Empowering Rural Teens through Photovoice to Influence the Health of their Community Save

Date Added
July 28th, 2017
PRO Number
Pro00067937
Researcher
Michelle Nichols
Keywords
Adolescents, Disease Prevention, Environmental Factors, Ethnicity and Disease, Exercise, Minorities, Non-interventional, Nutrition, Obesity
Summary

This study will recruit adolescents who are enrolled in a Teen Health Careers Program to participate in a community-engaged study. This study will seek to understand the barriers and facilitators to physical activity and nutritious foods throughout their daily lives. Adolescents will use take digital images to capture aspects of their daily lives using photography.

Institution
MUSC
Recruitment Contact
Michelle Nichols
(843) 792-1802
nicholmg@musc.edu

Evaluation of the CytoRADx SystemTM as a Biodosimeter for Special Human Populations Save

Date Added
July 14th, 2017
PRO Number
Pro00067066
Researcher
Gary Headden
Keywords
Blood Disorders, Children's Health, Environmental Factors, HIV / AIDS, Non-interventional, Pediatrics
Summary

This is a study to develop a test for radiation exposure in the event of a nuclear event such as the detonation of a nuclear device or widespread radiation exposure. We will collect blood samples from a variety of different types of human subjects whose current medical status could possibly have an effect on the results of the test, such as trauma, burns, infections or a damaged immune system or young children. The goal is to ensure that these conditions do not affect the results of the test.

Institution
MUSC
Recruitment Contact
Robert Houck
(843) 792-3576
houckr@musc.edu

Establishing a Baseline Health Assessment in Economically Distressed Communities of North Charleston, SC Save

Date Added
November 14th, 2016
PRO Number
Pro00056615
Researcher
Michelle Nichols
Keywords
Environmental Factors, Healthy Volunteer Studies
Summary

Health outcomes resulting from chronic exposures to port activities include increased cancer, diabetes, cardiovascular disease, and respiratory disease. The proposed research is significant because it will allow adverse health effects of anticipated air pollutants resulting from increased diesel emissions associated with port activities to be assessed. The research team has developed with community input a health survey from existing, validated survey instruments to self-report health outcomes including cancer, diabetes, cardiovascular and lung diseases.

Institution
MUSC
Recruitment Contact
Michelle Nichols
843-792-1802
nicholmg@musc.edu

A Time-Controlled Examination of the Effects of Repeated Measures Design on fMRI Experimental Tasks Save

Date Added
January 20th, 2015
PRO Number
Pro00040073
Researcher
Brett Froeliger
Keywords
Brain, Central Nervous System, Environmental Factors, Nervous System, Psychiatry, Smoking
Summary

The purpose of this study is to examine the effects of experimental design on brain responses.

Institution
MUSC
Recruitment Contact
Aaron Haas
843-882-7196
haas@musc.edu

Alpha-1 Foundation Clinical Resource Center (CRC) Research Registry Save

Date Added
November 18th, 2014
PRO Number
Pro00026071
Researcher
Charlie Strange
Keywords
Asthma, Breathing, Environmental Factors, Genetics, Liver, Lung, Pulmonary, Rare Diseases, Shortness of Breath
Summary

The purpose of the Alpha-1 Foundation Clinical Resource Center (CRC) Research Registry is to collect and store medical information from individuals with alpha-1 antitrypsin deficiency (AATD or Alpha-1) or individuals that carry a deficient Alpha-1 gene. The Registry will collect medical information on your disease and diagnosis. This information will include family history, lung and liver symptoms, and exposure to cigarette smoke, dusts and fumes.The goal of this project is to obtain and share information that defines the natural history of alpha-1 antitrypsin deficiency. Biological samples from either blood or tissue may be collected and stored as part of this research. This project will assemble a library of these biological samples, some of which will be saved at MUSC.

