Evaluation of harm reduction messages to promote vaping among adult smokers Save

Date Added
September 9th, 2019
PRO Number
Pro00089381
Researcher
Bryan Heckman

List of Studies


Profiles_link
Keywords
Smoking
Summary

The US Food and Drug Administration (FDA) is beginning to regulate tobacco products in ways that promote the use of less harmful products, such as electronic cigarettes, among established adult smokers. In this study, we will evaluate whether using cigarette inserts that contain messages about lower harms form vaping vs smoking will be effective in getting smokers to switch from cigarettes to vaping. All participants will be given a JUUL starter kit and randomized to receive a 2 week supply of their preferred cigarette brand either without (control group) or with inserts that contain harm reduction messages (experimental group). We will evaluate whether the harm reduction messages influence attitudes and beliefs that are likely to promote smoking cessation and switching to e-cigarettes.

Institution
MUSC
Recruitment Contact
Asia Abad
843-792-9910
blissas@musc.edu

Comparison of leading e-cigarette product types on relative reinforcement value and tobacco use patterns among current smokers Save

Date Added
July 2nd, 2019
PRO Number
Pro00089701
Researcher
Tracy Smith

List of Studies

Silhouette
Keywords
Smoking
Summary

The goal of this research is to understand how different types of e-cigarettes affect tobacco use. Participants will either be assigned to a control group that does not receive an e-cigarette or be assigned to receive one of two different types of e-cigarettes to sample in the lab and at home. We will measure participants' smoking and smoke exposure during the study.

Institution
MUSC
Recruitment Contact
Tracy Smith
8437925164
smithtra@musc.edu

Neural mechanisms mediating appetitive regulation and smoking in nicotine addiction Save

Date Added
April 16th, 2019
PRO Number
Pro00086509
Researcher
Brett Froeliger

List of Studies


Profiles_link
Keywords
Smoking
Summary

Nicotine addiction is a chronic, relapsing brain disorder and although it is the leading cause of preventable premature death in the US, ~20% of adults smoke and among those that try to quit, the majority relapse.Research suggest that nicotine addiction disrupts the working in the brain involved in motivation and reward. The overarching goal of this proposal is to utilize clinical neuroscience to investigate the effects of Mindfulness Oriented Recovery Enhancement (MORE) on modifying behavior to help treat nicotine addiction.

Institution
MUSC
Recruitment Contact
Katherine Lastrapes
8437927865
lastrape@musc.edu

Mobile, remote, and individual-focused: Comparing breath carbon monoxide readings and abstinence in next generation monitors. Save

Date Added
March 8th, 2019
PRO Number
Pro00080107
Researcher
Erin Mcclure

List of Studies


Profiles_link
Keywords
Smoking
Summary

Currently recruiting cigarette smokers (any level of smoking) as well as healthy controls for a study comparing breath carbon monoxide (CO) monitors. Breath carbon monoxide can be used as an indicator of recent smoking and is measured by CO monitors. Breath CO can also be used to determine abstinence from smoking. There are several breath CO monitors commercially available, including a next generation model that connects directly to a smartphone and interfaces with a mobile application. Given the importance of comparability between different CO monitors, this study involves a comparison between three monitors to assess their agreement in CO readings and detecting abstinence from smoking. Participants will present for 10 brief study visits to complete CO breath tests using three different monitors. These study visits will last approximately 10-15 minutes.

Institution
MUSC
Recruitment Contact
Patrick Cato
843-792-4215
catop@musc.edu

Effects of filter ventilation on sensory response, smoking topography, and inhalation (COMET 2 2.1) Save

Date Added
October 31st, 2018
PRO Number
Pro00082861
Researcher
Kenneth Cummings

List of Studies

Silhouette
Keywords
Smoking
Summary

The aim is to assess the link between marketing proxies for filter ventilation (product descriptors, packaging) and risk beliefs. Ventilation is not directly promoted to consumers; rather its effects are communicated through the use of descriptive terms such as Light, Mild, and Low tar, often linked to lighter colors. Since the key terms have been restricted and replaced with others, it is important to determine which factors continue to contribute to false relative risk beliefs. We will conduct semi-structured interviews common in marketing research to test the influence of pack
descriptors and colors (as proxies for filter ventilation) on product risk perceptions and intention
to purchase..

