Specimen Procurement for NeuMoDx™ Chlamydia trachomatis and Neisseria gonorrhoeae (CT/NG) Assay Evaluation Save

Date Added
March 6th, 2019
PRO Number
Pro00084622
Researcher
Gweneth Lazenby

List of Studies


Profiles_link
Keywords
Obstetrics and Gynecology
Summary

The purpose of this research is to provide the sponsor vaginal and urine samples that the clinician has collected and the subject has self collected in order to study a new test being developed for the detection of Chlamydia trachomatis and
Neisseria gonorrhoeae.

Institution
MUSC
Recruitment Contact
Jesslyn Payne
843-792-9302
paynej@musc.edu

Web-Based Treatment for Perinatal Opioid Use Disorder Save

Date Added
March 2nd, 2019
PRO Number
Pro00085580
Researcher
Constance Guille

List of Studies


Profiles_link
Keywords
Mental Health, Obstetrics and Gynecology, Pregnancy, Psychiatry, Substance Use, Women's Health
Summary

This purpose of this research study is to collect feedback from participants about a web-based program for opioid misuse and opioid use disorder. Participants will be asked to review web-based content and take part in focus groups (group discussions) and individual interviews to provide feedback on the content. The study team is looking for pregnant women or women who have been pregnant in the past 2 years who misuse opioids or have opioid use disorder, as well as obstetric providers who treat pregnant women with opioid misuse and opioid use disorder to participate.

Institution
MUSC
Recruitment Contact
Edie Douglas
843-792-0403
douglaed@musc.edu

Changes in Optic Nerve Sheath Diameter in Preeclamptic patients with Severe Features by Neurologic Criteria versus Diagnosis Without Neurologic Criteria, Compared to Controls. Save

Date Added
November 7th, 2018
PRO Number
Pro00078977
Researcher
Mary Sterrett

List of Studies

Silhouette
Keywords
Central Nervous System, Hypertension/ High Blood Pressure, Non-interventional, Obstetrics and Gynecology, Pregnancy, Women's Health
Summary

Preeclamptic patients will have an ultrasound done of their eyes, to look at the size of the nerve behind the eye. We will also recruit women without preeclampsia to be a comparison group.

Institution
MUSC
Recruitment Contact
Mary Sterrett
8434940554
sterretm@musc.edu

A Randomized Controlled Trial of Playing "The Most Relaxing Song in the World" During Labor Epidural Placement and its Effects on Anxiety and Satisfaction. Save

Date Added
October 3rd, 2018
PRO Number
Pro00078958
Researcher
David Gutman

List of Studies

Silhouette
Keywords
Obstetrics and Gynecology
Summary

We propose to play the song "Weightless" during epidural placement on an iPhone set to medium volume. The song (all 6 continual parts) is 43 minutes long and will be started just before epidural placement and stopped just after end of procedure. The control group will be expectant mothers who do not have "Weightless" playing during their epidural placement. The goal is to determine if playing "the most relaxing song in the world" helps to reduce laboring parturients anxiety and improve their overall satisfaction with the experience.

Institution
MUSC
Recruitment Contact
Christine Aanstoos
843-792-1869
aanstoos@musc.edu

A randomized, parallel-group, double-blind and open-label, placebo-controlled, multicenter study to assess the efficacy and safety of vilaprisan in subjects with uterine fibroids Save

Date Added
May 22nd, 2018
PRO Number
Pro00077125
Researcher
David Soper

List of Studies


Profiles_link
Keywords
Obstetrics and Gynecology
Summary

Bayer is studying an investigational drug, Vilaprasin, in women who have been diagnosed with uterine fibroids, to treat heavy menstrual bleeding. Subjects will take an oral medication or placebo. Subjects will remain in the study for about 16 months and involves up to 8 visits.

