Age effects on cochlear reflectance in adult humans Save

Date Added
February 13th, 2017
PRO Number
Pro00061210
Researcher
Sara Fultz
Keywords
Aging, Ears, Geriatrics, Healthy Volunteer Studies, Hearing, Minorities
Summary

This project, funded by the National Institutes of Health, is being conducted to learn how structures of the middle-ear and inner ear are affected by age and hearing ability, and to provide a scientific basis for diagnosis and rehabilitation of hearing loss. Volunteers who meet the eligibility requirements may enroll in this study, which will include measurements of hearing using several procedures. Participants 18 years of age and older with normal hearing or hearing loss are currently being recruited. One or two visits of 1.5 to 2 hours are required and scheduling is flexible. Compensation for time will be provided and parking validated.

Institution
MUSC
Recruitment Contact
Sara Fultz
843-792-0667
fultzs@musc.edu

Reference Range Study for the Quantra Analyzer with the Quantra Surgical Cartridge Save

Date Added
February 1st, 2017
PRO Number
Pro00060875
Researcher
Charles Greenberg
Keywords
Healthy Volunteer Studies
Summary

This study will determine reference range limits for the Quantra Hemostasis Analyzer, which is a new type of lab testing device designed to help doctors manage bleeding during surgery. Healthy adult volunteers will have a brief study visit and donate a small amount of blood for the study. Compensation will be provided.

Institution
MUSC
Recruitment Contact
Lauren Card
843-792-5935
cardl@musc.edu

Operant conditioning of spinal reflexes in healthy people and people with neurological disorders. Save

Date Added
November 23rd, 2016
PRO Number
Pro00060769
Researcher
Richard Segal
Keywords
Body Composition, Healthy Volunteer Studies, Movement Disorders, Muscle, Nerve, Nervous System, Physical Therapy, Rehabilitation Studies, Stroke, Stroke Recovery
Summary

Our long term goal is to enhance the locomotion of impaired individuals after a neurological injury.
We are trying to recruit as healthy control participants, and neurologically impaired individuals (incomplete SCI and after-stroke patients) to participate in this study.
For neurologically impaired individuals a physical therapist will complete IRB approved questionnaires to measure your mobility, muscle strength, balance, walking speed, and distance.
All participants will meet with study staff who would then test your reflexes by placing some superficial skin based electrodes behind the knee and apply mild stimulation while standing/sitting.
If enrolled, you may be required to participate for 30 sessions (3 sessions/week), each lasting about one hour over a period of 3 months. Compensation is available for your participation.

Institution
MUSC
Recruitment Contact
Aviroop Dutt-Mazumder
843-792-0275
duttamaz@musc.edu

Establishing a Baseline Health Assessment in Economically Distressed Communities of North Charleston, SC Save

Date Added
November 14th, 2016
PRO Number
Pro00056615
Researcher
Michelle Nichols
Keywords
Environmental Factors, Healthy Volunteer Studies
Summary

Health outcomes resulting from chronic exposures to port activities include increased cancer, diabetes, cardiovascular disease, and respiratory disease. The proposed research is significant because it will allow adverse health effects of anticipated air pollutants resulting from increased diesel emissions associated with port activities to be assessed. The research team has developed with community input a health survey from existing, validated survey instruments to self-report health outcomes including cancer, diabetes, cardiovascular and lung diseases.

Institution
MUSC
Recruitment Contact
Michelle Nichols
843-792-1802
nicholmg@musc.edu

Gendered Racial Factors in Girls? Self-Regulation, Drug, and Behavior Disparities Save

Date Added
November 1st, 2016
PRO Number
Pro00060638
Researcher
Colleen Hallidayboykins
Keywords
Adolescents, Children's Health, Education, Healthy Volunteer Studies, Mental Health, Minorities, Substance Use, Women's Health
Summary

The purpose of this study is to understand factors contributing to managing emotions, behavior problems, and substance use risk among girls. Middle school adolescent girls will be asked about their thoughts and feelings about themselves and their ethnic group, perceptions, and discrimination. They will also report on their behavior and substance use risk. Their reactions to recent incidents of unfair treatment or disciplinary action will also be assessed.

