Virtual Monoenergetic and Polyenergetic Reconstructions for Head and Neck CT Angiography: Initial Experience with Photon-Counting CT

Date Added
February 14th, 2023
PRO Number
Pro00123327
Researcher
Maria Spampinato

List of Studies


Keywords
Brain
Summary

The goal of this study is to demonstrate that Photon Counting CT (PC-CT) creates similar or better-quality pictures of the body compared to CT systems we currently use in the clinic. The department of Radiology will be conducting this study using the new PC-CT system at MUSC for imaging of the head, neck, and blood vessels. Participants in this study will receive their normally ordered imaging scan as well as an additional imaging scan on the PC-CT machine. This second scan will take place within a month following the first normally ordered imaging study. This additional scan will be the only extra visit for this research study. Risks are the same as a typical CT scan which can include radiation dose, IV dye allergies, risks from IV, and potential loss of confidentiality.

Institution
MUSC
Recruitment Contact
Samuel Bidwell
843-792-2305
bidwells@musc.edu

PULMONARY EMBOLISM – THROMBUS REMOVAL WITH CATHETER-DIRECTED THERAPY: THE PE-TRACT TRIAL

Date Added
May 10th, 2023
PRO Number
Pro00127854
Researcher
Kevin Dickey

List of Studies

Keywords
Lung, Pulmonary
Summary

This is a study to determine effectiveness of using catheter directed therapy along with medical directed therapy when treating pulmonary embolism versus using medical directed therapy alone.

Institution
MUSC
Recruitment Contact
Samuel Bidwell
843-792-2305
bidwells@musc.edu

A multicenter, prospective, open-label study to evaluate the pharmacokinetics and safety of gadoquatrane in pediatric participants (from birth to <18 years) undergoing contrast-enhanced magnetic resonance imaging (CE-MRI)

Date Added
October 26th, 2023
PRO Number
Pro00128377
Researcher
Justin Chetta

List of Studies

Keywords
Children's Health, Infant
Summary

This is a Phase I (determine the safety of a drug) study that is looking at how long the contrast agent gadoquatrane stays in the plasma (part of blood not including red cells) after a single injection during an MRI in children aged 0-18 years. Gadoquatrane is an investigational drug, which means that it is not approved by the FDA. This study will be assessing the safety of gadoquatrane for up to 8 days following the administration of gadoquatrane at the MRI. Blood samples will be collected three times within the 8 hours following the MRI for analysis of how much gadoquatrane is left in the blood.

Institution
MUSC
Recruitment Contact
Samuel Bidwell
843-792-2305
bidwells@musc.edu

Correlation of photon Counting CT (PCCT) parameters with biomarkers in non-small cell lung cancer (NSCLC) surgical and biopsy specimens.

Date Added
March 5th, 2024
PRO Number
Pro00130202
Researcher
Dhiraj Baruah

List of Studies

Keywords
Cancer/Lung
Summary

The goal of this study is to help compare scans from the new photon counting CT scanner of a solid lung tumor with traditional lab and biopsy results. Subjects enrolled in this study will receive their normal CT scan on the new photon counting CT scanner that has the capacity to provide pictures that are better quality. These images will provide useful information that may lead to future improvements for patients with similar conditions.

Institution
MUSC
Recruitment Contact
Samuel Bidwell
843-792-2305
bidwells@musc.edu



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