The Psychological Impact of Inter-ICU Transfers Save

Date Added
November 6th, 2018
PRO Number
Pro00080530
Researcher
Nandita Nadig
Keywords
Anxiety, Depression
Summary

The purpose of this research study is to determine the psychological burden placed on the families of patients in the intensive care unit (ICU) who have ventilator-dependent respiratory failure, VDRF, as compared to the burden placed on the families of patients with VDRF who have been transferred from one ICU to another. This study aims to determine if inter-ICU transfer, compared to those who are not transferred, leave patients and families with more symptoms such as of depression, anxiety, and stress. Family members of patients admitted to the ICU will be asked to complete a survey that will last between 20 and 30 minutes. The surveys will be used to evaluate the difference in psychological distress placed on families whose loved ones are directly admitted to the ICU as compared to being transferred from one ICU to another.

Institution
MUSC
Recruitment Contact
Katherine Wallace
(843) 792-4557
wallacka@musc.edu

Developing a Novel rTMS Intervention for Transdiagnostic Psychosocial Rehabilitation: A Dose-finding Study Save

Date Added
October 2nd, 2018
PRO Number
Pro00082315
Researcher
Lisa Mcteague
Keywords
Anxiety, Depression
Summary

The goal of this work is to identify the most efficacious dose for a high-dose, short-term brain stimulation intervention for anxiety and depression in veterans.

Institution
MUSC
Recruitment Contact
Lisa McTeague
8437928274
mcteague@musc.edu

A STEPPED-CARE TELEHEALTH APPROACH TO TREAT DISTRESS IN RURAL CANCER SURVIVORS Save

Date Added
October 2nd, 2018
PRO Number
Pro00082222
Researcher
Chanita Hughes-halbert
Keywords
Cancer, Depression
Summary

This study is for men and women with a history of cancer and distress (i.e. anxiety and/or depressive symptoms). The purpose of this research study is to determine the feasibility and effects of a telephone-based, stepped-care mental health intervention (which means that the level of intervention is based on the severity of symptoms) versus enhanced usual care for post-treatment cancer survivors with moderate or severe levels of emotional distress (anxiety and/or depressive symptoms).

Institution
MUSC
Recruitment Contact
Nancy McGaha
864-725-7129
nmcgaha@selfregional.org

Odor Disturbances: Clinical Care Registry Save

Date Added
September 26th, 2018
PRO Number
Pro00080333
Researcher
Thomas Uhde
Keywords
ADD/ADHD, Adolescents, Aging, Allergy, Alzheimers, Anxiety, Asthma, Autism, Autoimmune disease, Central Nervous System, Chronic Fatigue, Depression, Environmental Factors, Fibromyalgia, Inflammation, Memory Loss, Nervous System, Parkinsons, Psychiatry
Summary

Candidates for this study may or may not report disturbances in odor perception as their primary reason for seeking treatment at MUSC. This study is designed to collect long term, observational data from patients who are being treated with routine clinical care in health clinics at MUSC. Data from clinical questionnaires will be de-identified and stored in a database.

Institution
MUSC
Recruitment Contact
Richard Simmons
843-792-7439
simmr@musc.edu

Post-stroke Optimization of Walking using Explosive Resistance: Concurrent effects on Depression Save

Date Added
August 7th, 2018
PRO Number
Pro00077223
Researcher
Chris Gregory
Keywords
Depression, Exercise, Rehabilitation Studies, Stroke
Summary

Depression contributes directly to disability following a stroke and is the single strongest predictor of quality of life. Treatment of depressive symptoms is associated with better functional recovery and return to activities of daily living. Resistance training can effectively improve post-stroke mobility and has the potential to serve as an alternative (non-drug) anti-depressant treatment option. The purpose of this study is to assess the effects of resistance training on post-stroke depressive symptoms.

Institution
MUSC
Recruitment Contact
Landi Wilson
843-792-9013
wilsolan@musc.edu

Improving Function Through Primary Care Treatment of PTSD Save

Date Added
July 3rd, 2018
PRO Number
Pro00078946
Researcher
Ronald Acierno
Keywords
Anxiety, Depression, Mental Health, Military, Psychiatry
Summary

This research is taking place at the Ralph H. Johnson VAMC and surrounding Community-Based Outpatient Clinics (CBOCs). This study is examining the effectiveness of PE-PC in VHA primary care mental health integration (PCMHI) clinics. We will randomize Veterans presenting in VA PC with chronic PTSD who meet minimal inclusion/exclusion criteria to receive PE-PC (four, 30-minute weekly sessions) or PCMHI treatment as usual.

