An efficient, exposure-based treatment for PTSD compared to Prolonged Exposure: A non-inferiority randomized trial Save

Date Added
May 7th, 2019
PRO Number
Pro00087882
Researcher
Ronald Acierno

List of Studies


Profiles_link
Keywords
Anxiety, Depression, Mental Health, Military, Psychiatry, Writing
Summary

PTSD is a prevalent condition for which veterans frequently seek treatment in the VA healthcare system. There are a number of first-line PTSD treatment approaches available, such as Prolonged Exposure and Cognitive Processing Therapy. However, the efficacy rates of these treatments is not as high as what has been observed with civilian populations and approximately 36% of individuals drop out of these treatments prematurely. A proposed alternative to these treatments is Written Exposure Therapy (WET), a brief, 5 session intervention that has been shown to reduce symptoms of PTSD and contribute to lower dropout rates. The goal of this study is to investigate whether WET is as effective compared to Prolonged Exposure (PE) in the treatment of PTSD in a sample of veterans diagnosed with PTSD. It will involve approximately 150 Veterans. This research is funded by the Department of Veterans Affairs.

Institution
MUSC
Recruitment Contact
Stephanie Hart
843-789-6519
zeigls@musc.edu

The Effect of In-bed Electronic Social Media Use on Sleep and Mood in an Adolescent Population: A Survey-Based Study Save

Date Added
February 8th, 2019
PRO Number
Pro00080994
Researcher
Jesse Pearce

List of Studies

Keywords
Adolescents, Anxiety, Depression
Summary

This survey based research project will investigate the link between bedtime electronic media use in adolescents and symptoms of depression, anxiety, and stress.Subjects will be South Carolina adolescents aged 13-18. Surveys will be administered online and at the AnMed Children's Health Center.

Institution
MUSC
Recruitment Contact
Jesse Pearce
8642804790
pearceje@musc.edu

THE EFFECTS OF A GRADUATE PHYSICIAN ASSISTANT PROGRAM ON ATTITUDES TOWARD STRESS, PERCEPTION OF FINANCIAL STRAIN, AND EMPATHY TOWARD PATIENTS Save

Date Added
January 17th, 2019
PRO Number
Pro00082670
Researcher
Helen Martin

List of Studies

Silhouette
Keywords
Anxiety, Depression, Stress Disorders
Summary

Participants will be required to complete one set of online survey instruments, consisting of four unique surveys, at eight critical points throughout their graduate program. Early in the study, participants will also be asked to complete a one-time Participant Demographics form. The four surveys include the Brief Symptom inventory 18(BSI 18), the Financial Anxiety Scale, a multidimensional scale of perceived stress, as well as the Jefferson Empathy Scale. The financial anxiety scale and the perceived stress scale will each take less than five minutes to complete. Both the financial anxiety scale and the perceived stress scale will be administered through CMU's REDCap system (Research Electronic Data Capture) managed by the IT division of Central Michigan University. The BSI 18 will take approximately 3 to 5 minutes to complete and will be administered through the manufacturer called Pearson using Q-global. The final survey is the Jefferson empathy scale that will be administered through a link generated by Jefferson Medical School. Participants will receive a separate electronic email invitation from Q-global to complete the BSI18. Administration of the four online surveys will take place at the endpoint of the first semester and at the midpoint of each consecutive semester until the sixth semester, along with two additional administrations at the end of semesters four and six.

Institution
MUSC
Recruitment Contact
Helen Martin
843 792 0404
marthele@musc.edu

Accelerated Repetitive TMS for Affective Dysfunction: Establishing the Dose-Response Curve Save

Date Added
January 4th, 2019
PRO Number
Pro00084111
Researcher
Lisa Mcteague

List of Studies


Profiles_link
Keywords
Anxiety, Depression
Summary

The goal of this work is to identify the most efficacious range of doses for a short-term (i.e., 1 week) course of high-dose brain stimulation for major depression.

Institution
MUSC
Recruitment Contact
Lisa McTeague
843-792-8274
mcteague@musc.edu

Neurobiological Correlates of Fear in Veterans with Military Sexual Trauma Save

Date Added
December 4th, 2018
PRO Number
Pro00083967
Researcher
Ronald Acierno

List of Studies


Profiles_link
Keywords
Anxiety, Genetics, Mental Health, Military, Psychiatry
Summary

The purpose of this study is to better understand the different ways that female Veterans are affected by their experience with military sexual trauma (MST) and to look at the role of several factors that cause some people, but not others, to develop posttraumatic stress disorder (PTSD) or PTSD symptoms. This study is being conducted at the Charleston VA Medical Center, Tuscaloosa VA Medical Center and Atlanta VA Healthcare System. It will involve approximately 150 female Veterans who have experienced MST.

