronchoscopy, a procedure that allows doctors to examine lungs and airways for evaluation of suspicious lung nodules. Those who give consent to participate in this study will be randomized into one of two lung biopsy sampling method groups based on the Rapid On Site Evaluation of the initial sample obtained by the doctor performing the bronchoscopy as part of the standard of care procedure for the patient. the potential groups the subject will be randomized into are: Cryoprobe or transbronchial biopsy needle. These devices are used with a bronchoscope to obtain lung tissue biopsy samples and are being evaluated to determine which is better for confirming a diagnosis. All procedures will be done via standard of care and screening will be accomplished via medical chart review. 7 days following the procedure, a member of the study team will check the subjects medical chart to assess whether any adverse events have occurred.

Institution
MUSC
Recruitment Contact
Michael Balassone
843-792-6696
Balassom@musc.edu

Randomized Phase III Study of Mosunetuzumab vs. Rituximab for low Tumor Burden Follicular Lymphoma

Date Added
March 6th, 2025
PRO Number
Pro00142136
Researcher
Brian Hess

List of Studies


Keywords
Cancer, Cancer/Lymphoma, Drug Studies, Men's Health, Women's Health
Summary

This study is for subjects diagnosed with follicular lymphoma. The purpose of this study is to assess if treatment with Mosunetuzumab can improve long term remission in patients with low tumor burden follicular lymphoma compared to rituximab. The treatment period for the Rituximab arm is approximately 40 weeks. The treatment period for the Mosunetuzumab arm is approximately 24 weeks. However the subject may remain in the study for up to 10 years for the follow-up period.

Institution
MUSC
Recruitment Contact
HCC Clinical Trials Office
843-792-9321
hcc-clinical-trials@musc.edu

An Open Label, Randomized, Controlled, Global Phase 3 Study Comparing ABBV-400 Monotherapy to LONSURF (Trifluridine and Tipiracil) plus Bevacizumab in Subjects with c-Met Over-Expressed Refractory Metastatic Colorectal Cancer

Date Added
February 25th, 2025
PRO Number
Pro00141996
Researcher
Toros Dincman

List of Studies

Keywords
Cancer, Drug Studies, Men's Health, Women's Health
Summary

The purpose of this study is to evaluate investigational treatments (study drug) in people with subjects with c-Met over-expressed refractory metastatic colorectal cancer

The purpose of this study is to determine the recommended ABBV-400 dose when ABBV-400 is given alone (monotherapy) in Stage 1, and to assess if ABBV-400 monotherapy is a safe and effective treatment compared to the standard of care (SOC) LONSURF [Trifluridine and Tipiracil] plus Bevacizumab in subjects with c-Met overexpressed (level of c-Met protein in your tumor cells is increased) uncontrolled metastatic colorectal cancer in Stage 2 of the study plan.

This is a phase 3 study; ABBV-400 is not FDA approved by the U.S. Food and Drug Administration (FDA). Treatment for this study may be up to 3 years. The procedures include taking study drug intravenously, blood and urine samples, MUGA scans and CT scans. Risks include diarrhea, nausea, vomiting, anemia, muscle aches, and joint pain. You may or may not receive a direct benefit from participating in this trial, however, information learned from the trial may help other people in the future.

Institution
MUSC
Recruitment Contact
HCC Clinical Trials Office
843-792-9321
hcc-clinical-trials@musc.edu



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