Telerehabilitation for Aphasia

Date Added
March 1st, 2021
PRO Number
Pro00105880
Researcher
Leonardo Bonilha

List of Studies


Keywords
Speech Disorders, Stroke, Stroke Recovery
Summary

To assess comparable efficacy of aphasia therapy administered via telerehab (aphasia remote therapy; ART) to aphasia therapy administered in clinic (in-clinic therapy; I-CT).

Institution
MUSC
Recruitment Contact
Skyler Fontenot
843-792-4088
fontenos@musc.edu

Escitalopram & Language Intervention for Subacute Aphasia

Date Added
February 8th, 2021
PRO Number
Pro00105179
Researcher
Leonardo Bonilha

List of Studies


Keywords
Language, Stroke, Stroke Recovery
Summary

This research is being done to help us understand whether and how the use of a drug, called escitalopram (a selective serotonin reuptake inhibitor or SSRI), may improve language therapy effectiveness, as measured when naming untrained pictures and describing pictures, in individuals with aphasia within three months after a stroke.

Another goal of part of this study is to investigate the particular concentration of certain molecules in the brain of people with following a stroke and how the SSRI might change this. This will allow us to better understand how brains change in people receiving language therapy.

Institution
MUSC
Recruitment Contact
Skyler Fontenot
843-792-0189
fontenos@musc.edu

Localizing Epileptic Networks using 3T MRI

Date Added
September 29th, 2020
PRO Number
Pro00102615
Researcher
Leonardo Bonilha

List of Studies


Keywords
Epilepsy
Summary

The purpose of this research study is to study the capabilities of new methods for studying the brain using Magnetic Resonance Imaging (MRI). MRI already provides detailed images of brain anatomy, but newer methods including new MRI techniques and magnetic resonance spectroscopy expand this capability. These new MRI methods will not require any invasive procedures. If successful, these new methods will expand the information, which can be obtained from MRI studies of the brain in patients with epilepsy.

Institution
MUSC
Recruitment Contact
Lindsey Weissman
843-792-2330
weissmal@musc.edu

Speech entrainment for Aphasia Recovery

Date Added
January 6th, 2020
PRO Number
Pro00091924
Researcher
Leonardo Bonilha

List of Studies


Keywords
Language, Speech Disorders, Stroke, Stroke Recovery
Summary

After a stroke, many people experience a language impairment called aphasia. One of the most debilitating types of aphasia is non-fluent aphasia. Non-fluent aphasia is defined by significantly reduced speech production, with the speaker producing only a few words or even less. Speech entrainment therapy (SET) is a treatment that has been shown to increase fluency in people with non-fluent aphasia. Our study looks to define the best dose of SET that leads to sustained improvements in spontaneous speech production.
Participants who are eligible will undergo baseline language testing, an MRI, and will be randomized into one of 4 treatment groups: SET for 3 weeks, SET for 4.5 weeks, SET for 6 weeks, and no treatment (control group).

Institution
MUSC
Recruitment Contact
Anna Doyle
843-792-3678
doylean@musc.edu



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