Institution
MUSC
Recruitment Contact
Stephanie Hart
843-789-6519
zeigls@musc.edu

The Psychological Impact of Inter-ICU Transfers Save

Date Added
November 6th, 2018
PRO Number
Pro00080530
Researcher
Nandita Nadig

List of Studies

Silhouette
Keywords
Anxiety, Depression
Summary

The purpose of this research study is to determine the psychological burden placed on the families of patients in the intensive care unit (ICU) who have ventilator-dependent respiratory failure, VDRF, as compared to the burden placed on the families of patients with VDRF who have been transferred from one ICU to another. This study aims to determine if inter-ICU transfer, compared to those who are not transferred, leave patients and families with more symptoms such as of depression, anxiety, and stress. Family members of patients admitted to the ICU will be asked to complete a survey that will last between 20 and 30 minutes. The surveys will be used to evaluate the difference in psychological distress placed on families whose loved ones are directly admitted to the ICU as compared to being transferred from one ICU to another.

Institution
MUSC
Recruitment Contact
Katherine Wallace
(843) 792-4557
wallacka@musc.edu

Developing a Novel rTMS Intervention for Transdiagnostic Psychosocial Rehabilitation: A Dose-finding Study Save

Date Added
October 2nd, 2018
PRO Number
Pro00082315
Researcher
Lisa Mcteague

List of Studies


Profiles_link
Keywords
Anxiety, Depression
Summary

The goal of this work is to identify the most efficacious dose for a high-dose, short-term brain stimulation intervention for anxiety and depression in veterans.

Institution
MUSC
Recruitment Contact
Lisa McTeague
8437928274
mcteague@musc.edu

Odor Disturbances: Clinical Care Registry Save

Date Added
September 26th, 2018
PRO Number
Pro00080333
Researcher
Thomas Uhde

List of Studies


Profiles_link
Keywords
ADD/ADHD, Adolescents, Aging, Allergy, Alzheimers, Anxiety, Asthma, Autism, Autoimmune disease, Central Nervous System, Chronic Fatigue, Depression, Environmental Factors, Fibromyalgia, Inflammation, Memory Loss, Nervous System, Parkinsons, Psychiatry
Summary

Candidates for this study may or may not report disturbances in odor perception as their primary reason for seeking treatment at MUSC. This study is designed to collect long term, observational data from patients who are being treated with routine clinical care in health clinics at MUSC. Data from clinical questionnaires will be de-identified and stored in a database.

Institution
MUSC
Recruitment Contact
Richard Simmons
843-792-7439
simmr@musc.edu

Improving Function Through Primary Care Treatment of PTSD Save

Date Added
July 3rd, 2018
PRO Number
Pro00078946
Researcher
Ronald Acierno

List of Studies


Profiles_link
Keywords
Anxiety, Depression, Mental Health, Military, Psychiatry
Summary

This research is taking place at the Ralph H. Johnson VAMC and surrounding Community-Based Outpatient Clinics (CBOCs). This study is examining the effectiveness of PE-PC in VHA primary care mental health integration (PCMHI) clinics. We will randomize Veterans presenting in VA PC with chronic PTSD who meet minimal inclusion/exclusion criteria to receive PE-PC (four, 30-minute weekly sessions) or PCMHI treatment as usual.

Institution
MUSC
Recruitment Contact
Stephanie Hart
843-789-6519
zeigls@musc.edu

Peer Social Support During In Vivo Exposure for PTSD: A Program to Address Dropout from Prolonged Exposure Save

Date Added
April 3rd, 2018
PRO Number
Pro00075914
Researcher
Wendy Muzzy

List of Studies


Profiles_link
Keywords
Anxiety, Depression, Mental Health, Military, Psychiatry
Summary

Veterans who have prematurely dropped out of exposure therapy for PTSD will be contacted and offered the opportunity to return to treatment, this time with the assistance of a Veteran who has successfully completed this treatment in the past. Participants may receive a PE "Workout Buddy." This peer will meet them at the in vivo exposure therapy location and offer support and encouragement while the patient remains in that location. Participants may receive a PE general support peer. This peer will contact them once per week to check in about treatment progress and encourage session attendance, as well as discuss any life stresses. As the PTSD treatment standards in Charleston and other VA sites across the country increasingly include telemedicine delivered care, both in person and telemedicine based exposure therapy recipients will be included.

Institution
MUSC
Recruitment Contact
Stephanie Hart
843-789-6519
zeigls@musc.edu

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