A Phase 2a, Single-Blind, Placebo-Controlled, Parallel-Group Study to Assess Safety, Tolerability, and Pharmacokinetics of Brensocatib Tablets in Adults With Cystic Fibrosis

Date Added
March 17th, 2022
PRO Number
Pro00117670
Researcher
Patrick Flume

List of Studies


Keywords
Cystic Fibrosis, Lung, Pulmonary
Summary

This is an experimental, single-blind, randomized, placebo-controlled, clinical research study of a study drug called brensocatib. The goal of the study is to find a safe and accepted brensocatib dose in people with cystic fibrosis. This study will also help to learn the pharmacokinetic (or "PK") and pharmacodynamic (or "PD") properties of brensocatib. As the Sponsor (Insmed Incorporated) wants to assess the effect of brensocatib in participants with cystic fibrosis, samples of sputum and blood will be collected in this study. About 36 to 48 adults will take part in this study and the duration of this study is expected to be 84 days or less.

Institution
MUSC
Recruitment Contact
Zerlinna Teague
(843) 792-0965
shannonz@musc.edu