This study is for women who have endometrial cancer which has grown or has returned after earlier treatment. The purpose of the study is to see if by giving a combination of two experimental drugs or one experimental drug rather than the usual approach can lower the chance of the endometrial cancer growing or spreading by giving a combination of two experimental drugs or one experimental drug rather than the usual approach.

This study is for subjects that have been diagnosed with advanced solid cancer tumors or relapsed prostate cancer. The investigational drugs in this study are hydroxychloroquine, nelfinavir, metformin, dasatinib and sirolimus. The purpose of this study is to determine the safety and effectiveness of up to 5 study drugs used together for the treatment of cancer. Subjects can expect to be in this study for about 2.5 years.