The purpose of this study is to evaluate the efficacy of the medication N-acetylcysteine (NAC) to help young people quit using marijuana. NAC is an over-the-counter supplement and antioxidant that has been approved by the Food and Drug Administration (FDA) in adults and children for other uses, but has not been approved by the FDA for treatment of marijuana use disorder. Volunteers ages 14-21 are needed for this study.
This is a research study to determine if a medication (varenicline) helps young cigarette smokers quit. Smokers aged 14-21 who participate in the study receive medication or placebo and help with quitting during 12 weekly sessions. Smokers under 18 must have parental consent. There is no cost to participate and compensation is available to those that qualify.