Synergistic Interplay of Systemic Lupus Erythematosus (SLE) and Hypertension (HTN)

Date Added
January 13th, 2023
PRO Number
Pro00122811
Researcher
Justin Van Beusecum

List of Studies

Keywords
Healthy Volunteer Studies, Hypertension/ High Blood Pressure, Lupus, Women's Health
Summary

This study is to explore the relationship between lupus and hypertension (high blood pressure). Female volunteers between the ages of 18-65 are needed who meet 1 of 4 possible participation types: 1. Participants with diagnosis of lupus and hypertension, 2.Participants with lupus without hypertension, 3.Participants without lupus but have hypertension, or 4. Participants that have no lupus diagnosis or hypertension.

Study participation includes a 1 time visit to the Research Nexus and involves a review of currently available medical records and a brief participant questionnaire specific to demographics and behaviors. The study visit includes a series of 3 blood pressure readings and a blood collection of approximately 2 tablespoons of blood. Compensation is available.

Institution
MUSC
Recruitment Contact
Jonathan Flume
843-792-3926
jof63@musc.edu

A Prospective, Multicenter, Randomized, Open-Label Study to Evaluate the Efficacy and Safety of PMX Cartridge in Addition to Standard Medical Care for Patients with Endotoxemic Septic Shock

Date Added
December 7th, 2022
PRO Number
Pro00122530
Researcher
Blaithin McMahon

List of Studies


Keywords
Blood Disorders, Hypertension/ High Blood Pressure, Infectious Diseases, Kidney
Summary

The purpose of this study is to compare the safety and efficacy of the PMX cartridge ( Toramyxin) (in Addition to Standard Medical Care for Patients with Endotoxemic Septic Shock:
Eligible and consented subjects will be randomized to receive either the PMX cartridge (administered twice for 1½ to 2 hours per treatment session approximately 24 hours apart) plus standard medical care or standard medical care alone. For all subjects in whom treatment has been initiated, a follow-up visit (if they are still in the hospital) or a telephone call will be completed at Day 28 (or later) to determine their mortality status. In surviving subjects, a follow-up visit or telephone call to determine their mortality status will also take place at approximately three months (i.e. Day 90) and 12 months after the subject was randomized.

Institution
MUSC
Recruitment Contact
Marcie Pregulman
843-792-8166
pregulma@musc.edu

Telehealth-Enhanced Assessment and Management after Stroke-Blood Pressure (TEAMS-BP)

Date Added
October 20th, 2022
PRO Number
Pro00124260
Researcher
Christine Holmstedt

List of Studies


Keywords
Hypertension/ High Blood Pressure, Stroke, Stroke Recovery
Summary

This study will involve participating in one of two interventions to help adult patients who have had a stroke control their blood pressure: 1) an Intensive Clinic Management model (also called ICM), that includes clinic visits and health education versus 2) an Intensive Tailored Telehealth Management model (also called ITTM) that includes individualized care planning, health coaching, and referrals to needed community resources. Participation includes about 4 study visits over a period of 16 weeks, which will be performed during in-person clinic visits, through video call, or over the phone. Participants will be compensated for their time and participation in this research study.

Institution
MUSC
Recruitment Contact
Todd LeMatty
(843) 792-8538
lematty@musc.edu

Sickle Cell Disease Patient Registry

Date Added
August 23rd, 2022
PRO Number
Pro00122740
Researcher
Cathy Melvin

List of Studies