The Effects of Testosterone Replacement Therapy on the Fundamental Frequencies of Postmenopausal Women.

Date Added
April 11th, 2024
PRO Number
Pro00133858
Researcher
Stephanie Horton

List of Studies

Keywords
Aging, Hormones, Obstetrics and Gynecology, Throat
Summary

The purpose of this study is to measure the effects of hormone replacement therapy (HRT) on the female voice. Female individuals who are receiving hormone replacement therapy, which includes testosterone therapy, will be eligible to participate. We will track the pitch of these individuals' speaking voices during HRT in attempts to see whether HRT, specifically testosterone, can lead to changes in womens' speaking voices. We will be recruiting participants who have already received approx 6-9 months of HRT and compare these to age-matched individuals not receiving HRT. This is a cross-sectional study and we will give participants the option of continued follow-up for 9 more months to assess whether there are longer-term voice changes secondary to HRT. This could provide patients and medical providers with more information regarding the risks/benefits of pursuing hormone replacement therapy.

Institution
MUSC
Recruitment Contact
Stephanie Horton
843-996-6061
hortonst@musc.edu

3D MRA Fusion for Uterine Fibroid Embolization: A Randomized Controlled Trial

Date Added
March 5th, 2024
PRO Number
Pro00133923
Researcher
Marcelo Guimaraes

List of Studies


Keywords
Obstetrics and Gynecology, Women's Health
Summary

The study aims to investigate the impact of Magnetic Resonance Angiography (MRA) fusion on the safety and efficiency of Uterine Fibroid Embolization (UFE). UFE is a medical procedure used to treat uterine fibroids. MRA fusion provides a detailed three-dimensional roadmap of blood vessels in the pelvis during the procedure. This technology has the potential to reduce radiation exposure, procedure time, and contrast volume. .

Institution
MUSC
Recruitment Contact
Derek Groskreutz
8432437260
groskreu@musc.edu

The efficacy and safety of a CCT-102 regimen versus expectant management in the treatment of first trimester pregnancy loss

Date Added
January 23rd, 2024
PRO Number
Pro00133752
Researcher
Angela Dempsey-Fanning

List of Studies


Keywords
Obstetrics and Gynecology
Summary

The purpose of this study is to determine the efficacy and safety of a treatment regimen on women who have been diagnosed with a first trimester pregnancy loss. Women enrolled will be randomized to taking medication or expectant management.

Institution
MUSC
Recruitment Contact
Jesslyn Payne
843-792-7525
paynej@musc.edu

Leveraging Technology to Reduce Disparities and Improve Early Detection of and Timely Care for Postpartum Complications

Date Added
November 7th, 2023
PRO Number
Pro00130902
Researcher
Constance Guille

List of Studies


Keywords
Mental Health, Minorities, Obstetrics and Gynecology, Post Partum Depression, Pregnancy, Psychiatry, Women's Health
Summary

The purpose of the study is to learn if a program for newborn mom's can improve detection of complications after delivery and help women get medical care quickly and easily. Participants will be asked to complete a survey at the time of enrollment and at 4 additional times. All surveys can be completed via cell-phone or email. All women will be followed for 1-year after delivery. Women that enroll will be assigned to one of two groups: usual in person care OR usual in-person care PLUS a text message-based program that will ask about sign and symptoms of complications that may occur after delivery. If there is a concern, a care coordinator will call on the phone to discuss options and help refer to care if needed. Participants will be paid for their time in completing surveys.

Institution
MUSC
Recruitment Contact
Ellen Gomez
843-998-5635
gomezel@musc.edu

A Phase 2a/b, Randomized, Double-blind, Placebo-controlled, Parallel Group, Multicenter, Clinical Study to Evaluate the Efficacy and Safety of OG-6219 in 3 Dose Levels, in Women 18 to 49 Years of Age with Moderate to Severe Endometriosis-related Pain

Date Added
July 5th, 2023
PRO Number
Pro00129682
Researcher
David Soper

List of Studies


Keywords
Obstetrics and Gynecology
Summary

The purpose of this global study is to determine the efficacy, safety, and tolerability of 3 dose levels of OG-6219 (50, 100, and 150 mg twice a day [BID]) in pre-menopausal women between 18 and 49 years of age (inclusive), who have moderate to severe endometriosis-related pain.

