Glycemic Profile in At Risk Women Without Diabetes and Macrosomic Fetuses

Date Added
July 19th, 2022
PRO Number
Pro00121993
Researcher
Lauren Yacobucci

List of Studies

Keywords
Obstetrics and Gynecology
Summary

This study is to collect data to assess the benefit of 3rd trimester glucose surveillance in non-diabetic women with big babies.

Institution
MUSC
Recruitment Contact
Jesslyn Payne
843-792-7525
paynej@musc.edu

Frontier Study: A Multicentered Retrospective Chart Review of Non-Invasive Prenatal Testing for Inherited Monogenic Disorders, Rh Incompatibility and Common Aneuploidies

Date Added
January 21st, 2025
PRO Number
Pro00140738
Researcher
Eliza McElwee

List of Studies


Keywords
Obstetrics and Gynecology
Summary

This is a retrospective chart review study looking at the assessment of the clinical performance of single gene non-invasive prenatal screening and comparison to standard of care.

Institution
MUSC
Recruitment Contact
Jesslyn Payne
843-792-7525
paynej@,usc.edu

Infant feeding intentions and risk for breastfeeding attrition among women living with HIV

Date Added
July 3rd, 2025
PRO Number
Pro00142019
Researcher
Britton Gibson

List of Studies

Keywords
Obstetrics and Gynecology
Summary

This is a research study among women living with HIV about their choices in how they feed their infants and the different factors that contribute to those decisions, as well as how those decisions change after giving birth and as their baby grows. This study includes surveys at 2 different time points- once while still pregnant, once approximately 4-6 weeks postpartum. We hope to gain understanding on womens choices about breastfeeding while living with HIV.

Institution
MUSC
Recruitment Contact
Jesslyn Payne
843-792-7525
paynej@musc.edu

The APPROVE Trial: A randomized controlled trial evaluating the efficacy and safety of a prescription digital therapeutic for treatment of overactive bladder in women

Date Added
July 25th, 2025
PRO Number
Pro00144788
Researcher
Amy Askew

List of Studies

Keywords
Obstetrics and Gynecology
Summary

This trial will be a randomized controlled trial designed to determine if women with overactive bladder (OAB), treated with the prescription digital therapeutic (PDTx) demonstrate greater improvement in OAB-related health as compared to standard behavioral education with informational handouts.

Institution
MUSC
Recruitment Contact
Jesslyn Payne
843-792-7525
paynej@musc.edu

Utilizing sFLT-1/PLGF Ratios to Differentiate and Predict Deterioration in Growth-Restricted Fetuses

Date Added
August 15th, 2025
PRO Number
Pro00144214
Researcher
Amartha Gore

List of Studies

Keywords
Obstetrics and Gynecology
Summary

This a blood draw study. Blood samples will be collected every 4 weeks on women diagnosed with fetal growth restriction. We hope it will help to determine other ways to evaluate patients with fetal growth restriction and thus improve outcomes.

Institution
MUSC
Recruitment Contact
Jesslyn Payne
843-792-7525
paynej@musc.edu

A randomized controlled trial of transcutaneous electrical nerve stimulation for pain mitigation during intrauterine device placement

Date Added
September 16th, 2025
PRO Number
Pro00143776
Researcher
Michelle Meglin

List of Studies


Keywords
Obstetrics and Gynecology
Summary

We are conducting this study to determine whether using a TENS (nerve stimulation) unit is effective at reducing pain in women having an IUD inserted.

Institution
MUSC
Recruitment Contact
Jesslyn Payne
843-792-7525
paynej@musc.edu

Progesterone Supplementation for the Prevention of Preeclampsia: A Randomized Controlled Trial

Date Added
June 16th, 2026
PRO Number
Pro00145923
Researcher
Brittany Austin

List of Studies

Keywords
Obstetrics and Gynecology
Summary

Preeclampsia is a pregnancy complication characterized by high blood pressure and signs of organ dysfunction, usually occurring after 20 weeks of pregnancy. It can lead to serious health problems for both the pregnant person and the baby. Although some risk factors for preeclampsia are known, effective strategies to prevent the condition remain limited.

The purpose of this research study is to determine whether vaginal progesterone can help prevent preeclampsia in pregnant individuals. Progesterone is a hormone that is naturally produced during pregnancy and is already used for certain pregnancy-related conditions.

Participants who choose to join the study will be randomly assigned (by chance, like flipping a coin) to receive either vaginal progesterone or no medication. Participants will use the study medication as directed during pregnancy and will continue to receive their routine prenatal care.

Researchers will collect information from prenatal visits, medical records, and delivery outcomes to determine whether progesterone reduces the risk of developing preeclampsia and improves pregnancy outcomes. The information gained from this study may help identify a safe and effective way to prevent preeclampsia and improve the health of pregnant individuals and their babies in future pregnancies.

Institution
MUSC
Recruitment Contact
Jesslyn Payne
843-792-7525
paynej@musc.edu



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