ATHN 9 is a natural history study to assess the safety of various Von Willebrand Factor (VWF) regimens for different indications (on-demand, surgery and prophylaxis) in adult and pediatric participants with clinically severe congenital VWD.
The goal of this research is to more effectively measure and care for gum tissue health, prior to, during, and following a scheduled surgery. Traditionally, periodontal surgical procedures are measured using an instrument called the periodontal probe, which is a small ruler used inside the mouth. This instrument measures the quality and positioning of the oral soft tissue. However, this research study will utilize an intraoral scanner to take pictures and create a 3D image of the teeth and gums before and after surgery. This research will try to test the accuracy of an intraoral scanner, commonly used in restorative dentistry, as a new protocol of an existing practice to capture and measure the oral soft tissue before and after periodontal surgeries.
Periodontitis is a major cause of irreversible destruction of tissues leading to a loss of attachment between teeth and their supporting tissues. Several strategies are being tested experimentally to enhance periodontal regeneration, one of them being the use of stem cells.
In this study, eligible participants that are patients of the James B. Edwards College of Dental Medicine scheduled to have their teeth extracted. The teeth being extracted from patients during oral surgery, which otherwise would be discarded, will be donated for laboratory tests.