REVAMP Study (REmodeling the Left Ventricle with Atrial Modulated Pacing) Save

Date Added
August 8th, 2017
PRO Number
Pro00067879
Researcher
Sheldon Litwin

Silhouette
Keywords
Heart
Summary

The REVAMP Clinical Study is a feasibility study in heart failure with preserved ejection fraction (HFpEF) patients who have normal to small left ventricular volumes and evidence of hypertrophy. The pacemaker Sleep function will be used in order to deliver a 5 hour block of sustained pacing at 100 bpm during the night for 4-8 weeks. The purpose is to investigate whether this elevated pacing therapy is tolerated and whether there is a signal of efficacy.

If tolerated the idea is that this will promote LV dilation, which will reduce stiffness in the heart and improve diastolic filling in HFpEF patients that have thickened ventricular walls.

Institution
MUSC
Recruitment Contact
Kayla Moses
843-792-5873
moseska@musc.edu

REDUCE LAP-HF RANDOMIZED TRIAL II: A study to evaluate the Corvia Medical, Inc. IASD® System II to REDUCE Elevated Left Atrial Pressure in Patients with Heart Failure Save

Date Added
May 9th, 2017
PRO Number
Pro00065245
Researcher
Sheldon Litwin

Silhouette
Keywords
Cardiovascular, Heart
Summary

The purpose of this study is to evaluate the potential effectiveness, outcomes, and safety (before, during, and after study procedures) of the investigational device in the treatment of subjects with heart failure symptoms and relatively normal pumping of the heart. The device is called the IASD system II and it is permanently implanted in the heart to reduce in the increased pressure by creating a small opening between the two upper chambers of the heart. It will be a randomized, single blind (subject) trial. Subjects will be followed for two years and then annually for 3 years for a total of 5 years after implantation.

Institution
MUSC
Recruitment Contact
Renee Baxley
843-792-1105
baxleyr@musc.edu

Weight Loss in Patients with Heart Failure and Preserved Ejection Fraction: A Supervised Diet and Lifestyle Intervention (WTLSSCHF) Save

Date Added
July 21st, 2015
PRO Number
Pro00040117
Researcher
Sheldon Litwin

Silhouette
Keywords
Cardiovascular, Weight Control
Summary

This is a study in which subjects who have heart failure and normal heart pumping function are enrolled in a weight management program. The study will examine the subject's symptoms, exercise capacity and bloodwork to see if there is improvement while on the weight management program and as they transition to a healthly diet and lifestyle.

Institution
MUSC
Recruitment Contact
Lindsey Stewart
(843) 792-1238
stew@musc.edu

Change_preferences

-- OR --

Create_login