A PHASE II STUDY OF TAZEMETOSTAT (EPZ-6438) (IND # 138671) IN RECURRENT OR PERSISTENT ENDOMETRIOID OR CLEAR CELL CARCINOMA OF THE OVARY, AND RECURRENT OR PERSISTENT ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA Save

Date Added
August 8th, 2019
PRO Number
Pro00090283
Researcher
Whitney Graybill

List of Studies

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Keywords
Cancer/Gynecological
Summary

This study is for women with ovarian or endometrial cancer. The purpose of the study is to see if the chance of ovarian or endometrial cancer growing can be lowered.

Institution
MUSC
Recruitment Contact
HCC Clinical Trials Office
843-792-9321
hcc-clinical-trials@musc.edu

A Phase 3 Randomized, Double-Blind, Placebo-Controlled Trial of Pembrolizumab (MK-3475) Plus Chemotherapy Versus Chemotherapy Plus Placebo for the First-Line Treatment of Persistent, Recurrent, or Metastatic Cervical Cancer (KEYNOTE-826) Save

Date Added
May 20th, 2019
PRO Number
Pro00082686
Researcher
Whitney Graybill

List of Studies

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Keywords
Cancer, Cancer/Gynecological, Women's Health
Summary

This clinical trial hopes to test the safety and effectiveness of the study drug, pembrolizumab (MK-3475), in combination with chemotherapy, and if this combination will improve survival in women with persistent, recurrent, or metastatic cervical cancer. You may be able to join this study if you are a female at least 18 years of age with persistent, recurrent, or metastatic cervical cancer and have not been treated with systemic chemotherapy, other than chemotherapy that was received with radiation. Participation will be based on specific criteria.
The study duration is estimated at about 2 years, and in some cases may be longer.

Institution
MUSC
Recruitment Contact
HCC Clinical Trials Office
843-792-9321
hcc-clinical-trials@musc.edu

A RANDOMIZED, PHASE II/III STUDY OF PEGYLATED LIPOSOMAL DOXORUBICIN AND CTEP-SUPPLIED ATEZOLIZUMAB (IND #134427) VERSUS PEGYLATED LIPOSOMAL DOXORUBICIN/BEVACIZUMAB AND CTEP-SUPPLIED ATEZOLIZUMAB VERSUS PEGYLATED LIPOSOMAL DOXORUBICIN/BEVACIZUMAB IN PLATINUM RESISTANT OVARIAN CANCER Save

Date Added
April 18th, 2019
PRO Number
Pro00087745
Researcher
Whitney Graybill

List of Studies

Silhouette
Keywords
Cancer/Gynecological
Summary

This study is for women who have ovarian cancer, fallopian tube cancer or primary peritoneal cancer which has grown or recurred. The purpose of this study is to compare any good and bad effects of adding Atezolizumab to the usual chemotherapy (liposomal doxorubicin) and to the usual chemotherapy with bevacizumab. Atezolizumab is a PD-L1 inhibitor that may allow the immune system to recognize and destroy tumor cells.

Institution
MUSC
Recruitment Contact
HCC Clinical Trials Office
843-792-9321
hcc-clinical-trials@musc.edu

Prospective Comparative Effectiveness Trial for Malignant Bowel Obstruction Save

Date Added
June 16th, 2015
PRO Number
Pro00044409
Researcher
Whitney Graybill

List of Studies

Silhouette
Keywords
Bowel, Cancer
Summary

This study is for patients who have a malignant bowel obstruction and their doctor is not sure if surgery or non-surgical treatment will be better for the condition.

Institution
MUSC
Recruitment Contact
HCC Clinical Trials Office
843-792-9321
hcc-clinical-trials@musc.edu

A Pilot Study Evaluating Racial Disparity, Environmental Toxin Exposure and Regulation of Anti-Inflammatory Mediators as Risk Factors for Endometrial Carcinogenesis Save

Date Added
May 22nd, 2014
PRO Number
Pro00030149
Researcher
Whitney Graybill

List of Studies

Silhouette
Keywords
Cancer, Environmental Factors
Summary

The purpose of this study is to determine if environmental toxin exposure differs in African American women as compared to White women with endometrial cancer and to evaluate the relationship between demographic variables and toxin level.

Institution
MUSC
Recruitment Contact
Tamara Jenkins
843-792-6992
saundert@musc.edu

A pilot study evaluating vitamin D deficiency and risk of aggressive uterine cancer in African American as compared to White women Save

Date Added
May 19th, 2014
PRO Number
Pro00030938
Researcher
Whitney Graybill

List of Studies

Silhouette
Keywords
Cancer/Gynecological, Women's Health
Summary

The purpose of this study is to evaluate vitamin D levels in African American and White women who present with a new diagnosis of uterine cancer.

Institution
MUSC
Recruitment Contact
Tamara Jenkins
843-792-6992
saundert@musc.edu

A Randomized Phase II/III Study of Paclitaxel/Carboplatin/Metformin (NSC#91485) Versus Paclitaxel/Carboplatin/Placebo as Initial Therapy for Measurable Stage III or IVA, Stage IVB, or Recurrent Endometrial Cancer Save

Date Added
April 30th, 2014
PRO Number
Pro00034096
Researcher
Whitney Graybill

List of Studies

Silhouette
Keywords
Cancer/Gynecological, Women's Health
Summary

This study is for adult women who have advanced or recurrent endometrial (uterine) cancer. The purpose is to find out if the drug combination of paclitaxel, carboplatin and metformin works better than paclitaxel and carboplatin alone in treating uterine cancer.

Institution
MUSC
Recruitment Contact
Sarah Booker
843-792-9190
bookers@musc.edu

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