Institution
MUSC
Recruitment Contact
Jesslyn Payne
843-792-7525
paynej@musc.edu

PCORI 1: Improving Maternal Mental Health & Substance Use Disorder Screening and Treatment

Date Added
November 1st, 2022
PRO Number
Pro00123833
Researcher
Constance Guille

List of Studies


Keywords
Depression, Mental Health, Obstetrics and Gynecology, Post Partum Depression, Pregnancy, Psychiatry, Substance Use, Women's Health
Summary

The purpose of the study is to compare a text message based mental health and substance use screening and referral to treatment program, called Listening to Women and Pregnant and Postpartum People (LTWP), to standard of care in-person mental health and substance use screening to look at rates of treatment attendance and retention in treatment. Participation would involve completing online surveys. You may be eligible to participate if you are age 18-45 years, are pregnant and entering prenatal care in one of MUSC's OB clinics, and attended a prenatal appointment at an MUSC clinic.

Institution
MUSC
Recruitment Contact
Edie Douglas
843-792-5958
douglaed@musc.edu

PCORI 1: Improving Maternal Mental Health & Substance Use Disorder Screening and Treatment

Date Added
November 1st, 2022
PRO Number
Pro00123833
Researcher
Constance Guille

List of Studies


Keywords
Depression, Mental Health, Obstetrics and Gynecology, Post Partum Depression, Pregnancy, Psychiatry, Substance Use, Women's Health
Summary

The purpose of the study is to compare a text message based mental health and substance use screening and referral to treatment program, called Listening to Women and Pregnant and Postpartum People (LTWP), to standard of care in-person mental health and substance use screening to look at rates of treatment attendance and retention in treatment. Participation would involve completing online surveys. You may be eligible to participate if you are age 18-45 years, are pregnant and entering prenatal care in one of MUSC's OB clinics, and attended a prenatal appointment at an MUSC clinic.

Institution
MUSC Health Florence Medical Center
Recruitment Contact
Edie Douglas
843-792-5958
douglaed@musc.edu

PCORI 1: Improving Maternal Mental Health & Substance Use Disorder Screening and Treatment

Date Added
November 1st, 2022
PRO Number
Pro00123833
Researcher
Constance Guille

List of Studies


Keywords
Depression, Mental Health, Obstetrics and Gynecology, Post Partum Depression, Pregnancy, Psychiatry, Substance Use, Women's Health
Summary

The purpose of the study is to compare a text message based mental health and substance use screening and referral to treatment program, called Listening to Women and Pregnant and Postpartum People (LTWP), to standard of care in-person mental health and substance use screening to look at rates of treatment attendance and retention in treatment. Participation would involve completing online surveys. You may be eligible to participate if you are age 18-45 years, are pregnant and entering prenatal care in one of MUSC's OB clinics, and attended a prenatal appointment at an MUSC clinic.

Institution
MUSC Health Lancaster Medical Center
Recruitment Contact
Edie Douglas
843-792-5958
douglaed@musc.edu

Glycemic Profile in At Risk Women Without Diabetes and Macrosomic Fetuses

Date Added
July 19th, 2022
PRO Number
Pro00121993
Researcher
Matthew Finneran

List of Studies


Keywords
Obstetrics and Gynecology
Summary

This study is to collect data to assess the benefit of 3rd trimester glucose surveillance in non-diabetic women with big babies.

Institution
MUSC
Recruitment Contact
Jesslyn Payne
843-792-7525
paynej@musc.edu

A Randomized Controlled Trial of Women Involved in Supporting Health (WISH), a Peer-Led Intervention to Improve Postpartum Retention in HIV Care

Date Added
April 18th, 2022
PRO Number
Pro00118631
Researcher
Gweneth Lazenby

List of Studies


Keywords
Obstetrics and Gynecology
Summary

The purpose of the study is to learn more about programs that can improve the health and wellbeing of mothers and their babies during the period after delivery. Women living with HIV experience diverse health problems in the period directly after delivery.

Institution
MUSC
Recruitment Contact
Jesslyn Payne
843-792-7525
paynej@musc.edu



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