The need to advance knowledge and increase access to treatment for co-occurring posttraumatic stress disorder (PTSD) and substance use disorders (SUD) is a priority for service members and Veterans. PTSD and SUD often co-occur and are two of the most common and debilitating mental health disorders among service members and Veterans. However, few providers are trained in this approach and therefore are not prepared to deliver best practice care to Veterans who need integrated PTSD/SUD treatment.
This project will directly address this critical gap in provider training to improve the care of Veterans with comorbid PTSD/SUD, by providing development and testing of a web-based provider training course for concurrent treatment of PTSD and SUD Using prolonged exposure (COPE).
The purpose of this study is to develop and test if upper limb task practice and muscle activity training improve upper limb function in stroke survivors. Participants will be asked to come to the laboratory 3 times a week for 6 weeks to receive upper limb task practice and/or muscle activity training. Participants will also come to the laboratory for additional 3 visits for assessments of upper extremity function. The total duration of the study will be 2.5 months.
Research shows that exercising at home can improve arm and hand movement after a stroke. Unfortunately, it can be hard to exercise enough to make a difference in arm and hand movement after stroke. In this study, we will try to determine things that make it easy or hard for Veterans to exercise their arm and hand after a stroke. In this study, we will recruit Veteran stroke survivors who have difficulty using their arm and hand after a stroke. First, we will administer surveys and questionnaires to get Veteran stroke survivors' perspectives on their self-confidence, mood, sleep, and more. Then, we will ask them to track their home exercise using a wearable movement tracker (like a smart watch). Then, Veteran stroke survivors will meet with a researcher to talk about their experience doing home exercise and why they think it was easy or hard to do.
Following stroke, communication between brain areas and to the lower limbs can be compromised, leading to impairments in walking ability. Paired associative stimulation (PAS), a method of non-invasive brain stimulation, is thought to be a useful tool in understanding the relationship between different parts of the brain, and functional ability. However, PAS protocols have not been optimized for use post-stroke. The purpose of this research study is to determine the reliability and effectiveness PAS. This study involve individuals >6 months after having a stroke.
The purpose of the study is to compare a text message based mental health and substance use screening and referral to treatment program, called Listening to Women and Pregnant and Postpartum People (LTWP), to standard of care mental health and substance use screening to look at treatment attendance and retention in treatment. Participation would involve completing the consent process and then the MUSC study team would collect mental health and substance use screening, referral and treatment data on participant's from their medical records or through the participant's pediatrician. The participant may also be asked to take part in surveys and interviews.
This study is being done to learn more about Lipoprotein(a) (Lp(a) values in people with known history of Atherosclerotic Cardiovascular Disease (ASCVD). Lipoprotein(a) is a particle that carries cholesterol in the blood. ASCVD is a type of thickening or hardening of the arteries caused by a build up of plaque in the walls of arteries. Plaque is made up of substances such as fats and cholesterol. Plaque can cause blockages in the arteries which could result in a heart attack. High levels of Lp(a) are directly associated with a higher risk of cardiovascular events such as heart attacks or aortic stenosis.
Participation in this study will last up to 2 weeks and involve data collection and a blood draw for a Lipoprotein(a) level unless you've had a level checked in the past. You will be informed of your Lipoprotein(a) level.
This study is for women with inflammatory breast cancer. This study is being done to see if by adding the drug olaparib to the usual radiation therapy will lower the chance of their cancer returning.
This study will involve participating in one of two interventions to help adult patients who have had a stroke control their blood pressure: 1) an Intensive Clinic Management model (also called ICM), that includes clinic visits and health education versus 2) an Intensive Tailored Telehealth Management model (also called ITTM) that includes individualized care planning, health coaching, and referrals to needed community resources. Participation includes about 4 study visits over a period of 16 weeks, which will be performed during in-person clinic visits, through video call, or over the phone. Participants will be compensated for their time and participation in this research study.
We are studying whether visual field testing can be completed using a virtual reality headset with software designed and installed to cause a "blink to threat" response. A positive "blink to threat" response implies an intact visual field. Subject volunteers will have both in person "blink to threat" visual field testing and headset "blink to threat" visual field testing. We are testing the accuracy, timing, tolerability and satisfaction (of both examiner and patient) with the use of virtual reality visual field testing.