Management of Chronic Pain and PTSD in Veterans with tDCS+Prolonged Exposure Save

Date Added
April 7th, 2020
PRO Number
Pro00098148
Researcher
Bethany Wangelin

List of Studies

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Keywords
Anxiety, Military, Pain
Summary

This research study looks to combine and test a transcranial direct current stimulation (tDCS) for chronic pain and Prolonged Exposure Therapy (PE) for Posttraumatic Stress Disorder (PTSD) in Veterans with chronic pain and PTSD.

Institution
MUSC
Recruitment Contact
Stephanie Hart
843-789-6519
zeigls@musc.edu

Initial Intervention Efficacy, Cortisol, and Oxytocin among Pregnant Women with PTSD Save

Date Added
February 11th, 2020
PRO Number
Pro00096405
Researcher
Mary Shapiro

List of Studies

Keywords
Anxiety, Depression, Pregnancy, Women's Health
Summary

The current study aims to adapt and test a brief computer-assisted intervention for pregnant women with elevated posttraumatic stress symptoms. Twenty pregnant women in their first trimester will be invited to participate in the study if they endorse elevated posttraumatic stress symptoms. Along with self-report measures, hormones will be measured at baseline, one month post-intervention, three months post-intervention, and post-delivery. In addition, women will receive a psychoeducation + skills intervention during their first trimester and women will be offered a "booster session" intervention following delivery to enhance utilization of skills during a critical period for maternal mental and physical health outcomes.

Institution
MUSC
Recruitment Contact
Mary Shapiro
843-792-0259
shapimar@musc.edu

Stressors of Inter-ICU Transfer: Family Centered Care through Telehealth Save

Date Added
December 2nd, 2019
PRO Number
Pro00092555
Researcher
Nandita Nadig

List of Studies

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Keywords
Anxiety, Depression
Summary

The purpose of this research study is to reduce psychological distress and improve communication and family centeredness of care for families of Ventilator Dependent Respiratory Failure (VDRF) patients that have undergone inter-ICU transfer by providing them with timely and adequate information about their transfer of care. This will be accomplished by the development and refinement of our Stressors of Inter-ICU Transfer Telehealth Tool (SITT). The study aims to assess reactions to mocked up SITT domains and support resources of 15-20 family members that have undergone inter-ICU transfer as well as 10 clinicians involved in transfer. The data will drive the refinement of the tool to best meet the needs of the families and clinicians.

Institution
MUSC
Recruitment Contact
Kyle White
8437922297
whiteky@musc.edu

An efficient, exposure-based treatment for PTSD compared to Prolonged Exposure: A non-inferiority randomized trial Save

Date Added
May 7th, 2019
PRO Number
Pro00087882
Researcher
Bethany Wangelin

List of Studies

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Keywords
Anxiety, Depression, Mental Health, Military, Psychiatry, Writing
Summary

PTSD is a prevalent condition for which veterans frequently seek treatment in the VA healthcare system. There are a number of first-line PTSD treatment approaches available, such as Prolonged Exposure and Cognitive Processing Therapy. However, the efficacy rates of these treatments is not as high as what has been observed with civilian populations and approximately 36% of individuals drop out of these treatments prematurely. A proposed alternative to these treatments is Written Exposure Therapy (WET), a brief, 5 session intervention that has been shown to reduce symptoms of PTSD and contribute to lower dropout rates. The goal of this study is to investigate whether WET is as effective compared to Prolonged Exposure (PE) in the treatment of PTSD in a sample of veterans diagnosed with PTSD. It will involve approximately 150 Veterans. This research is funded by the Department of Veterans Affairs.

Institution
MUSC
Recruitment Contact
Stephanie Hart
843-789-6519
zeigls@musc.edu

Accelerated Repetitive TMS for Affective Dysfunction: Establishing the Dose-Response Curve Save

Date Added
January 4th, 2019
PRO Number
Pro00084111
Researcher
Lisa Mcteague

List of Studies


Profiles_link
Keywords
Anxiety, Depression
Summary

The goal of this work is to identify the most efficacious range of doses for a short-term (i.e., 1 week) course of high-dose brain stimulation for major depression.

