An International, Multicentre, Prospective, Single-Arm Study to Assess the Effect on Voluntary Movements of AbobotulinumtoxinA 1500 U Administered in Both Upper and Lower Limbs in Conjunction with a Guided Self-Rehabilitation Contract in Adult Subjects with Spastic Hemiparesis Save

Date Added
January 24th, 2017
PRO Number
Pro00062911
Researcher
Wuwei Feng

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Keywords
Drug Studies, Rehabilitation Studies, Stroke, Stroke Recovery
Summary

The purpose of this clinical study is to see whether injections of AbobotulinumtoxinA in the upper limb (arm) and lower limb (leg) in combination with a personal exercise plan can improve voluntary movements in subjects with hemiparesis.

Institution
MUSC
Recruitment Contact
Fay Davis
843-792-0883
davisfa@musc.edu

Determining Transcranial Direct Current Stimulation generated Intracerebral Electric Fields Save

Date Added
February 16th, 2016
PRO Number
Pro00052146
Researcher
Wuwei Feng

Silhouette
Keywords
Brain, Parkinsons
Summary

In this study, we plan to record electric fields (EF) in the brain while transcranial direct current stimulation (tDCS) is applied through the scalp. We will include patients who are scheduled to undergo deep brain stimulation (DBS) procedure to participate in the study, after explaining the procedures, answering any questions and receiving informed consent. The study might prolong the duration of the DBS procedure by a few minutes because of the time taken to apply tDCS. However, no other deviations from standard DBS procedures will be made. That is, no additional DBS electrode penetrations will be performed for research purposes - we will record from DBS electrodes that are being inserted exclusively as a part of clinical care.

Institution
MUSC
Recruitment Contact
Fay Davis
8437920883
davisfa@musc.edu

Prediction and Imaging Biomarker for Post-Stroke Motor Recovery. Save

Date Added
February 18th, 2014
PRO Number
Pro00032062
Researcher
Wuwei Feng

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Keywords
Rehabilitation Studies, Stroke
Summary

During the acute stroke phase, physicians are frequently asked by patients and or their family members about their recovery potential and functional outcome at 3 months. It is of critical importance for clinicians to predict motor outcome from the acute phase. Being able to make outcome predictions in the acute phase allows clinicians to triage patients for the most appropriate rehabilitation and provides the patient and the patient's caregivers with a reasonable expectation of functional recovery. This study aim to predict motor outcomes at 3 months post-stroke using mutliple measures including neuroimaging, genetic and behavioral measures collected during the acute phase.

Institution
MUSC
Recruitment Contact
Fay Davis
843-792-0883
davisfa@musc.edu

Optimizing current and electrode montages for transcranial direct current stimulation in stroke patients. Save

Date Added
January 15th, 2013
PRO Number
Pro00022248
Researcher
Wuwei Feng

Silhouette
Keywords
Rehabilitation Studies, Stroke
Summary

Transcranial direct current brain stimulation is a non-invasive way that has shown motor recovery for stroke patients. This study will investigate the best current and electrode placement for tDCS in stroke patients.

Institution
MUSC
Recruitment Contact
Fay Davis
843-792-0883
davisfa@musc.edu

Modulating the Brain with Bihemispheric Direct Current Stimulation and Constraint-Induced Movement Therapy to Enhance Post-Stroke Motor Recovery Save

Date Added
November 15th, 2011
PRO Number
Pro00012125
Researcher
Wuwei Feng

Silhouette
Keywords
Brain, Rehabilitation Studies, Stroke
Summary

The purpose of this study is to help us to determine whether transcranial direct current stimulation and Constraint-Induced Movement Therapy will enhance motor recovery after stroke.

Institution
MUSC
Recruitment Contact
Fay Davis
843-792-3020
davisfa@musc.edu

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