Long-Term Nicotine Treatment of Mild Cognitive Impairment

Date Added
August 3rd, 2021
PRO Number
Pro00112159
Researcher
Jacobo Mintzer

List of Studies


Keywords
Aging, Alzheimers, Brain, Dementia, Drug Studies, Memory Loss
Summary

The purpose of the study is to see if daily use of nicotine patches will slow or reverse memory loss in participants with Mild cognitive impairment, an early stage of mental decline associated with Alzheimer's disease. Nicotine may mimic natural chemicals in the brain that play a crucial role in memory function, and previous studies have shown that nicotine may improve attention, learning, and memory. In this study, participants will receive either nicotine (up to 21mg/day, the standard dosage of a nicotine patch) or placebo for 2 years to see if these improvements in brain function can be observed over a longer period.

Institution
MUSC
Recruitment Contact
Allison Lapp
843-608-1950 x 1109
allisonlapp@lcvresearch.org

Anti-Amyloid Treatment in Asymptomatic Alzheimer's Disease (A4) Study

Date Added
July 21st, 2021
PRO Number
Pro00112140
Researcher
Jacobo Mintzer

List of Studies


Keywords
Aging, Alzheimers, Brain, Dementia, Drug Studies, Memory Loss
Summary

The purpose of this study is to test whether an investigational drug called solanezumab can slow the progression of memory problems associated with brain amyloid (protein that forms plaques in the brains of people with Alzheimer Disease [AD]).

Institution
MUSC
Recruitment Contact
Allison Lapp
843-608-1950 x 1109
allisonlapp@lcvresearch.org

Apathy in Dementia Methylphenidate Trial 2 (ADMET 2)

Date Added
September 23rd, 2015
PRO Number
Pro00043151
Researcher
Jacobo Mintzer

List of Studies


Keywords
Aging, Alzheimers, Brain
Summary

With this research study, we want to learn if methylphenidate (RitalinĀ® and others) helps people with Alzheimer's disease and apathy (lack of interest or concern for things that others find moving or exciting).

Institution
MUSC
Recruitment Contact
Allison Lapp
843-724-2302
Allison.Lapp@rsfh.com



-- OR --