PREEMPT CRC: PREvention Employing a Multiomics Plasma-based Test for ColoRectal Cancer Save

Date Added
June 22nd, 2020
PRO Number
Pro00099252
Researcher
Don Rockey

List of Studies


Profiles_link
Keywords
Aging, Cancer/Other, Colonoscopy, Digestive System, Disease Prevention, Men's Health, Prostate
Summary

The Sponsor of this research study is trying to develop a new experimental diagnostic blood test that may help detect colorectal cancer and other diseases. A diagnostic test identifies a specific disease or condition. Experimental means the test has not received approval by the United States Food and Drug Administration (FDA) for sale.
The main goal of this research study is to collect health information and blood samples from people who are going to have a standard-of-care screening colonoscopy. The blood samples along with other health information from patients who take part in the study may help the Sponsor develop new diagnostic tests that may help detect cancer or other diseases in other patients in the future.

Institution
MUSC
Recruitment Contact
Megan Bickford
843-876-8439
bickfome@musc.edu

Reduced Pressure Reaming versus Standard Reaming for the Treatment of Impending Pathologic Femur Fractures Save

Date Added
January 16th, 2018
PRO Number
Pro00063851
Researcher
Lee Leddy

List of Studies


Profiles_link
Keywords
Bone, Cancer, Cancer/Lymphoma, Cancer/Myeloma, Cancer/Other, Cancer/Sarcoma, Surgery
Summary

This study is for patients that have suffered a femur fracture due to metastatic cancer. The standard of care for this type of fracture is to stabilize the bone with an intramedullary nail. When preparing the femur for the nail, pressure can cause fat to enter the bloodstream and travel to the heart, causing heart and lung complications. The procedure being investigated in this study is called reduced pressure reaming. In this procedure the surgeon will use a device with suction when preparing the bone for the nail in order to decrease pressure and decrease the amount of fat that enters the bloodstream. Patients will be randomly assigned to either the standard preparation (standard reaming), or the reduced pressure preparation (reduced pressure reaming). After surgery, both treatment groups will followed according to standard practices at 2 weeks, 6 weeks, 3 months, and 6 months.

Institution
MUSC
Recruitment Contact
Robert McClam
843-792-7238
mcclamr@musc.edu

A 5-year Longitudinal Observational Study of the Natural History and Management of Patients with Hepatocellular Carcinoma Save

Date Added
February 28th, 2017
PRO Number
Pro00062918
Researcher
David Koch

List of Studies


Profiles_link
Keywords
Cancer, Cancer/Gastrointestinal, Cancer/Other, Digestive System, Genetics, Liver, Obesity, Weight Control
Summary

TARGET-HCC is a 5-year, longitudinal, observational study of the natural history and management of patients with HCC. The study will address important clinical questions that remain unanswered in the management of HCC with a unique research registry of participants with HCC from academic and community real-world practices. TARGET-HCC is disease focused, not drug specific, which allows for continuous acquisition of real-world evidence regarding the natural history, management, and outcomes of treatment with current therapies and new treatments that may be utilized in usual clinical practice.

Institution
MUSC
Recruitment Contact
Francis Beylotte
843-876-4273
beylott@musc.edu

WFU 97115 - A Phase III Prospective Randomized Trial of Acupuncture for Treatment of Radiation-Induced Xerostomia in Patients with Head and Neck Cancer Save

Date Added
January 19th, 2016
PRO Number
Pro00050521
Researcher
Jeffrey Giguere

List of Studies

Keywords
Cancer, Cancer/Head & Neck, Cancer/Other
Summary

This research study is for patients who have xerostomia (dry mouth) caused by radiation treatment received in the past for cancer.

The purposed of this study is to determine whether or not acupuncture can improve symptoms related to dry mouth due to head/neck radiotherapy.

Eligible participants will be randomized (assigned by a computer) to one of three groups: the standard of care group (group where usual care for dry mouth is given) or to one of two acupuncture groups. One of the acupuncture treatment approaches has not been studied in a large randomized trial and may not target symptoms. Each group is equally important in the trial. All groups play an important role in helping to determine if acupuncture helps decrease symptoms of dry mouth.

Participation will last up to 9 months. About 240 people will be enrolled in this trial.

Institution
Greenville
Recruitment Contact
Gina Norris
864-242-2762
GNorris@ghs.org

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