Institution
MUSC
Recruitment Contact
Lisa McTeague
843-792-8274
mcteague@musc.edu

Neurobiological Correlates of Fear in Veterans with Military Sexual Trauma Save

Date Added
December 4th, 2018
PRO Number
Pro00083967
Researcher
Bethany Wangelin

List of Studies

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Keywords
Anxiety, Genetics, Mental Health, Military, Psychiatry
Summary

The purpose of this study is to better understand the different ways that female Veterans are affected by their experience with military sexual trauma (MST) and to look at the role of several factors that cause some people, but not others, to develop posttraumatic stress disorder (PTSD) or PTSD symptoms. This study is being conducted at the Charleston VA Medical Center, Tuscaloosa VA Medical Center and Atlanta VA Healthcare System. It will involve approximately 150 female Veterans who have experienced MST.

Institution
MUSC
Recruitment Contact
Stephanie Hart
843-789-6519
zeigls@musc.edu

Coping Behavior: Laboratory Assessment and Clinical Correlates Save

Date Added
December 4th, 2018
PRO Number
Pro00081364
Researcher
Christopher Sege

List of Studies

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Keywords
Anxiety, Depression, Healthy Volunteer Studies
Summary

This is a laboratory study of the brain and bodily bases of emotional coping. The study examines how the brain and body respond in different coping environments, as well as how mental health concerns (anxiety, depression, etc.) affect responses in those environments. Participants wear sensors on their hands, arms, and head while performing a task where they control emotional images in different ways. In addition, participants answer a number of questions about mental health concerns they might have. Because anxiety, depression and related problems can fundamentally alter coping, this study could inform how such problems are identified and treated.

Institution
MUSC
Recruitment Contact
Christopher Sege
8437928465
sege@musc.edu

The Psychological Impact of Inter-ICU Transfers Save

Date Added
November 6th, 2018
PRO Number
Pro00080530
Researcher
Nandita Nadig

List of Studies

Silhouette
Keywords
Anxiety, Depression
Summary

The purpose of this research study is to determine the psychological burden placed on the families of patients in the intensive care unit (ICU) who have ventilator-dependent respiratory failure, VDRF, as compared to the burden placed on the families of patients with VDRF who have been transferred from one ICU to another. This study aims to determine if inter-ICU transfer, compared to those who are not transferred, leave patients and families with more symptoms such as of depression, anxiety, and stress. Family members of patients admitted to the ICU will be asked to complete a survey that will last between 20 and 30 minutes. The surveys will be used to evaluate the difference in psychological distress placed on families whose loved ones are directly admitted to the ICU as compared to being transferred from one ICU to another.

Institution
MUSC
Recruitment Contact
Kyle White
(843) 792-8233
whiteky@musc.edu

Developing a Novel rTMS Intervention for Transdiagnostic Psychosocial Rehabilitation: A Dose-finding Study Save

Date Added
October 2nd, 2018
PRO Number
Pro00082315
Researcher
Lisa Mcteague

List of Studies


Profiles_link
Keywords
Anxiety, Depression
Summary

The goal of this work is to identify the most efficacious dose for a high-dose, short-term brain stimulation intervention for anxiety and depression in veterans.

Institution
MUSC
Recruitment Contact
Lisa McTeague
8437928274
mcteague@musc.edu

Odor Disturbances: Clinical Care Registry Save

Date Added
September 26th, 2018
PRO Number
Pro00080333
Researcher
Thomas Uhde

List of Studies


Profiles_link
Keywords
ADD/ADHD, Adolescents, Aging, Allergy, Alzheimers, Anxiety, Asthma, Autism, Autoimmune disease, Central Nervous System, Chronic Fatigue, Depression, Environmental Factors, Fibromyalgia, Inflammation, Memory Loss, Nervous System, Parkinsons, Psychiatry
Summary

Candidates for this study may or may not report disturbances in odor perception as their primary reason for seeking treatment at MUSC. This study is designed to collect long term, observational data from patients who are being treated with routine clinical care in health clinics at MUSC. Data from clinical questionnaires will be de-identified and stored in a database.

Institution
MUSC
Recruitment Contact
Richard Simmons
843-792-7439
simmr@musc.edu

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