Institution
MUSC
Recruitment Contact
Stephanie Zeigler
843-789-6519
zeigls@musc.edu

Peer Social Support During In Vivo Exposure for PTSD: A Program to Address Dropout from Prolonged Exposure Save

Date Added
April 3rd, 2018
PRO Number
Pro00075914
Researcher
Ronald Acierno
Keywords
Anxiety, Depression, Mental Health, Military, Psychiatry
Summary

Veterans who have prematurely dropped out of exposure therapy for PTSD will be contacted and offered the opportunity to return to treatment, this time with the assistance of a Veteran who has successfully completed this treatment in the past. Participants may receive a PE "Workout Buddy." This peer will meet them at the in vivo exposure therapy location and offer support an encouragement while the patient remains in that location. Participants may receive a PE general support peer. This peer will contact them once per week to check in about treatment progress and encourage session attendance, as well as discuss any life stresses. As the PTSD treatment standards in Charleston and other VA sites across the country increasingly include telemedicine delivered care, both in person and telemedicine based exposure therapy recipients will be included.

Institution
MUSC
Recruitment Contact
Stephanie Zeigler
843-789-6519
zeigls@musc.edu

Randomized controlled trial of EEG/fMRI Controlled TMS For Treating Depression Save

Date Added
February 6th, 2018
PRO Number
Pro00074695
Researcher
Mark George
Keywords
Depression
Summary

Currently rTMS for treating depression is delivered without knowing whether the TMS pulses are synchronized with the patient's brain rhythms. We have built a combined TMS/fMRI/EEG machine and have shown that delivering a TMS pulse over the prefrontal cortex precisely timed produces a bigger brain response. We now wonder if precisely timing the TMS pulses might enhance the antidepressant effects of TMS. We will randomize depressed patients to either the current standard of care, or the same TMS but precisely timed.

Institution
MUSC
Recruitment Contact
Morgan Dancy
843 876 5142
maddoxm@musc.edu

An Open Label Study to Assess the Feasibility and Tolerability of Accelerated Theta Burst Repetitive Transcranial Magnetic Stimulation (iTBS-rTMS) for the Treatment of Post-Partum Depression Save

Date Added
January 2nd, 2018
PRO Number
Pro00073886
Researcher
Constance Guille
Keywords
Depression, Post Partum Depression
Summary

This is an open-label study designed to investigate the feasibility and tolerability of a novel TMS treatment protocol to treat depression in women with post-partum depression. It is known that TMS can effectively treat depression. The FDA approved protocol lasts 6 weeks and is not feasible for many women with post-partum depression. We are investigating a 3 day treatment for depression which may be more acceptable for this population. We further hope to characterize the ant-depressant effect of this protocol in order to design a larger trial.

Institution
MUSC
Recruitment Contact
James Fox
843-792-2123 pgr 14687
foxj@musc.edu

Randomized Controlled Trial of AboutFace: A Novel Video Storytelling Resource to Improve Access, Engagement, and Utilization of Mental Health Treatment among Veterans with PTSD Save

Date Added
December 5th, 2017
PRO Number
Pro00072331
Researcher
Anouk Grubaugh
Keywords
Anxiety, Depression, Military, Psychiatry, Stress Disorders
Summary

Behavioral health problems among Veterans have raised awareness of the critical need for more reliable, effective, and accessible ways to recognize those in need, direct them to help, and ensure that they receive the best evidence-based care available. AboutFace is a novel peer education program that features the personal stories of Veterans and is designed to improve Veterans' likelihood of engaging in PTSD specialty care. Using a randomized controlled study design we propose to compare the efficacy of AboutFace relative to standard care for improving treatment engagement and outcomes. Additional data from VA providers will provide valuable information on wide scale implementation and dissemination of AboutFace. If AboutFace increases access of services, data will have broad implications for overcoming barriers to care for Veterans with PTSD and other stigmatized conditions.

Institution
MUSC
Recruitment Contact
Anouk Grubaugh
843-532-6672
grubaugh@musc.edu

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