Glaucoma is the leading cause of permanent blindness in the world, often due to the intraocular pressure in your eye (IOP) becoming too high. Cataracts are the cloudy lenses inside your eye that are common after age 40 and often require surgery to replace the cloudy lens with an intraocular implant (IOL). This study will evaluate the safety and IOP-lowering effectiveness of the DF12 Canaloplasty and Trabeculotomy Surgical System. This device combines two glaucoma surgical procedures (Canaloplasty and Trabeculotomy) in patients that are having their cataracts removed. The endpoint for this study is the reduction in IOP without the use of topical (often eye drops) or oral glaucoma medications at 12 months.

This study compares two common laser treatments used to lower eye pressure in participants with glaucoma or high eye pressure. Both procedures, Selective Laser Trabeculoplasty (SLT) and Direct Selective Laser Trabeculoplasty (DSLT), are established standard-of-care medical treatments. Participants are randomly assigned by a computer to receive one of these two lasers to compare efficacy and safety. To maintain clinical consistency, both eyes of each participant receive the same assigned laser treatment during a single visit. There are no additional research-only appointments required beyond standard clinical care. The study team reviews medical records from the participants' standard 3, 6, and 12-month clinical follow-up visits. This research aims to help clinicians understand which treatment is more effective or efficient for future use. Participation is entirely voluntary and does not impact the quality of medical care provided at the institution.