Neurocircuit Strategy to Decrease Cocaine Cue Reactivity

Date Added
September 17th, 2019
PRO Number
Pro00091981
Researcher
Hesheng Liu

List of Studies

Keywords
Drug Studies
Summary

The overarching goal of this project is to examine the effect of combining theta burst
stimulation (TBS) and N-acetylcysteine (NAC) on cocaine craving and brain response to cocaine images. Participants (N=96) will undergo a baseline MRI visit to assess craving and brain function, then be randomized to one of four SHAM / Placebo-controlled TBS / NAC treatment conditions. Following 3-days of medication (NAC or Placebo), return to the lab for a second MRI visit where brain function will be assess immediately before and after TBS or SHAM stimulation. Participants will be contacted via phone over the following 3-weeks to assess mood and craving.

Institution
MUSC
Recruitment Contact
Catherine Hubbard
843-792-2528
hubbacat@musc.edu



-- OR --