The purpose of this study is to see if an investigational medication is safe and effective in the treatment of IgA nephropathy.

If you are eligible for the study and decide to participate, you will come to MUSC for study visits for about 3 years. These visits will involve blood and urine samples, questions about your health, EKGs and physical exams. You will be randomly assigned to receive the IV study medication or placebo weekly for 12 weeks. Depending on your response to initial treatment, there is a possibility of additional treatment. If you receive placebo in the initial treatment, you may be eligible to receive study medication later in the study.

There is no guarantee that being in this study will help you. There is no cost to participate and compensation is available for the study visits.