Novel training environment to normalize altered finger force direction post stroke Save

Date Added
June 6th, 2019
PRO Number
Pro00088988
Researcher
Na jin Seo

List of Studies


Profiles_link
Keywords
Exercise, Physical Therapy, Rehabilitation Studies, Stroke Recovery
Summary

The purpose of this study is to determine if 3-dimensional finger force training is an effective tool in restoring hand function post stroke. Persons who survived a stroke 3 to 9 months ago and have a hand impairment will be eligible to participate in this study. Participants will be asked to come to the laboratory to practice controlling the finger force generation 3 times a week for 6 weeks. Participants will see their performance on a computer screen. Participants will also come to the laboratory for additional 4-7 visits for assessments of their upper extremity function. The total duration of the study will be 2.5 months.

Institution
MUSC
Recruitment Contact
Na Jin Seo
8437920084
seon@musc.edu

Remote Delivery of an Exercise Program during Post-Stroke Community Reintegration ? A Pilot Study Save

Date Added
June 4th, 2019
PRO Number
Pro00089218
Researcher
Addie Middleton

List of Studies

Silhouette
Keywords
Exercise, Physical Therapy, Stroke Recovery
Summary

In-person delivery of structured, progressive home exercise programs during the subacute phase of stroke recovery has documented efficacy; however, in-person programs are resource-intensive and not economically sustainable. Advancements in telehealth are opening new avenues for efficient and scalable delivery of services. We will examine "tele" delivery of an important component of post-stroke care, exercise during community reintegration.

Institution
MUSC
Recruitment Contact
Addie Middleton
843-792-0235
middlja@musc.edu

Age-related changes in neuroplasticity impede recovery in post-stroke depression: a novel exercise and brain stimulation paradigm to prime neuroplastic potential Save

Date Added
December 4th, 2018
PRO Number
Pro00083079
Researcher
Ryan Ross

List of Studies

Keywords
Brain, Depression, Exercise, Stroke, Stroke Recovery
Summary

Stroke affects millions of Americans and is a leading cause of disability. In addition to chronic disability, many survivors experience depressive symptoms such as reductions in mood and motivation. Post-stroke depression (PSD) is associated with poorer recovery from stroke, increased health care costs and higher mortality. Additionally, PSD may interfere with the recovery of the nervous system after stroke. Effective treatment options for PSD are limited and often come with side effects, highlighting the need for alternative treatment approaches. Aerobic exercise (AEx) has positive effects on the nervous system, is a powerful anti-depressant, and has limited side effects, yet remains underutilized in stroke survivors with PSD. This study will examine the short-term effects of AEx on the nervous system in stroke survivors with and without PSD. The results will serve as a foundation for the study of AEx as a treatment for PSD.

Institution
MUSC
Recruitment Contact
Ryan Ross
843-792-3477
rossre@musc.edu

Measurement of gait mechanics and movement in the lower extremity amputee Save

Date Added
October 30th, 2018
PRO Number
Pro00082064
Researcher
Aaron Embry

List of Studies

Keywords
Exercise, Movement Disorders, Physical Therapy, Rehabilitation Studies
Summary

Walking after a lower extremity amputation is often difficult. It is important that researchers and clinicians understand the mechanisms that inhibit normal walking function. In this study, we are recruiting individuals with lower extremity limb loss for a walking and balance investigation. We will also be studying matched healthy controls to do similar study procedures. All study procedures will occur on the campus of MUSC by a licensed Physical Therapist and experienced researcher. Any questions should be directed to the coordinator listed.

Institution
MUSC
Recruitment Contact
Aaron Embry
843-792-8198
embry@musc.edu

Promoting Physical Activity via Physical Therapist Following Knee Replacement Save

Date Added
October 5th, 2018
PRO Number
Pro00081254
Researcher
Christine Pellegrini

List of Studies

Keywords
Exercise, Joint, Physical Therapy
Summary

This study aims to examine a physical therapist led physical activity intervention on physical activity levels in knee replacement patients after surgery. The study plans to examine changes in physical activity, physical function, and pain in patients over a 12 week period of time after receiving knee replacement.

Institution
Palmetto
Recruitment Contact
Nicholas Mook
803-777-9236
nmook@email.sc.edu

Post-stroke Optimization of Walking using Explosive Resistance: Concurrent effects on Depression Save

Date Added
August 7th, 2018
PRO Number
Pro00077223
Researcher
Chris Gregory

List of Studies

Silhouette
Keywords
Depression, Exercise, Rehabilitation Studies, Stroke
Summary

Depression contributes directly to disability following a stroke and is the single strongest predictor of quality of life. Treatment of depressive symptoms is associated with better functional recovery and return to activities of daily living. Resistance training can effectively improve post-stroke mobility and has the potential to serve as an alternative (non-drug) anti-depressant treatment option. The purpose of this study is to assess the effects of resistance training on post-stroke depressive symptoms.

