A MULTICENTER, DOUBLE-BLIND, PLACEBO-CONTROLLED, RANDOMIZED, PARALLEL-GROUP, PHASE 2B STUDY IN TREATMENT-SEEKING PATIENTS WITH CANNABIS USE DISORDER TO ASSESS THE EFFICACY, SAFETY, AND TOLERABILITY OF AEF0117 IN REDUCING CANNABIS USE

Date Added
June 16th, 2022
PRO Number
Pro00119686
Researcher
Kevin Gray

List of Studies


Keywords
Drug Studies, Substance Use
Summary

The purpose of this research is to investigate how a trial drug, AEF0117, influences the effects of cannabis and if it is helpful in the treatment of Cannabis Use Disorder (CUD). This is a 20-week, randomized, double-blind, placebo-controlled, parallel-group outpatient clinical trial that will be conducted at approximately 10 research sites in the US.

Institution
MUSC
Recruitment Contact
Amanda Wagner
843-792-0484
wagne@musc.edu

A Proof-of-Concept Trial of N-Acetylcysteine for Adolescent Alcohol Use Disorder

Date Added
September 4th, 2018
PRO Number
Pro00080921
Researcher
Kevin Gray

List of Studies


Keywords
Adolescents, Alcohol, Substance Use
Summary

The purpose of this study is to evaluate the efficacy of the medication N-acetylcysteine (NAC) to help young people with alcohol use disorder. NAC is an over-the-counter supplement and antioxidant that has been approved by the Food and Drug Administration (FDA) in adults and children for other uses, but has not been approved by the FDA for treatment of alcohol use disorder. All participants will receive brief alcohol counseling during the 8 weeks of medication treatment. Volunteers ages 13-25 are needed for this study.

Institution
MUSC
Recruitment Contact
Youth Collaborative Intake
843-792-9257
youth@musc.edu

N-Acetylcysteine for Youth Cannabis Use Disorder

Date Added
May 3rd, 2016
PRO Number
Pro00054499
Researcher
Kevin Gray

List of Studies


Keywords
Adolescents, Substance Use
Summary

The purpose of this study is to evaluate the efficacy of the medication N-acetylcysteine (NAC) to help young people quit using marijuana. NAC is an over-the-counter supplement and antioxidant that has been approved by the Food and Drug Administration (FDA) in adults and children for other uses, but has not been approved by the FDA for treatment of marijuana use disorder. Volunteers ages 13-21 are needed for this study.

Institution
MUSC
Recruitment Contact
Intake Team
843-792-9257
youth@musc.edu



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