The objective of this clinical study is to assess how safe and effective the LibAirtyTM airway clearance system, in comparison to HFCWO therapy (The Vest), in subjects with bronchiectasis. The LibAirtyTM Airway Clearance System is designed to assist in the loosening and elimination of mucus from the lungs, The system includes 1) a control unit with an air compressor and 2) an inflatable vest. If you enroll in this study, you will be asked to attend four study visits over approximately four weeks, potentially be treated with two different airway clearance systems and to complete study questionnaires and pulmonary function tests.