ATHN 9 is a natural history study to assess the safety of various Von Willebrand Factor (VWF) regimens for different indications (on-demand, surgery and prophylaxis) in adult and pediatric participants with clinically severe congenital VWD.
Periodontitis is a major cause of irreversible destruction of tissues leading to a loss of attachment between teeth and their supporting tissues. Several strategies are being tested experimentally to enhance periodontal regeneration, one of them being the use of stem cells.
In this study, eligible participants that are patients of the James B. Edwards College of Dental Medicine scheduled to have their teeth extracted. The teeth being extracted from patients during oral surgery, which otherwise would be discarded, will be donated for laboratory tests.