Institution
MUSC
Recruitment Contact
Jennifer Powell
843-876-0567
smithjl@musc.edu

Neuroscience-Informed Treatment Development for Adolescent Alcohol Use Save

Date Added
October 4th, 2016
PRO Number
Pro00058771
Researcher
Lindsay Squeglia
Keywords
Adolescents, Alcohol, Brain, Drug Studies, Healthy Volunteer Studies, Pediatrics, Psychiatry, Substance Use
Summary

This study will examine the effect of N-Acetylcysteine (NAC), an over-the-counter antioxidant supplement on brains of youth (ages 15-19) using magnetic resonance imaging (MRI). 50 adolescents will receive, in a counterbalanced order, a 10-day course of NAC 1200 mg twice daily and a subsequent 10-day course of matched placebo twice daily, separated by 11 days. Urine and blood samples will be collected at baseline and urine samples again before and after each course of medication treatment. Participants will receive a 1- hour MRI scan at baseline and after each treatment trial.

You/your child could be eligible to participate if he or she is:
Between the ages of 15 and 19.
Has consumed alcohol.
Participants must provide informed consent and youth under 18 must have parental consent to participate.
Compensation is available to those who qualify.

Institution
MUSC
Recruitment Contact
Lindsay Meredith
(843) 792-7317
porteann@musc.edu

Further development and validation of the Community Culture Survey Save

Date Added
October 3rd, 2016
PRO Number
Pro00055736
Researcher
Patrick O'neil
Keywords
Healthy Volunteer Studies
Summary

The Community Culture Survey (CCS) was developed at the University of Hawai'i-Hilo as a measure of the impact of cultural influences on health. Preliminary data were collected to assess its validity and reliability. We are collecting similar data on a revised version of the CCS to assess its usefulness among more varied samples outside of Hawai'i.

Participants will be adults who complete a brief survey packet including the CCS and questions related to health and quality of life. Basic demographics will also be elicited (age, gender, etc). The survey packets will be completed by the respondent either with paper copies or an online survey site such as Survey Monkey. All responses will be anonymous; the online survey site will be set to anonymous to avoid capturing IP addresses.

Institution
MUSC
Recruitment Contact
Sarah Hales
8437922350
bridg@musc.edu

A Pilot Trial Investigating the Effect of Applying Low Field Magnetic Stimulation (LFMS) in Slow Wave Sleep on Electrographic (EEG) Power in Healthy Adults Save

Date Added
September 27th, 2016
PRO Number
Pro00059499
Researcher
Thomas Uhde
Keywords
Healthy Volunteer Studies
Summary

Participants aged 20-65 will be recruited for a study exploring the relationship between sleep and low field magnetic stimulation (LFMS), a novel and safe form of brain neurostimulation. Recruitment will be accomplished by posting advertisements on the MUSC broadcast messages and online media (e.g. craigslist). Those responding to the advertisements will undergo a brief phone screening where basic information about the study will be discussed, and to ensure that all inclusion and exclusion criteria are met. Those individuals who are both interested and meet criteria will meet with one of the investigators for an enrollment visit, during which time they will review and sign an informed consent document. If they continue to meet inclusion and exclusion criteria they will spend two nights in the sleep lab, separated by 4-10 days. On both occasions they will undergo an overnight sleep study and receive LFMS while they sleep.

Institution
MUSC
Recruitment Contact
Allison Wilkerson
8437924636
wilkersa@musc.edu

Charleston Area Parent and Teen Experiences with Race (CHAPTER) Study Save

Date Added
September 6th, 2016
PRO Number
Pro00058529
Researcher
Colleen Hallidayboykins
Keywords
Adolescents, Healthy Volunteer Studies, Mental Health, Minorities, Substance Use
Summary

The purpose of this study is to understand thoughts, experiences, emotions, and behaviors of African American teens and their families. African American teens and their families will be asked about their thoughts and feelings about themselves and their ethnic group, perceptions, and discrimination. They will also report on their behavior and substance use.

Institution
MUSC
Recruitment Contact
Jennifer Powell
843-876-0567
smithjl@musc.edu

Adapting Web-Based ASAP (Alcohol and Sexual Assault Prevention) for Veterans Save

Date Added
June 7th, 2016
PRO Number
Pro00053156
Researcher
Amanda Gilmore
Keywords
Alcohol, Healthy Volunteer Studies, Mental Health, Military, Substance Use, Women's Health
Summary

The goal of this study is to receive Veteran feedback on an intervention being developed for female Veterans to reduce their risk of alcohol misuse and sexual assault. We are recruiting 20 female Veterans who engage in alcohol misuse to receive feedback on the intervention content. Feedback will be integrated into the intervention prior to being used with female Veterans.

Institution
MUSC
Recruitment Contact
Amanda Gilmore
843-792-8348
gilmoram@musc.edu

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