The Occlusion Perfusion Catheter for Optimal Delivery of Paclitaxel for the Prevention of Endovascular Restenosis ? Above and Below the Knee Save

Date Added
February 13th, 2018
PRO Number
Pro00073943
Researcher
Thomas Todoran

Silhouette
Keywords
Cardiovascular
Summary

Peripheral vascular interventions are minimally invasive options for the treatment of patients with peripheral arterial disease (PAD). Unfortunately, the effects of this procedure are short-term and there remains a high rate (40-70%) of restenosis (re-narrowing of the arteries). The purpose of this research study is to determine if the use of the catheter for the delivery of the study drug called paclitaxel, will prevent re-narrowing of the blockage of an artery to be treated in the leg.

Institution
MUSC
Recruitment Contact
Kavin Panneerselvam
843-792-0464
panneeer@musc.edu

Assessment of Surrogate Sensors for Hypertension (ASSH) Study Save

Date Added
January 23rd, 2018
PRO Number
Pro00073998
Researcher
Thomas Todoran

Silhouette
Keywords
Heart, Hypertension/ High Blood Pressure
Summary

The purpose of this study is to collect measurements related to the body such as blood pressure, the amount of oxygen in the blood, and heart rhythm recordings. Findings from this study may be used to help design new device-based monitoring technologies in the future.

Continuous blood pressure readings will be obtained during standard of care heart catheterization procedures that include the use of an arterial blood pressure line. Continuous readings of oxygen saturation and ECG will also be obtained. Participants will consist of subjects aged ? 18 years who are scheduled to undergo a cath-lab (cath-lab, percutaneous coronary intervention or equivalent) procedure that includes the use of an arterial blood pressure line.

Institution
MUSC
Recruitment Contact
Renee Baxley
843-792-1105
baxleyr@musc.edu

The RADIANCE-HTN Study: A Study of the ReCor Medical PARADISE System in Clinical Hypertension Save

Date Added
January 12th, 2016
PRO Number
Pro00051260
Researcher
Thomas Todoran

Silhouette
Keywords
Cardiovascular, Hypertension/ High Blood Pressure
Summary

This is a clinical study looking at the effectiveness and safety of a new device called The Paradise System to use for renal denervation in patients who have mild to resistant hypertension. The goal of renal denervation is to lower blood pressure by using ultrasound waves to heat and disable the nerves surrounding the blood vessels leading to the kidneys. It is believed these nerves may be too active in patients with high blood pressure. The study is divided into two groups, those on one to two anti hypertensive medications (Solo) and those on three or more(Trio). The Trio group will stop their current medication regime and be given one of two combination medications while monitoring their blood pressure. If they continue to meet inclusion criteria, they will be randomized to undergo a renal denervation procedure using the new system versus no procedure. Their assignment will not be made known to them until their six month follow up visit. All groups will be followed up to 3 years but patients who did not initially have the procedure will have the opportunity to have it at a later date.

Institution
MUSC
Recruitment Contact
Vijay Paladugu
843-876-5783
paladugc@musc.edu

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