The TRANSFORM network is focused on improving child health outcomes in SC through research on conditions of highest priority for future generations. These include conditions like asthma, autism, diabetes, obesity and early childhood outcomes. To accelerate research study recruitment activities for future projects that TRANSFORM sites may participate in, the TRANSFORM network sites will create a research recruitment registry of families interested in volunteering for research. Participants will enter their own as well as their child(ren)'s information into the electronic registry which can be used to identify people to contact for future studies.
This study is for adults, ages 18 to 65, who have been diagnosed with Autism Spectrum Disorder and have symptoms of Major Depressive Disorder. The treatment used will be Transcranial Magnetic Stimulation (TMS), a non-invasive form of brain stimulation that is FDA-approved for treating depression in adults. The investigators aim to treat participants' depressive symptoms and also study the possible positive impact of TMS on Autism symptoms and irritability associated with autism. In addition, the investigators will obtain imaging studies of the participants to learn more about the impact of TMS on the brain's structure and function in adult subjects with Autism. This is an open-label pilot study, meaning that each participant will receive the same treatment and that there is no 'placebo' treatment given for any of the study participants.
This pilot project is a collaborative effort between the Autism Wonders program at Greenville Health Systems and the Department of Psychology at the University of South Carolina. The overarching objective of the project is to clarify the relationship of ASD diagnosis and the presence of anxiety symptoms in a sample of children being evaluated for an ASD diagnosis. The project will use a multi-method approach to the assessment of ASD and anxiety symptoms, drawing from behavioral observation, gold-standard diagnostic measures, and parent-report questionnaires.
We are recruiting mothers of children with typical development, autism, or fragile X syndrome.
This study focuses on parental experiences and normal individual differences that may influence child language development. The broader goal of the study is to understand which family experiences support language development in children who have neurodevelopmental disabilities, such as autism. We are recruiting families who have children who are typically developing, have autism, or have fragile X syndrome.