The goal of this study is to better understand peri-operative outcomes in patients with obstructive sleep apnea (OSA) undergoing sinonasal surgery. Specifically, this study will examine oxygen saturation levels and need for supplemental oxygen during the first night following surgery. The tolerance of continuous positive airway pressure (CPAP) therapy in the weeks following surgery will also be assessed.

The Sleep Research Data Repository (SRDR) aimed to systematically collect, analyze and store for future research sleep and sleep disorders related biological and psychological information. It will include sleep physiological measurements and the results of interviews, questionnaires, and laboratory tests. The SRDR will contain sleep related information obtained from healthy subjects and patients with psychiatric, substance abuse, neurological disorders, or any medical conditions associated with sleep disturbances. SRDR data will be made available to current and future IRB-approved investigators associated with this protocol.

This study will attempt to use a type of non-invasive brain stimulation technology during sleep to improve measures of sleep quality and memory in young healthy students and older adults. The type of brain stimulation is called transcranial direct current stimulation (tDCS), which uses small currents of electricity to increase or decrease the activity of specific areas of the brain.

The mechanism of how poor sleep affects pain is poorly-understood. The purpose of this human laboratory study is to examine the effects of sleep disruption on laboratory-measured pain thresholds, pain reports, and stress response reactivity. Four healthy men and women will undergo one night of sleep disruption. Pain and stress reactivity will be measured before and after sleep disruption in an effort to understand the mechanism of how poor sleep affects the pain experience. The information gathered from this pilot study will inform a larger study evaluating gender differences in response to sleep deprivation, and ultimately in a therapeutic trial of a sleep medication in fibromyalgia.

The goal of this study is to document the phenomenology and longitudinal course of illness in patients with sleep panic disorder, narcolepsy (associated with fear-induced cataplexy), sleep paralysis, PTSD, nightmare disorder (not associated with PTSD), and sleep seizures disorders. Subjects will complete questionnaires, complete semi-structured interview, and be guided to complete a timeline of life events and illness episodes, etc. A second visit will ensure completion of timeline information and allow clinicians to have information to plot on a life chart to view the longitudinal course of illness.