Neural Determinants of Age-Related Change in Auditory-Visual Speech Processing Save

Date Added
September 24th, 2017
PRO Number
Pro00070971
Researcher
James Dias
Keywords
Aging, Brain, Central Nervous System, Ears, Healthy Volunteer Studies, Hearing, Language, Minorities, Vision/ Eye
Summary

Older adults typically have trouble identifying the speech they hear, especially in noisy environments. Fortunately, compared to younger adults, older adults are better able to compensate for difficulties identifying the speech they hear by recruiting the visual system. However, the extent to which older adults can benefit from visual input, and how this influence relates to age-related changes in brain structure and function, have not been thoroughly investigated. The general purpose of this study is to determine how age-related changes in brain structure and function affect how well people hear and see. This study seeks participants with normal hearing to mild hearing loss, who also have normal or corrected-to-normal vision.

Institution
MUSC
Recruitment Contact
James Dias
(843) 792-3921
diasj@musc.edu

Pilot study of mobile app monitoring to prevent heat-related symptoms among Hispanic farmworkers Save

Date Added
September 20th, 2017
PRO Number
Pro00069288
Researcher
John Luque
Keywords
Education, Environmental Factors, Healthy Volunteer Studies
Summary

The proposed research will test and evaluate a Spanish-language, heat-related
illness (HRI) prevention, OSHA mobile application (app) intervention (Heat Safety Tool) in South Carolina, with the long-term goal of reducing HRI among migrant and seasonal farmworkers.

Institution
MUSC
Recruitment Contact
Caroline Davila
843-876-2248
davilac@musc.edu

Patient Recall and Comprehension of Informed Consent for Surgical Procedures in Otolaryngology Save

Date Added
September 19th, 2017
PRO Number
Pro00064396
Researcher
Krishna Patel
Keywords
Healthy Volunteer Studies
Summary

This study will look at patients or caregivers who sign consent for surgical procedures to determine how well they remember key elements of the surgical consent. Participants will be identified from MUSC Otolaryngology (ENT) clinics. Any patient or caregiver for a patient for is scheduled to undergo a surgical procedure may be considered for the study. All potential subjects will undergo a pre-operative visit where all details of the surgery will be discussed and consent for surgery is signed. Potential subjects will be contacted by telephone between 3-10 days after the pre-operative visit. During this telephone call, subjects who would like to participate in the study are enrolled and complete a questionnaire over the phone regarding the information covered during the consent for surgery. Subjects will again be contacted between two to three weeks after the surgery to complete a satisfaction survey of the consent process. The data will be collected and stored in a secure database. Goals of the study are to evaluate patient or caregiver?s recall of details discussed during the surgical consent process, to identify factors that may influence patient or caregiver recall of details of the surgical consent, and to evaluate patient satisfaction with the consent process to determine areas for improvement.

Institution
MUSC
Recruitment Contact
Alexander Murphey
7068361987
murphey@musc.edu

The Effect of an External Trunk Perturbation on Landing Biomechanics Save

Date Added
September 6th, 2017
PRO Number
Pro00067459
Researcher
Kate Pfile
Keywords
Healthy Volunteer Studies
Summary

The purpose of this study is to look at the effect of an unexpected trunk movement during a jump landing on lower extremity joint movements and forces. Furthermore this study is examining the relationship between core muscle (abdomen, hip and low back muscles) function and hip and knee joint movements and forces during a jump landing.

Institution
MUSC
Recruitment Contact
Kate Pfile
843-953-3607
cofcresearchstudy@gmail.com

Age effects on cochlear reflectance in adult humans Save

Date Added
February 13th, 2017
PRO Number
Pro00061210
Researcher
Sara Fultz
Keywords
Aging, Ears, Geriatrics, Healthy Volunteer Studies, Hearing, Minorities
Summary

This project, funded by the National Institutes of Health, is being conducted to learn how structures of the middle-ear and inner ear are affected by age and hearing ability, and to provide a scientific basis for diagnosis and rehabilitation of hearing loss. Volunteers who meet the eligibility requirements may enroll in this study, which will include measurements of hearing using several procedures. Participants 18 years of age and older with normal hearing or hearing loss are currently being recruited. One or two visits of 1.5 to 2 hours are required and scheduling is flexible. Compensation for time will be provided and parking validated.

