The purpose of the research is to evaluate the effectiveness of using two common drugs together to reduce chronic pain specifically in patients with fibromyalgia. These two drugs are minocycline and N-acetylcysteine . Minocycline is an antibiotic, and N-acetylcysteine is a supplement that can reduce cell damage. Minocycline and N-acetylcysteine are not FDA approved for chronic pain but have been proven in animal studies to interact with important cells in the body that play a major role in the development of chronic pain.

Candidates for this study may or may not report disturbances in odor perception as their primary reason for seeking treatment at MUSC. This study is designed to collect long term, observational data from patients who are being treated with routine clinical care in health clinics at MUSC. Data from clinical questionnaires will be de-identified and stored in a database.

The purpose of this study is to create and maintain a registry, which is a database (a searchable collection of information) about children, adolescents and young adults with pediatric onset of rheumatic diseases. This data may help in the evaluation of the safety and benefit of medications that are prescribed to patients who have rheumatic diseases.