Percutaneous coronary intervention (PCI) of chronic total occlusions (CTOs) is increasingly being performed in patients with advanced coronary artery disease, but there is limited information on the techniques utilized and the procedural outcomes. The study is a purely observational study that will not affect the clinical care of the participating subjects. All patients undergoing CTO PCI at MUSC will be identified and data will be collected on patient characteristics, procedural techniques and clinical outcomes. If the patient returns for follow-up clinical care at MUSC this data will be collected after the visit as well. Anonymized data from each center will be sent to Minneapolis Heart Institute Foundation where they will be combined into a single database and analyzed.