Neuromodulation of Cognitive Control Neurocircuits for Stroke Rehabilitation Save

Date Added
May 7th, 2019
PRO Number
Pro00086015
Researcher
Lisa Mcteague

List of Studies


Profiles_link
Keywords
Memory Loss, Stroke, Stroke Recovery
Summary

The goal of this study is to determine the pattern of cognitive impairment in chronic stroke, both in terms of performance during cognitive testing as well as brain neurocircuit activation.

Institution
MUSC
Recruitment Contact
Lisa McTeague
843-792-8274
mcteague@musc.edu

A Phase III, Multicenter, Randomized, Double-Blind, Placebo-COntrolled, Parallel-Group, Efficacy, and Safety Study of Gantenerumab in Patients with Early (Prodromal to Mild) Alzheimer's Disease Save

Date Added
November 27th, 2018
PRO Number
Pro00082763
Researcher
Nicholas Milano

List of Studies


Profiles_link
Keywords
Alzheimers, Memory Loss
Summary

This study will evaluate the efficacy and safety of gantenerumab compared with placebo in patients with early Alzheimer's Disease.

Study duration for each subject will include a 12 week screening period (including the optional prescreening period), followed by a double-blind treatment period of 102 weeks of study drug treatment plus a visit 2 weeks after the last dose (week 104), and followed by the post-double-blind treatment period of two follow-up visits at 14 and 50 weeks after the last dose (weeks 116 and 152 respectively). Thus for a patient not entering the OLE, the maximum length of study is approximately 164 weeks.

Institution
MUSC
Recruitment Contact
Aparna Choudhury
843-792-2845
Choudhur@MUSC.edu

Odor Disturbances: Clinical Care Registry Save

Date Added
September 26th, 2018
PRO Number
Pro00080333
Researcher
Thomas Uhde

List of Studies


Profiles_link
Keywords
ADD/ADHD, Adolescents, Aging, Allergy, Alzheimers, Anxiety, Asthma, Autism, Autoimmune disease, Central Nervous System, Chronic Fatigue, Depression, Environmental Factors, Fibromyalgia, Inflammation, Memory Loss, Nervous System, Parkinsons, Psychiatry
Summary

Candidates for this study may or may not report disturbances in odor perception as their primary reason for seeking treatment at MUSC. This study is designed to collect long term, observational data from patients who are being treated with routine clinical care in health clinics at MUSC. Data from clinical questionnaires will be de-identified and stored in a database.

Institution
MUSC
Recruitment Contact
Richard Simmons
843-792-7439
simmr@musc.edu

Connectome Biomarkers for Predicting Alzheimer's Risk in Traumatic Brain Injury Save

Date Added
July 17th, 2018
PRO Number
Pro00077915
Researcher
Jane Joseph

List of Studies


Profiles_link
Keywords
Aging, Alzheimers, Brain, Dementia, Healthy Volunteer Studies, Memory Loss, Military
Summary

Traumatic Brain Injury is a risk factor for Alzheimer's Disease and other dementias. This study will use neuroimaging in Veterans and civilians with a history of TBI or without TBI to understand whether some of the brain changes that occur in Alzheimer's Disease are present in people with a history of TBI. The study is recruiting male and female military Veterans or civilians with or without TBI between the ages of 30 and 65.

Institution
MUSC
Recruitment Contact
Laura Lohnes
843-792-7709
lohnes@musc.edu

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