PTSD is a prevalent condition for which veterans frequently seek treatment in the VA healthcare system. There are a number of first-line PTSD treatment approaches available, such as Prolonged Exposure and Cognitive Processing Therapy. However, the efficacy rates of these treatments is not as high as what has been observed with civilian populations and approximately 36% of individuals drop out of these treatments prematurely. A proposed alternative to these treatments is Written Exposure Therapy (WET), a brief, 5 session intervention that has been shown to reduce symptoms of PTSD and contribute to lower dropout rates. The goal of this study is to investigate whether WET is as effective compared to Prolonged Exposure (PE) in the treatment of PTSD in a sample of veterans diagnosed with PTSD. It will involve approximately 150 Veterans. This research is funded by the Department of Veterans Affairs.
This survey based research project will investigate the link between bedtime electronic media use in adolescents and symptoms of depression, anxiety, and stress.Subjects will be South Carolina adolescents aged 13-18. Surveys will be administered online and at the AnMed Children's Health Center.
The purpose of this study is to determine if taking JNJ-67953964 (the investigational medication), in addition to a currently prescribed anti-depressant, is useful and safe for treating patients with Major Depressive Disorder. This will be compared to placebo plus subjects' current anti-depressant medication.
Participants will be required to complete one set of online survey instruments, consisting of four unique surveys, at eight critical points throughout their graduate program. Early in the study, participants will also be asked to complete a one-time Participant Demographics form. The four surveys include the Brief Symptom inventory 18(BSI 18), the Financial Anxiety Scale, a multidimensional scale of perceived stress, as well as the Jefferson Empathy Scale. The financial anxiety scale and the perceived stress scale will each take less than five minutes to complete. Both the financial anxiety scale and the perceived stress scale will be administered through CMU's REDCap system (Research Electronic Data Capture) managed by the IT division of Central Michigan University. The BSI 18 will take approximately 3 to 5 minutes to complete and will be administered through the manufacturer called Pearson using Q-global. The final survey is the Jefferson empathy scale that will be administered through a link generated by Jefferson Medical School. Participants will receive a separate electronic email invitation from Q-global to complete the BSI18. Administration of the four online surveys will take place at the endpoint of the first semester and at the midpoint of each consecutive semester until the sixth semester, along with two additional administrations at the end of semesters four and six.
Stroke affects millions of Americans and is a leading cause of disability. In addition to chronic disability, many survivors experience depressive symptoms such as reductions in mood and motivation. Post-stroke depression (PSD) is associated with poorer recovery from stroke, increased health care costs and higher mortality. Additionally, PSD may interfere with the recovery of the nervous system after stroke. Effective treatment options for PSD are limited and often come with side effects, highlighting the need for alternative treatment approaches. Aerobic exercise (AEx) has positive effects on the nervous system, is a powerful anti-depressant, and has limited side effects, yet remains underutilized in stroke survivors with PSD. This study will examine the short-term effects of AEx on the nervous system in stroke survivors with and without PSD. The results will serve as a foundation for the study of AEx as a treatment for PSD.
The purpose of this research study is to determine the psychological burden placed on the families of patients in the intensive care unit (ICU) who have ventilator-dependent respiratory failure, VDRF, as compared to the burden placed on the families of patients with VDRF who have been transferred from one ICU to another. This study aims to determine if inter-ICU transfer, compared to those who are not transferred, leave patients and families with more symptoms such as of depression, anxiety, and stress. Family members of patients admitted to the ICU will be asked to complete a survey that will last between 20 and 30 minutes. The surveys will be used to evaluate the difference in psychological distress placed on families whose loved ones are directly admitted to the ICU as compared to being transferred from one ICU to another.
This study is for men and women with a history of cancer and distress (i.e. anxiety and/or depressive symptoms). The purpose of this research study is to determine the feasibility and effects of a telephone-based, stepped-care mental health intervention (which means that the level of intervention is based on the severity of symptoms) versus enhanced usual care for post-treatment cancer survivors with moderate or severe levels of emotional distress (anxiety and/or depressive symptoms).
Candidates for this study may or may not report disturbances in odor perception as their primary reason for seeking treatment at MUSC. This study is designed to collect long term, observational data from patients who are being treated with routine clinical care in health clinics at MUSC. Data from clinical questionnaires will be de-identified and stored in a database.