Institution
MUSC
Recruitment Contact
Eryn Varano
877-886-2383
alphaone@musc.edu

A Pilot Study Evaluating Racial Disparity, Environmental Toxin Exposure and Regulation of Anti-Inflammatory Mediators as Risk Factors for Endometrial Carcinogenesis Save

Date Added
May 22nd, 2014
PRO Number
Pro00030149
Researcher
Whitney Graybill
Keywords
Cancer, Environmental Factors
Summary

The purpose of this study is to determine if environmental toxin exposure differs in African American women as compared to White women with endometrial cancer and to evaluate the relationship between demographic variables and toxin level.

Institution
MUSC
Recruitment Contact
Tamara Jenkins
843-792-6992
saundert@musc.edu

Structured Life Reviews in Adults with Sickle Cell Disease Save

Date Added
March 14th, 2014
PRO Number
Pro00032118
Researcher
Shannon Hudson
Keywords
Blood Disorders, Environmental Factors, Non-interventional
Summary

Structured life reviews are a series of interviews during which the interviewer asks questions about a person's life experiences from birth to the present. During this study, we will conduct structured life reviews with adults with sickle cell disease. We will ask questions about life transitions and health care utilization.

Institution
MUSC
Recruitment Contact
Shannon Phillips
843-792-9379
hudsonsm@musc.edu

The Multidisciplinary Clinical Research Center for Rheumatic Diseases in African Americans Save

Date Added
January 15th, 2013
PRO Number
Pro00021985
Researcher
Gary Gilkeson
Keywords
Autoimmune disease, Environmental Factors, Ethnicity and Disease, Genetics, Healthy Volunteer Studies, Lupus, Minorities, Rare Diseases, Scleroderma
Summary

Systemic lupus erythematosus (lupus; SLE) and Systemic Sclerosis (scleroderma; SSc) are relatively rare rheumatic diseases that disproportionately impact the African American community, and particularly African American women. The causes of lupus and scleroderma are unknown, but thought to include both genetic and environmental factors. We are enrolling lupus and scleroderma patients, and healthy control subjects. This is not a drug study. The purpose of this study is to better understand the factors that predispose people to develop lupus and scleroderma. Information about medical, social and family history, medications, physical exam findings, and laboratory tests will be collected for analysis. This study will involve approximately 910 volunteers.

Institution
MUSC
Recruitment Contact
Stephanie Slan
843-792-8997
slans@musc.edu

Risk Factor Analysis in Amyotrophic Lateral Sclerosis Save

Date Added
February 6th, 2012
PRO Number
Pro00014882
Researcher
Angela Malek
Keywords
Environmental Factors, Nervous System
Summary

This research is being conducted to investigate the association of personal, environmental, and occupational risk factors and ALS. A web-based survey that includes questions about demographics, medical history, family history of neurological disorders, hobbies, military history, smoking, physical activity, residential history, and occupational history, etc. will be completed by ALS patients as well as controls without ALS to compare differences among the two groups.

Institution
MUSC
Recruitment Contact
Angela Malek
843-792-9590
malek@musc.edu

Systemic Lupus Erythematosus in Gullah Health (SLEIGH) Save

Date Added
October 5th, 2009
IRB Number
10852
Researcher
Diane Kamen
Keywords
Autoimmune disease, Children's Health, Environmental Factors, Ethnicity and Disease, Healthy Volunteer Studies, Immune System, Joint, Kidney, Lupus, Minorities, Non-interventional, Vitamin D, Women's Health
Summary

The Systemic Lupus Erythematosus (SLE) in Gullah Health, or SLEIGH, study is an observational study enrolling African Americans from the Sea Island communities of South Carolina and Georgia. We are enrolling patients, family members of patients, and unrelated community members. SLE is a potentially severe disease that can affect the entire body. SLE is more common in African Americans than Caucasians. The main purpose of this study is to find genes that, along with factors from the environment, result in the development of SLE. Volunteers in SLEIGH will be asked to answer questions about their health and have blood and urine collected for tests. After the first visit there may be one additional visit 2 or more years later. This is not a drug study.

Institution
MUSC
Recruitment Contact
Stephanie Slan
843-792-8997
slans@musc.edu

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