Direct measurement of motor cortical responses to transcranial direct current stimulation Save

Date Added
May 15th, 2018
PRO Number
Pro00073545
Researcher
Nathan Rowland

Silhouette
Keywords
Brain, Central Nervous System, Movement Disorders, Muscle, Nerve, Nervous System, Parkinsons, Surgery
Summary

Transcranial direct current stimulation (tDCS) has shown the potential to improve symptoms in patients with Parkinson's disease, however its effects have not been consistent in randomized studies to date, limiting widespread adoption of this technology. A critical gap in our knowledge is a detailed understanding of how tDCS affects motor areas in the brain. We propose using tDCS while recording directly from motor cortex using subdural electrocorticography (sECoG) in Parkinson's patients undergoing deep brain stimulation surgery. We expect this novel approach to broaden our understanding of tDCS application in Parkinson's disease and possibly lead to therapeutic advances in this population.

Institution
MUSC
Recruitment Contact
Sanicqua Robinson Smalls
843-792-8553
robinsst@musc.edu

Utilization of quadratus lumborum block for postoperative analgesia following hip arthroscopy: A prospective, randomized clinical trial. Save

Date Added
March 20th, 2018
PRO Number
Pro00076191
Researcher
Sylvia Wilson

Silhouette
Keywords
Surgery
Summary

The purpose of this research study is to find out if a nerve block named quadratus lumborum block (QL) can provide better pain relief than having no nerve block for patients having their surgery on their hip through several small incisions while the surgeon looks with a camera (hip arthroscopy).

Institution
MUSC
Recruitment Contact
Wanda Jones
843-792-1869
joneswr@musc.edu

Quadratus Lumborum versus Transversus Abdominus Plane Nerve Block: A Comparison in Regional Anesthesia Techniques with an Enhanced Recovery After Surgery Pathway Save

Date Added
March 20th, 2018
PRO Number
Pro00075597
Researcher
Renuka George

Silhouette
Keywords
Surgery
Summary

The purpose of this study is to compare post operative pain control with the use of two nerve blocks, quadratus lumborum and transversus abdominis plane block, after elective laparoscopic abdominal surgery.

Institution
MUSC
Recruitment Contact
Wanda Jones
843-792-1869
joneswr@musc.edu

Safety and Efficacy of the Tao Facemask for Positive Pressure Ventilation in the Patients with Significantly Elevated BMIs Save

Date Added
February 20th, 2018
PRO Number
Pro00073465
Researcher
Tod Brown

Silhouette
Keywords
Surgery
Summary

This study will compare the safety and effectiveness of a new facemask, the Tao mask, as compared to the standard mask for manual ventilation of patients with BMIs of 40 or greater who are undergoing elective surgery. The Tao mask and the standard mask will both be used for each patient but the order of evaluating the masks will be randomized.

Institution
MUSC
Recruitment Contact
Wanda Jones
843-792-1869
joneswr@musc.edu

Quadratus lumborum block versus transversus abdominus plane block for pain management after donor nephrectomy Save

Date Added
January 16th, 2018
PRO Number
Pro00073925
Researcher
Eric Bolin

Silhouette
Keywords
Surgery
Summary

The purpose of this study is to compare post operative pain with the use of two blocks - quadratus lumborum block and transversus abdominis plane block after laparoscopic donor nephrectomy patients.

Institution
MUSC
Recruitment Contact
Wanda Jones
843-876-1869
joneswr@musc.edu

A Multicenter, Observational Trial of Surgical Stabilization of Rib Fractures in Patients with Severe, Non-flail Fracture Patterns (CWIS NON FLAIL) Save

Date Added
January 16th, 2018
PRO Number
Pro00073320
Researcher
Evert Eriksson

Silhouette
Keywords
Surgery
Summary

Recently, surgical stabilization of rib fractures, which involves an operation to place thin titanium plates across the fractures, has been shown to improve outcomes in patients with several fractures on the same ribs of the chest wall. Many surgeons who perform this operation regularly also believe that it will benefit patients with other severe forms of rib fractures, specifically 3 or more severely displaced fractures without multiple fractures of the same rib.