Institution
MUSC
Recruitment Contact
Sara Fultz
843-792-0667
fultzs@musc.edu

Reference Range Study for the Quantra Analyzer with the Quantra Surgical Cartridge Save

Date Added
February 1st, 2017
PRO Number
Pro00060875
Researcher
Charles Greenberg
Keywords
Healthy Volunteer Studies
Summary

This study will determine reference range limits for the Quantra Hemostasis Analyzer, which is a new type of lab testing device designed to help doctors manage bleeding during surgery. Healthy adult volunteers will have a brief study visit and donate a small amount of blood for the study. Compensation will be provided.

Institution
MUSC
Recruitment Contact
Lauren Card
843-792-5935
cardl@musc.edu

Operant conditioning of spinal reflexes in healthy people and people with neurological disorders. Save

Date Added
November 23rd, 2016
PRO Number
Pro00060769
Researcher
Richard Segal
Keywords
Body Composition, Healthy Volunteer Studies, Movement Disorders, Muscle, Nerve, Nervous System, Physical Therapy, Rehabilitation Studies, Stroke, Stroke Recovery
Summary

Our long term goal is to enhance the locomotion of impaired individuals after a neurological injury.
We are trying to recruit as healthy control participants, and neurologically impaired individuals (incomplete SCI and after-stroke patients) to participate in this study.
For neurologically impaired individuals a physical therapist will complete IRB approved questionnaires to measure your mobility, muscle strength, balance, walking speed, and distance.
All participants will meet with study staff who would then test your reflexes by placing some superficial skin based electrodes behind the knee and apply mild stimulation while standing/sitting.
If enrolled, you may be required to participate for 30 sessions (3 sessions/week), each lasting about one hour over a period of 3 months. Compensation is available for your participation.

Institution
MUSC
Recruitment Contact
Aviroop Dutt-Mazumder
843-792-0275
duttamaz@musc.edu

Establishing a Baseline Health Assessment in Economically Distressed Communities of North Charleston, SC Save

Date Added
November 14th, 2016
PRO Number
Pro00056615
Researcher
Michelle Nichols
Keywords
Environmental Factors, Healthy Volunteer Studies
Summary

Health outcomes resulting from chronic exposures to port activities include increased cancer, diabetes, cardiovascular disease, and respiratory disease. The proposed research is significant because it will allow adverse health effects of anticipated air pollutants resulting from increased diesel emissions associated with port activities to be assessed. The research team has developed with community input a health survey from existing, validated survey instruments to self-report health outcomes including cancer, diabetes, cardiovascular and lung diseases.

Institution
MUSC
Recruitment Contact
Michelle Nichols
843-792-1802
nicholmg@musc.edu

Gendered Racial Factors in Girls? Self-Regulation, Drug, and Behavior Disparities Save

Date Added
November 1st, 2016
PRO Number
Pro00060638
Researcher
Colleen Hallidayboykins
Keywords
Adolescents, Children's Health, Education, Healthy Volunteer Studies, Mental Health, Minorities, Substance Use, Women's Health
Summary

The purpose of this study is to understand factors contributing to managing emotions, behavior problems, and substance use risk among girls. Middle school adolescent girls will be asked about their thoughts and feelings about themselves and their ethnic group, perceptions, and discrimination. They will also report on their behavior and substance use risk. Their reactions to recent incidents of unfair treatment or disciplinary action will also be assessed.

Institution
MUSC
Recruitment Contact
Jennifer Powell
843-876-0567
smithjl@musc.edu

Neuroscience-Informed Treatment Development for Adolescent Alcohol Use Save

Date Added
October 4th, 2016
PRO Number
Pro00058771
Researcher
Lindsay Squeglia
Keywords
Adolescents, Alcohol, Brain, Drug Studies, Healthy Volunteer Studies, Pediatrics, Psychiatry, Substance Use
Summary

This study will examine the effect of N-Acetylcysteine (NAC), an over-the-counter antioxidant supplement on brains of youth (ages 15-19) using magnetic resonance imaging (MRI). 55 adolescents will receive, in a counterbalanced order, a 10-day course of NAC 1200 mg twice daily and a subsequent 10-day course of matched placebo twice daily, separated by 11 days. Urine samples will be collected at screening and urine and blood samples will be collected before and after each course of medication treatment. Participants will receive a 1- hour MRI scan at baseline and after each treatment trial.

You/your child could be eligible to participate if he or she is:
Between the ages of 15 and 19.
May or may not drink alcohol.
Participants must provide informed consent and youth under 18 must have parental consent to participate.
Compensation is available to those who qualify.

Institution
MUSC
Recruitment Contact
Anna Porter
(843) 792-7317
porteann@musc.edu

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