Institution
MUSC
Recruitment Contact
Katherine Lastrapes
843-882-7196
lastrape@musc.edu

An fMRI pilot study of the effects of Clavulanic Acid on cigarette withdrawal Save

Date Added
September 18th, 2018
PRO Number
Pro00078213
Researcher
Brett Froeliger

List of Studies


Profiles_link
Keywords
Smoking
Summary

The broad objective of this proposal is to use fMRI methods to conduct preliminary investigation of the effects of Clavulanic Acid on neurocognition and smoking withdrawal in abstinent cigarette smokers. This project will involve collecting data from a total of approximately 40 adult smokers.

Institution
MUSC
Recruitment Contact
Shannon Powers
843-882-7196
powerssh@musc.edu

Impact of e-cigarette characteristics on reinforcement and tobacco use patterns among current smokers Save

Date Added
September 4th, 2018
PRO Number
Pro00081069
Researcher
Tracy Smith

List of Studies

Silhouette
Keywords
Smoking
Summary

The purpose of this project is to understand how different e-cigarettes influence their likeability and use among current smokers who try using e-cigarettes. Participants will receive an e-cigarette to sample over a three week period. During this time period they will complete daily electronic diaries and weekly lab visits. The results from this information will help us understand how different types of e-cigarettes are likely to influence cigarette and e-cigarette use.

Institution
MUSC
Recruitment Contact
Tracy Smith
8437925164
smithtra@musc.edu

A Pilot Translational Study of Varenicline Sampling to Promote Treatment Engagement and Smoking Cessation Save

Date Added
July 3rd, 2018
PRO Number
Pro00078289
Researcher
Matthew Carpenter

List of Studies


Profiles_link
Keywords
Smoking
Summary

This is a research study to find out if a smoking cessation medication, varenicline, is effective when given to smokers, remotely, as a one-time, 4-week sample.

Participants will either receive a sample of varenicline, or not. This will be decided randomly. The medicine will be mailed to participants and participants will complete 5 study contacts in addition to completing daily diaries for the first 4 weeks of the study. Participation will last 3 months.

Varenicline is a well-established medication that helps smokers quit. If participants are in the group that receives varenicline, it may help them too. But they are not required to use it, and it is completely up to them to use as they wish. Side effects from taking varenicline might include insomnia, headache, or nausea. Some individuals report negative changes in mood. Most smokers who use varenicline do not experience these symptoms.

Institution
MUSC
Recruitment Contact
Lisa Coles
843-876-2291
colesl@musc.edu

Enhancing self-regulation by altering memories that increase risk of relapse among smokers: A translational clinical neuroscience study of a novel medication Save

Date Added
June 5th, 2018
PRO Number
Pro00076669
Researcher
Michael Saladin

List of Studies


Profiles_link
Keywords
Drug Studies, Smoking
Summary

The proposed study is looking to recruit smokers over the age of 18 to complete a four visit study. Participants will be randomized to receive either rapamycin (sirolimus) or a placebo at the second visit to assess potential effects on craving and relapse. Four study visits will be completed over the course of about three weeks.

Institution
MUSC
Recruitment Contact
Brittany Frasier
843-792-6984
frasibri@musc.edu

Examining the effects of Theta Burst Stimulation on corticothalamic mediated inhibitory control and smoking relapse vulnerability Save

Date Added
February 20th, 2018
PRO Number
Pro00074836
Researcher
Brett Froeliger

List of Studies


Profiles_link
Keywords
Brain, Smoking
Summary

MUSC is recruiting adult cigarette smokers (18 to 65) who are interested in participating in a research study examining the effects of brain stimulation on neural activity and behavior. This study consists of 4 visits over the course of 2-3 weeks. Qualified individuals will be compensated for participation.

Institution
MUSC
Recruitment Contact
Makayla Joy Gibson
(803) 814-4017
mjgibson@email.sc.edu

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