Existence of hematopoietic stem cells-derived cells in human periodontal ligament and alveolar bone. Save

Date Added
May 31st, 2016
PRO Number
Pro00054933
Researcher
Meenal Mehrotra

List of Studies


Profiles_link
Keywords
Dental, Periodontal Disease
Summary

Periodontitis is a major cause of irreversible destruction of tissues leading to a loss of attachment between teeth and their supporting tissues. Several strategies are being tested experimentally to enhance periodontal regeneration, one of them being the use of stem cells.
In this study, eligible participants that are patients of the James B. Edwards College of Dental Medicine scheduled to have their teeth extracted. The teeth being extracted from patients during oral surgery, which otherwise would be discarded, will be donated for laboratory tests.

Institution
MUSC
Recruitment Contact
Meenal Mehrotra
843-792-9289
mehrotra@musc.edu

Charleston ARC Clinical Project 4- Cortical rTMS as a tool to change craving and brain reactivity to alcohol cues Save

Date Added
December 1st, 2015
PRO Number
Pro00050256
Researcher
James Prisciandaro

List of Studies


Profiles_link
Keywords
Alcohol, Brain, Substance Use
Summary

This study examines the effects of non-invasive brain stimulation as a tool to change the brain's response to alcohol cues. There are 3 study visits. At each study visit participants will receive a single session of real or sham transcranial magnetic stimulation (TMS) followed by an MRI scan. This study does not involve alcohol treatment. Interested individuals must be referred for participation by the Charleston Alcohol Research Center Clinical Intake and Assessment Core. For more information, call 792-1222 or email alcoholstudy@musc.edu.

Institution
MUSC
Recruitment Contact
Charleston Alcohol Research Center
(843) 792-1222
alcoholstudy@musc.edu

Phase III Trial of Dose Escalated Radiation Therapy and Standard Androgen Deprivation Therapy (ADT) with a GnRH Agonist vs. Dose Escalated Radiation Therapy and Enhanced ADT with a GnRH Agonist and TAK-700 for Men with High Risk Prostate Cancer Save

Date Added
October 2nd, 2012
PRO Number
Pro00018969
Researcher
David Marshall

List of Studies


Profiles_link
Keywords
Cancer, Prostate
Summary

The purpose of this study is to compare the effects of hormone therapy (androgen deprivation) and TAK-700 plus radiation therapy with hormone therapy (androgen deprivation) and radiation therapy on patients with prostate cancer.
There are 2 treatment groups in this study. Group 1will receive hormone therapy plus radiation therapy only and Group 2 will receive hormone therapy and TAK-700 plus radiation therapy.
Subjects will receive hormone therapy for 24 months. Radiation will be given in 44 treatments over approximately 2 months. If the subject is in Group 2 they will take TAK-700 for 24 months. After the subject is finished receiving therapy, the study doctor will ask the subject to visit the office for follow-up exams every 6 months for 3 years and then once a year.

Institution
MUSC
Recruitment Contact
James Brisendine
843-792-9007
brisend@musc.edu

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