A Qualitative Investigation of Patient, Family, and Provider Treatment Preferences in PTSD and Alcohol Use Disorder

Date Added
April 1st, 2025
PRO Number
Pro00142158
Researcher
Sarah Giff

List of Studies

Keywords
Alcohol, Anxiety, Military, Psychiatry, Stress Disorders, Substance Use
Summary

Co-occurring post-traumatic stress disorder (PTSD) and alcohol use disorder (AUD) disproportionately affects Veterans and has significant negative impacts on the safety, wellbeing, and quality of life of Veterans, their romantic partners, and their families. However, treatments that address co-occurring PTSD-AUD and restore Veterans' psychosocial functioning are lacking. This project is designed to learn more to facilitate improving treatment approaches aimed at reducing symptoms of co-occurring PTSD-AUD and improving functioning among Veterans and their partners. The goal of this project is to learn from Veterans, family members, and treatment providers in order to inform an adaptation of a brief dyadic AUD intervention to be delivered alongside integrated PTSD-AUD treatment for Veteran couples.

Institution
MUSC
Recruitment Contact
Sarah Giff
(843) 792-5569
giff@Musc.edu

3D CTA Fusion for Prostate Artery Embolization: A Randomized Controlled Trial

Date Added
April 1st, 2025
PRO Number
Pro00140426
Researcher
Stephen Stringfellow

List of Studies

Keywords
Men's Health
Summary

This research study is focused on evaluating the effectiveness of a new imaging technique for a procedure called Prostate Artery Embolization (PAE), which is used to treat an enlarged prostate. The study compares two groups of patients: one group receives PAE with advanced imaging called 3D CTA fusion, and the other group receives PAE using the standard imaging method. The goal is to determine if using 3D CTA fusion can make the procedure faster, reduce the amount of radiation exposure, and decrease the need for contrast dye during the procedure. By studying these two groups, researchers hope to identify ways to make PAE safer and more efficient​

Institution
MUSC
Recruitment Contact
Derek Groskreutz
8432437260
groskreu@musc.edu

Operant conditioning of the wrist extensor motor evoked potential to target corticospinal plasticity and upper limb motor recovery after cervical spinal cord injury

Date Added
April 1st, 2025
PRO Number
Pro00138869
Researcher
Allison Lewis

List of Studies

Keywords
Central Nervous System, Nervous System, Rehabilitation Studies, Spinal Cord
Summary

Individuals with chronic cervical spinal cord injury will complete a 10-week training protocol where they receive non-invasive brain stimulation and feedback on the size of the corresponding muscle response (wrist extensor). We will assess the impact of the brain stimulation training on 1) the brain-to-spinal cord-to-muscle connection and 2) motor functions of the arm and hand. Also, brain and spine magnetic resonance imaging will be collected before and after the training. The imaging measurements will tell us about how spinal damage, brain function, and brain structure relate to motor presentation and the response to the training.

Institution
MUSC
Recruitment Contact
Blair Dellenbach
843-792-6313
stecb@musc.edu

Advancing the Evidence for Hospital Violence Intervention Programs (HVIPs) in the Southeast: Qualitative Assessment of Patient and Caregiver Experiences After Firearm Injury

Date Added
March 24th, 2025
PRO Number
Pro00141320
Researcher
Ashley Hink

List of Studies

Keywords
Critical Care
Summary

The purpose of the study is to assess healthcare interactions and violence intervention services provided to patients and their loved ones that are treated for firearm injuries. This will be done in a 30 to 45-minute interview where participants will be asked questions about their healthcare experience, services provided by the Turning the Tide Violence Intervention Program (TTVIP), what went well with their care and services, and what could be improved. This information will be used to better understand the experiences and needs of patients and families that experience a violent injury, what is done well by trauma centers and hospital violence intervention programs (HVIPs), and what could be improved in their experience and recovery.

