Extinguishing Fear and Craving: Neuromodulating Shared Circuits Save

Date Added
March 7th, 2017
PRO Number
Pro00064233
Researcher
Lisa Mcteague

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Keywords
Alcohol, Anxiety, Brain, Depression
Summary

Individuals with anxiety disorders are approximately twice as likely as the general population to experience alcohol addiction and vice versa. The affinity toward addiction is especially high in the case of posttraumatic stress disorder (PTSD). Animal and human work has suggested that the neurocircuitry largely overlaps in both the expression and extinction of fear and craving. This study involves utilizing one session of non-invasive brain stimulation (repetitive transcranial magnetic stimulation) to enhance extinction learning as measured with functional magnetic resonance imaging, in both healthy individuals and those with PTSD and alcohol addiction. While this is a single session study, the goal of this study is two identify promising new brain targets to be used therapeutically for individuals suffering from PTSD and alcohol addiction.

Institution
MUSC
Recruitment Contact
Lisa McTeague
843-792-8274
mcteague@musc.edu

Neuromodulation of Cognitive Control Save

Date Added
April 5th, 2016
PRO Number
Pro00053644
Researcher
Lisa Mcteague

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Keywords
Healthy Volunteer Studies
Summary

In this study we are assessing ways in which people pay attention and make decisions. We will test whether certain brain regions are central to these processes by using brain stimulation, specifically transcranial magnetic stimulation to briefly disrupt attention and decisions in the context of a computer game.

Institution
MUSC
Recruitment Contact
Lisa McTeague
843-792-8274
mcteague@musc.edu

Remediating Emotion Deficits in PTSD: Probing and Modulating Neurocircuits Save

Date Added
November 4th, 2014
PRO Number
Pro00038957
Researcher
Lisa Mcteague

Silhouette
Keywords
Anxiety, Brain, Depression
Summary

The current investigation uses a brain-based technique, transcranial magnetic stimulation (TMS), which has helped to treat depression, to try to stimulate those brain regions understood to be essential to emotional experience and impaired in PTSD. In summary, the aim is to enhance emotion engagement and regulation and possibly uncover new brain-based interventions that could help ready the brain so an individual with PTSD could then fully engage and thus optimize emotion-focused psychotherapy.

Institution
MUSC
Recruitment Contact
Lisa McTeague
(843) 792-8274
mcteague@musc.edu

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