South Carolina Research Studies Directory

A Randomized, Double-blind, Multicenter, Placebo-controlled Study of Adjunctive Aticaprant Plus an Antidepressant for Relapse Prevention in Major Depressive Disorder (MDD) With Moderate-to-severe Anhedonia

Date Added
September 18th, 2024
PRO Number
Pro00138636
Researcher
Thomas Uhde

List of Studies


Keywords
Depression, Mental Health
Summary

This study will assess an adjunctive treatment for major depressive disorder (MDD) called Aticaprant. Adults with MDD that are currently on an antidepressant but continue to experience prominent anhedonia may qualify.

Institution
MUSC
Recruitment Contact
Matthew Woodson
8437925428
woodsonm@musc.edu

A Two-Part Multicenter, Double-Blind, Randomized Placebo-Controlled Study to Evaluate Efficacy and Safety and the Maintenance of Effect of 20-mg Seltorexant as Adjunctive Therapy to Antidepressants in Adult and Elderly Patients with Major Depressive Disorder with Insomnia Symptoms

Date Added
August 9th, 2024
PRO Number
Pro00138340
Researcher
Thomas Uhde

List of Studies


Keywords
Depression, Sleep Disorders
Summary

This Study will assess whether 20 mg of seltorexant compared with placebo as adjunctive therapy to an SSRI/SNRI antidepressant improves depressive symptoms in participants with MDD and insomnia who have had an inadequate response to current SSRI/SNRI antidepressant therapy.

Institution
MUSC
Recruitment Contact
Matthew Woodson
8437925428
woodsonm@musc.edu



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