Institution
MUSC
Recruitment Contact
Claire Jacoby
8437691689
jacobyc@musc.edu

Complex verb-learning situations

Date Added
March 19th, 2025
PRO Number
Pro00142589
Researcher
Sabrina Horvath

List of Studies

Keywords
Children's Health, Healthy Volunteer Studies, Language
Summary

Children ages 3-4.5 years of age will watch videos designed to teach them made-up verbs. Then, they will be tested on whether they were able to learn the made-up verbs that were presented to them. Findings from this study will help researchers better understand how children learn language and what word-learning situations are easy or difficult for toddlers. This study will be conducted virtually using video conferencing software.

Institution
MUSC
Recruitment Contact
Sabrina Horvath
(843) 792-9363
horvaths@musc.edu

Dynamic motor cortical responses to subdural electrical stimulation.

Date Added
March 18th, 2025
PRO Number
Pro00142103
Researcher
Nathan Rowland

List of Studies


Keywords
Parkinsons
Summary

Current surgical treatments for Parkinson's disease have associated risks that may prevent patients from being offered surgery called "deep brain stimulation" or DBS. This is mainly because electrodes have to be placed through brain tissue to reach the target. Stimulation at the surface of the brain might be a potential alternative, but current research has not shown consistent results, and this may be because the mechanism of action is not clear. In this study, we aim to stimulate and record the brain at the surface to help answer this question and potentially improve the consistency and effectiveness of this treatment.

Institution
MUSC
Recruitment Contact
M S Zobaer
8329557191
zobaer@musc.edu

Evaluation of a Text Message-Based Approach to Depression Screening Among Cancer Survivors

Date Added
March 18th, 2025
PRO Number
Pro00142039
Researcher
Evan Graboyes

List of Studies


Keywords
Cancer, Depression
Summary

Depression is common among cancer survivors but current screening approaches are not adequate. To help develop better strategies to screen for depression among cancer survivors, we will conduct a pilot randomized controlled trial with cancer survivors to evaluate whether a text message based approach to depression screening is feasible, acceptable, and potentially more effective than existing standard of care approaches to depression screening among cancer survivors.

Institution
MUSC
Recruitment Contact
Abigail Drake
843-670-9395
abd300@musc.edu

Evaluation of a Text Message-Based Approach to Depression Screening Among Cancer Survivors

Date Added
March 18th, 2025
PRO Number
Pro00142039
Researcher
Evan Graboyes

List of Studies


Keywords
Cancer, Depression
Summary

Depression is common among cancer survivors but current screening approaches are not adequate. To help develop better strategies to screen for depression among cancer survivors, we will conduct a pilot randomized controlled trial with cancer survivors to evaluate whether a text message based approach to depression screening is feasible, acceptable, and potentially more effective than existing standard of care approaches to depression screening among cancer survivors.

Institution
MUSC Health Chester Medical Center
Recruitment Contact
Abigail Drake
843-670-9395
abd300@musc.edu

Evaluation of a Text Message-Based Approach to Depression Screening Among Cancer Survivors

Date Added
March 18th, 2025
PRO Number
Pro00142039
Researcher
Evan Graboyes

List of Studies


Keywords
Cancer, Depression
Summary

Depression is common among cancer survivors but current screening approaches are not adequate. To help develop better strategies to screen for depression among cancer survivors, we will conduct a pilot randomized controlled trial with cancer survivors to evaluate whether a text message based approach to depression screening is feasible, acceptable, and potentially more effective than existing standard of care approaches to depression screening among cancer survivors.

Institution
MUSC Health Florence Medical Center
Recruitment Contact
Abigail Drake
843-670-9395
abd300@musc.edu

Evaluation of a Text Message-Based Approach to Depression Screening Among Cancer Survivors

Date Added
March 18th, 2025
PRO Number
Pro00142039
Researcher
Evan Graboyes

List of Studies


Keywords
Cancer, Depression
Summary

Depression is common among cancer survivors but current screening approaches are not adequate. To help develop better strategies to screen for depression among cancer survivors, we will conduct a pilot randomized controlled trial with cancer survivors to evaluate whether a text message based approach to depression screening is feasible, acceptable, and potentially more effective than existing standard of care approaches to depression screening among cancer survivors.

Institution
MUSC Health Lancaster Medical Center
Recruitment Contact
Abigail Drake
843-670-9395
abd300@musc.edu



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