Using Connectomics to Characterize Risk for Alzheimer's Disease

Date Added
October 17th, 2017
PRO Number
Pro00071249
Researcher
Jane Joseph

List of Studies


Keywords
Alzheimers, Dementia
Summary

This study will use neuroimaging to understand how the connections in the brain change in Alzheimer's Disease. Changes will also be examined in individuals with mild cognitive impairment and healthy aging. The goal is to discover which brain changes are present in healthy aging and MCI so that future studies can assess the risk for developing Alzheimer's Disease. The study involves blood draw, cognitive testing, MRI, PET scanning, and a 1-year follow-up visit to repeat cognitive testing and MRI scanning.

Institution
MUSC
Recruitment Contact
Katherine Barlis
8437927709
barlis@musc.edu

Connectome Biomarkers for Predicting Alzheimer's Risk in Traumatic Brain Injury

Date Added
July 17th, 2018
PRO Number
Pro00077915
Researcher
Jane Joseph

List of Studies


Keywords
Aging, Alzheimers, Brain, Dementia, Healthy Volunteer Studies, Memory Loss, Military
Summary

Traumatic Brain Injury is a risk factor for Alzheimer's Disease and other dementias. This study will use neuroimaging in Veterans and civilians with a history of TBI or without TBI to understand whether some of the brain changes that occur in Alzheimer's Disease are present in people with a history of TBI. The study is recruiting male and female military Veterans or civilians with or without TBI between the ages of 30 and 65.

Institution
MUSC
Recruitment Contact
Katherine Barlis
843-792-7709
barlis@musc.edu

Simulation Education for Ebola Healthcare Team Competency Phase II

Date Added
January 29th, 2020
PRO Number
Pro00095825
Researcher
Lacey MenkinSmith

List of Studies


Keywords
Education
Summary

The spread of emerging infectious diseases represents a threat to mankind from either nature or bioterrorism. Given the enormous threats, there are many strategies to prevent and treat the next pandemic. Fundamental to all is containment, and this requires protection of HCWs first exposed to and who treat the patients. SimTunes, LLC was launched by MUSC to develop and sell healthcare worker (HCW) simulation educational materials. This study will investigate an educational product created by SimTunes, called Medical Unit Specialized Simulation Training, that will keep healthcare workers prepared for and safe in the next lethal pandemic. The research will test MUSST's superiority over conventional educational methods and its ability to be used in community hospitals and with a new disease.

Institution
MUSC
Recruitment Contact
Joseph Reves
8437925817
revesj@musc.edu

Alcohol Use Disorder as a risk for Alzheimer's Disease: Insights from functional connectome analysis

Date Added
February 18th, 2020
PRO Number
Pro00096201
Researcher
Jane Joseph

List of Studies


Keywords
Alcohol, Alzheimers, Dementia, Non-interventional, Substance Use
Summary

Alcohol Use Disorder (AUD) is a risk factor for Alzheimer's Disease (AD), but more research is needed to identify the potential mechanisms underlying this risk. The present study will use fMRI to examine brain network profiles in mid-life AUD. The goal is to develop techniques to assess risk for Alzheimer's Disease and related dementias. Participation includes cognitive testing and MRI scanning.

Institution
MUSC
Recruitment Contact
Katherine Barlis
843-792-7709
barlis@musc.edu



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