Use of surgical tissue to characterize immune responses in cancer and inflammatory diseases using multi-omic approaches and patient-derived organoids

Date Added
August 28th, 2025
PRO Number
Pro00145021
Researcher
Silvia Guglietta

List of Studies


Keywords
Cancer/Gastrointestinal
Summary

This research study aims to better understand how the immune system functions in human diseases such as cancer and chronic inflammation. We will collect small amounts of tissue that are already being removed during routine surgeries, such as liver transplants or colorectal cancer resections. These tissues would otherwise be discarded. By studying immune cells and molecules within these samples, our team hopes to uncover how inflammation and immune signaling contribute to disease progression. The ultimate goal is to identify new ways to diagnose, monitor, or treat these conditions in the future. Participation does not involve any extra procedures or risk beyond the surgery already being performed.

Institution
MUSC
Recruitment Contact
Silvia Guglietta
(843) 792-9702
gugliett@musc.edu



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