This study will involve taking one or two medications already approved by the Food and Drug Administration (FDA) for treatment of type 2 diabetes to learn more about which diabetes medications are the best for lowering the risk of heart and kidney disease in individuals with type 2 diabetes who are at least 40 years old. Participation includes about 8 study visits over a period of 72 months, which can be performed over the phone remotely or during normal standard of care clinic visits. Participants will be compensated for their time and participation in this research study.

The purpose of this research study is to learn about time restricted feeding and breast cancer risk markers in post-menopausal women with prediabetes. Time restricted feeding involves changing the daily eating period for consumption of meals and snacks.

Participants will be randomly assigned to either the time restricted feeding group with a daily eating period of 8 hours or the control group with a daily eating period of greater than or equal to 12 hours. There are 2 in-person study visits to have blood, urine and vital signs collected, 1 remote or phone visit with study coordinator and 8 remote or phone visits with a psychologist or dietician to assist with the eating schedule . The study will take about 3 1/2 months. There is no cost to participate. Compensation for the 2 in-person visits is provided..