Institution
MUSC
Recruitment Contact
Landi Wilson
843-792-9013
wilsolan@musc.edu

Activate For Life: A nurse delivered hybrid telehealth/mHealth aging in place intervention to address pain and fatigue in low-income older adults Save

Date Added
June 5th, 2018
PRO Number
Pro00076835
Researcher
Kathryn Vanravenstein

List of Studies

Silhouette
Keywords
Aging, Chronic Fatigue, Exercise, Pain
Summary

The overall goal of this feasibility study is to test an individualized, nurse-led behavioral health program that leverages home telehealth technology to directly teach low and fixed income older adults residing in the community to reduce their pain and fatigue by improving mobility through strength and balance training in the context of a complementary mental health intervention to address motivation and social support. Specifically, the integrated intervention includes components to address (1) balance and fall prevention (Otago), (2) strengthening and mindfulness (Yoga), and importantly, (3) affective state and social support which are crucial to maintaining motivation (Behavioral Activation). Moreover, these 3 best practices interventions will be enhanced by integrating physical activity data tracking to complement self-report measures, the former of which will be available in real time for patient and provider review, with parameter violations (eg, non-activity during scheduled activity time; overall activity level lower for a set period of time) triggering brief telehealth sessions to address any problems. Finally, participant qualitative feedback will be captured through voice/video recorded diaries focusing on experienced pain, fatigue, sleep, personal reactions to the project and physical activity as well as technology issues they may encounter.

Institution
MUSC
Recruitment Contact
Kathryn VanRavenstein
843-792-3054
vanraven@musc.edu

Incline Training to Personalize Motor Control Interventions after Stroke Save

Date Added
May 3rd, 2018
PRO Number
Pro00077797
Researcher
Mark Bowden

List of Studies

Silhouette
Keywords
Exercise, Physical Therapy, Rehabilitation Studies, Stroke, Stroke Recovery
Summary

Stroke is the leading cause of disability, as many of those affected demonstrate difficulty with movement and
walking. Rehabilitation post-stroke can be challenging and often ineffective because no two stroke survivors
present with the same mobility impairments, yet the same physical therapy interventions are utilized. Thus, a need exists to personalize rehabilitation techniques to improve function and mobility post-stroke. The proposed innovative research will test a framework created to identify the most effective intervention based on a participant's specific motor control problems. We plan to study how self-selected walking speed is impacted by a four-week walking program that incorporates either walking on an inclined or declined treadmill compared to walking on a flat treadmill. We will determine the best intervention for each problem and identify predictors of response. Selecting the correct intervention for personalized motor control problems, as opposed to applying a one-size-fits-all strategy for rehabilitation, is likely to improve walking function in Veterans after stroke.

Institution
MUSC
Recruitment Contact
Brian Cence
(843) 792-2668
cence@musc.edu

Evaluating race specific AGE accumulation as a behavioral biomarker that can reflect optimal health in prostate cancer survivors Save

Date Added
December 19th, 2017
PRO Number
Pro00071004
Researcher
David Turner

List of Studies


Profiles_link
Keywords
Cancer/Other, Exercise, Obesity
Summary

As our bodies use the sugars that we consume for energy they generate waste chemicals known as metabolites. One such group of metabolites is known as advanced glycation end products or AGEs for short. Critically apart from their production as a result of sugar breakdown, AGE levels in the body are also increased by the foods that we eat and when we do not get enough exercise. AGEs may cause many of the side effects experienced by prostate cancer survivors. This study aims to examine the effects of diet change and exercise on AGE levels in prostate cancer survivors.

Institution
MUSC
Recruitment Contact
David Turner
843-876-2309
turnerda@musc.edu

INtervention Study In overweiGHT patients with COPD (INSIGHT COPD) Save

Date Added
March 21st, 2017
PRO Number
Pro00062895
Researcher
Tatsiana Beiko

List of Studies

Silhouette
Keywords
Disease Prevention, Exercise, Lung, Nutrition, Obesity, Pulmonary
Summary

We are conducting the INSIGHT COPD study because symptoms of chronic obstructive pulmonary disease (COPD) and high body mass index (BMI) overlap. There are many medications for patients with COPD, but there is little mention of weight loss as a possible treatment in current research. We are trying to find out if a lifestyle program that promotes modest weight loss and increased physical activity will improve COPD symptoms and lead to better exercise tolerance for those with a high BMI. We are also looking at the effects on shortness of breath, quality-of-life, and cardiovascular disease risk factors. The INSIGHT COPD trial is taking place at many sites across the United States including MUSC, and is planning to enroll approximately 1000 people.

Institution
MUSC
Recruitment Contact
Danielle Woodford
(843) 792-6280
woodfordd@musc.edu

Change_preferences

-- OR --

Create_login