Neuromodulation of Cognitive Control Neurocircuits for Stroke Rehabilitation Save

Date Added
May 7th, 2019
PRO Number
Pro00086015
Researcher
Lisa Mcteague

List of Studies


Profiles_link
Keywords
Memory Loss, Stroke, Stroke Recovery
Summary

The goal of this study is to determine the pattern of cognitive impairment in chronic stroke, both in terms of performance during cognitive testing as well as brain neurocircuit activation.

Institution
MUSC
Recruitment Contact
Lisa McTeague
843-792-8274
mcteague@musc.edu

Accelerated Repetitive TMS for Affective Dysfunction: Establishing the Dose-Response Curve Save

Date Added
January 4th, 2019
PRO Number
Pro00084111
Researcher
Lisa Mcteague

List of Studies


Profiles_link
Keywords
Anxiety, Depression
Summary

The goal of this work is to identify the most efficacious range of doses for a short-term (i.e., 1 week) course of high-dose brain stimulation for major depression.

Institution
MUSC
Recruitment Contact
Lisa McTeague
843-792-8274
mcteague@musc.edu

Neuromodulation and Plasticity in Cognitive Control Neurocircuitry in Chronic Stroke Save

Date Added
November 6th, 2018
PRO Number
Pro00083136
Researcher
Lisa Mcteague

List of Studies


Profiles_link
Keywords
Stroke, Stroke Recovery
Summary

The goal of this pilot study is to determine whether a repetitive high-dose form of non-invasive brain stimulation is a promising and safe treatment for stroke-related cognitive difficulties. Repetitive transcranial magnetic stimulation (rTMS) is an FDA approved treatment for depression, and is used commonly to treat people for their depression. In studies of rTMS for depression and other disorders, individuals have experienced improved cognitive function. Thus, we are testing here whether cognitive function in individuals with chronic stroke could be improved by rTMS.

Institution
MUSC
Recruitment Contact
Lisa McTeague
843-792-8274
mcteague@musc.edu

Developing a Novel rTMS Intervention for Transdiagnostic Psychosocial Rehabilitation: A Dose-finding Study Save

Date Added
October 2nd, 2018
PRO Number
Pro00082315
Researcher
Lisa Mcteague

List of Studies


Profiles_link
Keywords
Anxiety, Depression
Summary

The goal of this work is to identify the most efficacious dose for a high-dose, short-term brain stimulation intervention for anxiety and depression in veterans.

Institution
MUSC
Recruitment Contact
Lisa McTeague
8437928274
mcteague@musc.edu

The Effects of Theta-Burst Stimulation Duration on Human Motor Cortex Excitability Save

Date Added
August 1st, 2017
PRO Number
Pro00068775
Researcher
Lisa Mcteague

List of Studies


Profiles_link
Keywords
Psychiatry, Rehabilitation Studies
Summary

The study will use a new method for non-invasively examining the brain called Transcranial Magnetic Stimulation (TMS). TMS involves placing a coil of wire above the scalp and intermittently passing a very powerful current through it. This current produces energy in the form of a magnetic field that passes through the scalp. The magnetic field, in turn, induces a much weaker electrical current in the brain, causing the neurons directly under the coil to activate for a brief period of time. The U.S. Federal Drug Administration has approved TMS as a method for treating depression since 2008. By using TMS, we can evaluate how well your brain is controlling one of your hand or leg muscles. One way to measure this is by recording activity via electrodes on the hand opposite the side of the brain being stimulated. For example we will be stimulating on the left side of the brain and recording from electrodes on your right hand. In this study we are determining the effects of different types of repetitive Transcranial Magnetic Stimulation (rTMS) protocols on hand movement. rTMS means that the magnetic pulses are applied consecutively, and at a specified pace- the frequency. The specific type of rTMS you will receive is called "theta-burst stimulation" (TBS). TBS is characterized by a specific frequency of stimulation.

Institution
MUSC
Recruitment Contact
John Henderson
792-5560
henderjs@musc.edu

Remediating Emotion Deficits in PTSD: Probing and Modulating Neurocircuits Save

Date Added
November 4th, 2014
PRO Number
Pro00038957
Researcher
Lisa Mcteague

List of Studies


Profiles_link
Keywords
Anxiety, Brain, Depression
Summary

The current investigation uses a brain-based technique, transcranial magnetic stimulation (TMS), which has helped to treat depression, to try to stimulate those brain regions understood to be essential to emotional experience and impaired in PTSD. In summary, the aim is to enhance emotion engagement and regulation and possibly uncover new brain-based interventions that could help ready the brain so an individual with PTSD could then fully engage and thus optimize emotion-focused psychotherapy.

Institution
MUSC
Recruitment Contact
Lisa McTeague
(843) 792-8274
mcteague@musc.edu

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