Institution
MUSC
Recruitment Contact
Betty Oswald
843-792-0347
oswaldbw@musc.edu

Comparison of Length of Stay for Infants with GBS Unknown Mothers with Adequate vs Inadequate Treatment Save

Date Added
April 6th, 2018
PRO Number
Pro00077255
Researcher
Rachel Sigrest

List of Studies

Keywords
Children's Health, Disease Prevention, Infant, Non-interventional, Obstetrics and Gynecology, Pediatrics, Pregnancy, Women's Health
Summary

The primary investigators/residents have noted during clinical rotations that a significant number of GBS unknown mothers at SRHS are being treated with intrapartum antibiotics even without the presence of risk factors, presumably to decrease postpartum/neonatal length of stay.
Our study, a retrospective chart review, will determine whether or not length of stay is affected by treating GBS unknown mothers with intrapartum antibiotics in the absence of the aforementioned risk factors.
Potential benefits include the cost-effectiveness of decreased length of stay for these patients as well as decreased exposure to nosocomial infections for neonates. However, antibiotic stewardship and patient safety are also considerations. Another potential option for these patients is rapid GBS testing with PCR which can provide results in 1-2 hours compared with 24-48 hours for the standard culture. PCR is not currently available at SMC.

Institution
Spartanburg
Recruitment Contact
Rachel Sigrest
8643800885
racheljames1985@gmail.com

An open-label, parallel-group, randomized, multicenter study to assess the safety and efficacy of vilaprisan in subjects with uterine fibroids versus standard of care Save

Date Added
January 9th, 2018
PRO Number
Pro00068023
Researcher
David Soper

List of Studies


Profiles_link
Keywords
Obstetrics and Gynecology
Summary

Bayer is studying an investigational drug, Vilaprasin, in women who have been diagnosed with uterine fibroids vs standard treatment.

Institution
MUSC
Recruitment Contact
Jesslyn Payne
843-792-9302
paynej@musc.edu

Comparison of 0.1 and 0.05mg intrathecal morphine when administered with a multimodal pain regimen for post-cesarean analgesia: a single center, prospective, randomized, single-blinded trial. Save

Date Added
December 19th, 2017
PRO Number
Pro00072393
Researcher
Kathryn Bridges

List of Studies


Profiles_link
Keywords
Obstetrics and Gynecology, Pain, Surgery
Summary

This study will compare 0.1mg and 0.05mg of spinal morphine for postoperative pain after scheduled, elective Cesarean delivery. All patients will receive a spinal anesthetic (single injection in the lower back to numb patients from the waist down) for operative anesthesia and will be
randomized into one of two groups: (group 1) 0.1mg spinal morphine and (group 2) 0.05mg spinal morphine. This will be a randomized, single blinded study.

Institution
MUSC
Recruitment Contact
Wanda Jones
843-792-1869
joneswr@musc.edu

Prospective, Non-Interventional/Observational Registry of US Uterine Fibroids Patients (Capture-US) Save

Date Added
May 16th, 2017
PRO Number
Pro00065519
Researcher
David Soper

List of Studies


Profiles_link
Keywords
Obstetrics and Gynecology
Summary

This study is try to understand current patients with fibroids and there choices for management. We will follow women through their journey and obtain patient reported outcomes, through questionnaire's, following their current therapies for Uterine Fibroids, including symptoms, quality of life, work productivity impact, and satisfaction.

Institution
MUSC
Recruitment Contact
Jordyn DeMartino
843-792-0349
demartij@musc.edu

Chronic Hypertension and Pregnancy (CHAP) Project A Pragmatic Multicenter Randomized Trial Antihypertensive Therapy for Mild Chronic Hypertension during Pregnancy Save

Date Added
April 18th, 2017
PRO Number
Pro00063098
Researcher
Eugene Chang

List of Studies


Profiles_link
Keywords
Obstetrics and Gynecology
Summary

The purpose of this study is to evaluate the safety and benefits of treating mild chronic hypertension (CHTN), or high blood pressure, with medication during pregnancy vs non treatment. Medication prescribed is medication currently approved to treat severe CHTN.

Institution
MUSC
Recruitment Contact
Laura Columbo
843-792-0316
columbol@musc.edu

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