This study is for patients that have suffered a femur fracture due to metastatic cancer. The standard of care for this type of fracture is to stabilize the bone with an intramedullary nail. When preparing the femur for the nail, pressure can cause fat to enter the bloodstream and travel to the heart, causing heart and lung complications. The procedure being investigated in this study is called reduced pressure reaming. In this procedure the surgeon will use a device with suction when preparing the bone for the nail in order to decrease pressure and decrease the amount of fat that enters the bloodstream. Patients will be randomly assigned to either the standard preparation (standard reaming), or the reduced pressure preparation (reduced pressure reaming). After surgery, both treatment groups will followed according to standard practices at 2 weeks, 6 weeks, 3 months, and 6 months.
Roughly half of patients who have sarcoma surgery with preoperative radiation have wound complications after surgery. This goal of this study is to look at the levels of oxygen in the skin before and after surgery and compare them to the wound outcome. The information gained could lead to a change in surgical practices.
Low vitamin d levels are common among patients undergoing orthopedic surgery. However, very little is known about how vitamin d affects outcomes in patients undergoing total joint replacement surgery. Our study will look at how common low vitamin d status is among patients undergoing total hip and total knee replacement surgery. We will also look at how vitamin d levels affect complication rates and hospital readmission rates.
Outcomes after anterior spine surgeries are mostly satisfactory, with an extremely low mortality rate. However, there are inherent morbidities, perhaps the most notable of these is injury to the recurrent laryngeal nerve, which can significantly influence patients' quality of life. One method to potentially reduce this is the use of intraoperative monitoring of the recurrent laryngeal nerve during surgery. The central goal of this study is to determine the effectiveness of recurrent laryngeal nerve intraoperative monitoring to reduce the risk of adverse voice outcomes following anterior cervical spine surgeries. Patients will undergo routine ACDF surgery by MUSC spine surgeons, with use of intraoperative neuro-monitoring of the recurrent laryngeal nerve via EMG endotracheal tube. Pre-operative and post-operative swallowing, voice, and overall quality of life standardized questionnaires will be administered, and outcomes evaluated and analyzed.