Institution
MUSC
Recruitment Contact
Evert Eriksson
843-792-3780
eriksson@musc.edu

Reduced Pressure Reaming versus Standard Reaming for the Treatment of Impending Pathologic Femur Fractures Save

Date Added
January 16th, 2018
PRO Number
Pro00063851
Researcher
Lee Leddy

Silhouette
Keywords
Bone, Cancer, Cancer/Lymphoma, Cancer/Myeloma, Cancer/Other, Cancer/Sarcoma, Surgery
Summary

This study is for patients that have suffered a femur fracture due to metastatic cancer. The standard of care for this type of fracture is to stabilize the bone with an intramedullary nail. When preparing the femur for the nail, pressure can cause fat to enter the bloodstream and travel to the heart, causing heart and lung complications. The procedure being investigated in this study is called reduced pressure reaming. In this procedure the surgeon will use a device with suction when preparing the bone for the nail in order to decrease pressure and decrease the amount of fat that enters the bloodstream. Patients will be randomly assigned to either the standard preparation (standard reaming), or the reduced pressure preparation (reduced pressure reaming). After surgery, both treatment groups will followed according to standard practices at 2 weeks, 6 weeks, 3 months, and 6 months.

Institution
MUSC
Recruitment Contact
Robert McClam
843-792-7238
mcclamr@musc.edu

Is overprescribing opioids a problem in 3rd molar extraction cases? Save

Date Added
December 27th, 2017
PRO Number
Pro00070753
Researcher
Kevin Schwartzman
Keywords
Pain, Surgery
Summary

This study will be conducted in order to address the possible issue of opioid overprescription in extractions of third molars. Oral surgeons will be surveyed to determine their prescribing patterns. Patients will be surveyed 7 days after the procedure to evaluate their experience with the medication.

Institution
MUSC
Recruitment Contact
Kevin Schwartzman
3018029805
schwarke@musc.edu

Comparison of 0.1 and 0.05mg intrathecal morphine when administered with a multimodal pain regimen for post-cesarean analgesia: a single center, prospective, randomized, single-blinded trial. Save

Date Added
December 19th, 2017
PRO Number
Pro00072393
Researcher
Kathryn Bridges

Silhouette
Keywords
Obstetrics and Gynecology, Pain, Surgery
Summary

This study will compare 0.1mg and 0.05mg of spinal morphine for postoperative pain after scheduled, elective Cesarean delivery. All patients will receive a spinal anesthetic (single injection in the lower back to numb patients from the waist down) for operative anesthesia and will be
randomized into one of two groups: (group 1) 0.1mg spinal morphine and (group 2) 0.05mg spinal morphine. This will be a randomized, single blinded study.

Institution
MUSC
Recruitment Contact
Wanda Jones
843-792-1869
joneswr@musc.edu

Patient and observer graded rhinoplasty scar outcomes: A randomized-controlled trial of fast absorbing versus permanent columellar suture closure. Save

Date Added
December 5th, 2017
PRO Number
Pro00066546
Researcher
Samuel Oyer

Silhouette
Keywords
Surgery
Summary

Traditional sutures used to close the skin after a rhinoplasty are permanent sutures that require removal. These sutures create less inflammation and are thought to produce less visible scars but the process of removing the sutures can be painful and inconvenient for the patient. Some surgeons use fast absorbing sutures that do not require removal, but there have not been strong studies comparing the final scar appearance with these different suture types. This study will evaluate the rhinoplasty scar appearance using traditional permanent sutures compared to fast absorbing sutures.

Institution
MUSC
Recruitment Contact
Samuel Oyer
843-792-0922
oyer@musc.edu

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